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List of works by Klara Valko

2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists. 3. Synthesis, pharmacokinetics, and in vivo potency.

scientific article published in July 2006

A cell-based approach for the early assessment of the phospholipidogenic potential in pharmaceutical research and drug development.

scientific article published on June 2003

A comparative study of the reversed-phase HPLC retention behaviour of S-adenosyl-L-methionine and its related metabolites on Hypersil ODS and Supelcosil LC-ABZ stationary phases

scientific article published on 01 April 1993

Analytical and semi-preparative separation of diastereomeric lipid amino acid conjugates

scientific article published on 01 September 1994

Application of drug efficiency index in drug discovery: a strategy towards low therapeutic dose.

scientific article published on 22 July 2011

Application of high-performance liquid chromatography based measurements of lipophilicity to model biological distribution.

scientific article

Binding measurements of indolocarbazole derivatives to immobilised human serum albumin by high-performance liquid chromatography

scientific article published on 01 February 1996

Chromatographic Hydrophobicity Index by Fast-Gradient RP-HPLC:  A High-Throughput Alternative to log P/log D

scientific article published on 01 June 1997

Chromatographic separation and molecular modelling of triazines with respect to their inhibition of the growth of L1210/R71 cells

scientific article published on 01 February 1992

Detection of the principal synthetic route indicative impurity in lamotrigine

scientific article published on 01 November 1999

Direct Measurement of Intracellular Compound Concentration by RapidFire Mass Spectrometry Offers Insights into Cell Permeability.

scientific article published on 3 September 2015

Displacement chromatography of oligomycins

scientific article published on 01 January 1987

Estimating Unbound Volume of Distribution and Tissue Binding by In Vitro HPLC-Based Human Serum Albumin and Immobilised Artificial Membrane-Binding Measurements ⬇️

scientific article published on October 1, 2010

Estimation of Volume of Distribution in Humans from High Throughput HPLC-Based Measurements of Human Serum Albumin Binding and Immobilized Artificial Membrane Partitioning

scientific article published on 01 November 2006

Fast gradient HPLC method to determine compounds binding to human serum albumin. Relationships with octanol/water and immobilized artificial membrane lipophilicity.

scientific article published in November 2003

Fast liquid chromatographic method to determine compounds binding to human serum albumin

scientific article published in January 2003

Improving the passive permeability of macrocyclic peptides: Balancing permeability with other physicochemical properties

scientific article published on 28 November 2014

In vitro measurement of drug efficiency index to aid early lead optimization

scientific article published on 28 August 2012

Interrogating the relationship between rat in vivo tissue distribution and drug property data for >200 structurally unrelated molecules.

scientific article

Lipophilicity and pKa estimates from gradient high-performance liquid chromatography

scientific article published in August 2002

Microwave extraction. A novel sample preparation method for chromatography

scientific article published on 01 December 1986

Modeling cellular pharmacokinetics of 14- and 15-membered macrolides with physicochemical properties.

scientific article published on 5 January 2011

Nitric oxide effects on polyamine pathways in cultured hepatocytes.

scientific article published on August 1994

Physicochemical profile of macrolides and their comparison with small molecules.

scientific article

Rapid method for the estimation of octanol/water partition coefficient (log P(oct)) from gradient RP-HPLC retention and a hydrogen bond acidity term (zetaalpha(2)(H)).

scientific article

Relationships between the chromatographic retention data and the effects of nucleoside derivatives in highly metastatic 3LL cells

scientific article published on July 1, 1992

Supreme activity of gramicidin S against resistant, persistent and biofilm cells of staphylococci and enterococci

scientific article published on 29 November 2019

Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzothiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitors.

scientific article published on 27 May 2009

The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits

scientific article

Two-dimensional high-performance liquid chromatographic method for assaying S-adenosyl-L-methionine and its related metabolites in tissues

scientific article published on 01 September 1993

[Development of methods for the chromatographic analysis of Hevizos]

scientific article published on 01 July 1993

[Gas chromatographic determination of the water-octanol partition constant]

scientific article published on 01 September 1983

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