List of works - Andrew M Riley

2-O-(2-Aminoethyl)-myo-inositol 1,4,5-trisphosphate as a novel ligand for conjugation: physicochemical properties and synthesis of a new Ins(1,4,5)P(3) affinity matrix.

scientific article published in May 2004

A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase

scientific article published on 19 September 2018

A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion

scientific article (publication date: 2016)

A Synthetic Polyphosphoinositide Headgroup Surrogate in Complex with SHIP2 Provides a Rationale for Drug Discovery ⬇️

scientific article published on February 27, 2012

A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop

scientific article published on 25 April 2022

A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate.

scientific article published on 4 June 2018

Cellular internalisation of an inositol phosphate visualised by using fluorescent InsP5

scientific article published on 6 December 2013

Contribution of Phosphates and Adenine to the Potency of Adenophostins at the IP3 Receptor: Synthesis of All Possible Bisphosphates of Adenophostin A ⬇️

scientific article published on February 8, 2012

Designer small molecules to target calcium signalling.

scientific article published on June 2015

Determination of neo- and D-chiro-inositol hexakisphosphate in soils by solution 31P NMR spectroscopy

scientific article published on 20 April 2012

Fibrinogen - a possible extracellular target for inositol phosphates

scientific article published on December 2012

First synthetic analogues of diphosphoinositol polyphosphates: interaction with PP-InsP5 kinase ⬇️

scientific article published on November 28, 2012

Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response

scientific article (publication date: February 2014)

Inframolecular acid-base and coordination properties towards Na(+) and Mg(2+) of myo-inositol 1,3,4,5,6-pentakisphosphate: a structural approach to biologically relevant species.

scientific article

Inositol hexakisphosphate increases the size of platelet aggregates

scientific article published on 14 December 2018

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

scientific article

Regioselective hydrolysis of myo-inositol 1,3,5-orthobenzoate via a 1,2-bridged 2'-phenyl-1',3'-dioxolan-2'-ylium ion provides a rapid route to the anticancer agent Ins(1,3,4,5,6)P5

scientific article published on 07 June 2006

Regioselective opening of myo-inositol orthoesters: mechanism and synthetic utility.

scientific article published on 5 March 2013

Selective determinants of inositol 1,4,5-trisphosphate and adenophostin A interactions with type 1 inositol 1,4,5-trisphosphate receptors.

scientific article published on November 2010

Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by adenophostin A and its analogues

scientific article

Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by analogues of IP3

scientific article

Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85alpha Src homology 2 domains with phosphoinositides and inositol polyphosphates

scientific article

Subtype-selective regulation of IP3 receptors by thimerosal via cysteine residues within the IP3-binding core and suppressor domain ⬇️

scientific article published on April 15, 2013

Synthesis of an α-phosphono-α,α-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP7

scientific article published on 07 June 2019

Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery

scientific article

Synthetic tools for studying the chemical biology of InsP8.

scientific article

The inositol pyrophosphate 5-InsP7 drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α

scientific article published on 28 October 2020

scyllo-inositol pentakisphosphate as an analogue of myo-inositol 1,3,4,5,6-pentakisphosphate: chemical synthesis, physicochemistry and biological applications.

scientific article published in July 2006

List of works by Andrew M Riley

2-O-(2-Aminoethyl)-myo-inositol 1,4,5-trisphosphate as a novel ligand for conjugation: physicochemical properties and synthesis of a new Ins(1,4,5)P(3) affinity matrix.

A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase

A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion

A Synthetic Polyphosphoinositide Headgroup Surrogate in Complex with SHIP2 Provides a Rationale for Drug Discovery ⬇️

A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop

A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate.

Cellular internalisation of an inositol phosphate visualised by using fluorescent InsP5

Contribution of Phosphates and Adenine to the Potency of Adenophostins at the IP3 Receptor: Synthesis of All Possible Bisphosphates of Adenophostin A ⬇️

Designer small molecules to target calcium signalling.

Determination of neo- and D-chiro-inositol hexakisphosphate in soils by solution 31P NMR spectroscopy

Fibrinogen - a possible extracellular target for inositol phosphates

First synthetic analogues of diphosphoinositol polyphosphates: interaction with PP-InsP5 kinase ⬇️

Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response

Inframolecular acid-base and coordination properties towards Na(+) and Mg(2+) of myo-inositol 1,3,4,5,6-pentakisphosphate: a structural approach to biologically relevant species.

Inositol hexakisphosphate increases the size of platelet aggregates

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

Regioselective hydrolysis of myo-inositol 1,3,5-orthobenzoate via a 1,2-bridged 2'-phenyl-1',3'-dioxolan-2'-ylium ion provides a rapid route to the anticancer agent Ins(1,3,4,5,6)P5

Regioselective opening of myo-inositol orthoesters: mechanism and synthetic utility.

Selective determinants of inositol 1,4,5-trisphosphate and adenophostin A interactions with type 1 inositol 1,4,5-trisphosphate receptors.

Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by adenophostin A and its analogues

Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by analogues of IP3

Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85alpha Src homology 2 domains with phosphoinositides and inositol polyphosphates

Subtype-selective regulation of IP3 receptors by thimerosal via cysteine residues within the IP3-binding core and suppressor domain ⬇️

Synthesis of an α-phosphono-α,α-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP7

Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery

Synthetic tools for studying the chemical biology of InsP8.

The inositol pyrophosphate 5-InsP7 drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α

scyllo-inositol pentakisphosphate as an analogue of myo-inositol 1,3,4,5,6-pentakisphosphate: chemical synthesis, physicochemistry and biological applications.