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List of works by Ronald N. Hines

A Chemical Category-Based Prioritization Approach for Selecting 75 Per- and Polyfluoroalkyl Substances (PFAS) for Tiered Toxicity and Toxicokinetic Testing

article

A TLR5 (g.1174C > T) variant that encodes a stop codon (R392X) is associated with bronchopulmonary dysplasia

scientific article published on 04 November 2011

A Time-Embedding Network Models the Ontogeny of 23 Hepatic Drug Metabolizing Enzymes

scientific article published on 29 July 2019

A genetic polymorphism in the regulatory sequences of human CYP2E1: association with increased chlorzoxazone hydroxylation in the presence of obesity and ethanol intake

scientific article published on 01 September 1998

A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities

scientific article

Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny.

scientific article published on 29 January 2016

Altered regulation of the cytochrome P4501A1 gene: novel inducer-independent gene expression in pulmonary carcinoma cell lines

scientific article published on 01 December 1989

Application of epigenetic data in human health risk assessment

scientific article published on 01 November 2017

Approaches for assessing risks to sensitive populations: lessons learned from evaluating risks in the pediatric population

scientific article

Baseline Chromatin Modification Levels May Predict Interindividual Variability in Ozone-Induced Gene Expression

scientific article published on 29 December 2015

Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria.

scientific article

Demonstration of microsomal oxygenation of the benzo ring of 6-nitrobenzo[a]pyrene by thin-layer chromatography

scientific article published on 01 May 1984

Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages

scientific article published on 22 February 2017

Developmental Expression of the Cytosolic Sulfotransferases in Human Liver.

scientific article

Developmental expression of drug metabolizing enzymes: impact on disposition in neonates and young children.

scientific article published on 03 July 2012

Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver

scientific article published on 20 April 2016

Flavin-containing monooxygenase genetic polymorphism: impact on chemical metabolism and drug development.

scientific article

Functional characterization of the human CYP1A1 negative regulatory element: modulation of Ah receptor mediated transcriptional activity ⬇️

scientific article published on May 1, 1998

Further Characterization of the Major and Minor RabbitFMO1Promoters and Identification of both Positive and Negative Distal Regulatory Elements ⬇️

scientific article published on October 1, 1997

FutureTox III: Bridges for Translation.

scientific article published on 25 October 2016

Gene structure and nucleotide sequence for rat cytochrome P-450c.

scientific article

Glucocorticoid regulation of the rat cytochrome P450c (P450IA1) gene: receptor binding within intron I.

scientific article published on February 1989

Hepatic differentiation of amniotic epithelial cells

scientific article

Hepatobiliary disposition of 17-OHPC and taurocholate in fetal human hepatocytes: a comparison with adult human hepatocytes

scientific article published on 5 November 2012

Human Hepatic CYP2E1 Expression during Development

scientific article published on October 1, 2003

Human hepatic UGT2B15 developmental expression

scientific article

Human hepatic flavin-containing monooxygenases 1 (FMO1) and 3 (FMO3) developmental expression

scientific article (publication date: February 2002)

Identification of multiple regulatory elements on the human cytochrome P450IA1 gene

scientific article published on 01 September 1988

Identification of tissue-specific DNase I hypersensitive sites in the rabbit flavin-containing monooxygenase form 2 gene.

scientific article published on August 1996

Implication of the "4S" polycyclic aromatic hydrocarbon binding protein in the transregulation of rat cytochrome P-450c expression

scientific article published in 1985

Induction of cytochrome P-450IA1 gene expression in human breast tumour cell lines.

scientific article published on January 1988

Induction of cytochrome P450 1A1 gene expression, oxidative stress, and genotoxicity by carbaryl and thiabendazole in transfected human HepG2 and lymphoblastoid cells.

scientific article

Inhibition of metabolism-mediated cytotoxicity by 1,1-disubstituted hydrazines in mouse mastocytoma (line P815) cells

scientific article published on 01 September 1982

Integration of Life-Stage Physiologically Based Pharmacokinetic Models with Adverse Outcome Pathways and Environmental Exposure Models to Screen for Environmental Hazards

scientific article published on 04 May 2016

Large-scale purification of plasmid DNA by anion-exchange high-performance liquid chromatography

scientific article published on 01 March 1992

Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene.

scientific article

Molecular induction by phenobarbital of a rat hepatic form of cytochrome P-450: Expression of a 4-kilobase messenger RNA ⬇️

scientific article published on December 1, 1983

NTP-CERHR Expert Panel Report on the reproductive and developmental toxicity of fluoxetine.

scientific article published in August 2004

Ontogeny of human hepatic cytochromes P450.

scientific article published on January 2007

Ontogeny of plasma proteins, albumin and binding of diazepam, cyclosporine, and deltamethrin

scientific article

Oxidative stress-responsive transcription factor NRF2 is not indispensable for the human hepatic Flavin-containing monooxygenase-3 (FMO3) gene expression in HepG2 cells

scientific article

Partial Characterization of the Human CYP1A1 Negatively Acting Transcription Factor and Mutational Analysis of Its Cognate DNA Recognition Sequence ⬇️

scientific article published on September 1, 1995

Population-based analysis of methadone distribution and metabolism using an age-dependent physiologically based pharmacokinetic model

scientific article published on 07 June 2006

Prediction of Warfarin Dose in Pediatric Patients: An Evaluation of the Predictive Performance of Several Models.

scientific article published on May 2016

Regulation of cytochrome P-450c by glucocorticoids and polycyclic aromatic hydrocarbons in cultured fetal rat hepatocytes

scientific article published on 01 April 1986

Regulation of flavin-containing monooxygenase 1 expression by ying yang 1 and hepatic nuclear factors 1 and 4.

scientific article

Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny

scientific article published on 26 February 2016

Specific nuclear protein binding to a negative regulatory element on the human CYP1A1 gene

scientific article published on 01 August 1993

Structural details of the human cytochrome P-450c gene

scientific article published on 01 July 1987

The Impact of Scaling Factor Variability on Risk-Relevant Pharmacokinetic Outcomes in Children: A Case Study Using Bromodichloromethane (BDCM)

scientific article published on 01 February 2019

The NFKB1 (g.-24519delATTG) variant is associated with necrotizing enterocolitis (NEC) in premature infants.

scientific article

The characterization of an inhibitory complex formed with cytochrome P-450 and a metabolite of 1,1-disubstituted hydrazines

scientific article published on 01 July 1980

The molecular cloning of cytochrome P-450c information

scientific article published on 01 December 1981

The oxidation of hydrazine derivatives catalyzed by the purified liver microsomal FAD-containing monooxygenase

scientific article published on 01 May 1981

Tissue-specific expression of flavin-containing monooxygenase (FMO) forms 1 and 2 in the rabbit

scientific article published on 01 March 1995

Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes.

scientific article

Variation in induction of human placental CYP2E1: possible role in susceptibility to fetal alcohol syndrome?

scientific article published on 01 June 1997

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