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List of works by Ronald N. Hines

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Ontogeny of human hepatic cytochromes P450.

scientific article published on January 2007
A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities

scientific article
Human hepatic flavin-containing monooxygenases 1 (FMO1) and 3 (FMO3) developmental expression

scientific article (publication date: February 2002)
Developmental expression of drug metabolizing enzymes: impact on disposition in neonates and young children.

scientific article published on 03 July 2012
Human Hepatic CYP2E1 Expression during Development

scientific article published on October 1, 2003
Hepatic differentiation of amniotic epithelial cells

scientific article
The NFKB1 (g.-24519delATTG) variant is associated with necrotizing enterocolitis (NEC) in premature infants.

scientific article
Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria.

scientific article
Population-based analysis of methadone distribution and metabolism using an age-dependent physiologically based pharmacokinetic model

scientific article published on 07 June 2006
A genetic polymorphism in the regulatory sequences of human CYP2E1: association with increased chlorzoxazone hydroxylation in the presence of obesity and ethanol intake

scientific article published on 01 September 1998
Identification of multiple regulatory elements on the human cytochrome P450IA1 gene

scientific article published on 01 September 1988
Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene.

scientific article
Partial Characterization of the Human CYP1A1 Negatively Acting Transcription Factor and Mutational Analysis of Its Cognate DNA Recognition Sequence

scientific article published on September 1, 1995
Approaches for assessing risks to sensitive populations: lessons learned from evaluating risks in the pediatric population

scientific article
Glucocorticoid regulation of the rat cytochrome P450c (P450IA1) gene: receptor binding within intron I.

scientific article published on February 1989
A TLR5 (g.1174C > T) variant that encodes a stop codon (R392X) is associated with bronchopulmonary dysplasia

scientific article published on 04 November 2011
Ethnic differences in allelic frequency of two flavin-containing monooxygenase 3 (FMO3) polymorphisms: linkage and effects on in vivo and in vitro FMO activities

scientific article published on January 1, 2002
Flavin-containing monooxygenase genetic polymorphism: impact on chemical metabolism and drug development.

scientific article
Induction of cytochrome P450 1A1 gene expression, oxidative stress, and genotoxicity by carbaryl and thiabendazole in transfected human HepG2 and lymphoblastoid cells.

scientific article
Hepatobiliary disposition of 17-OHPC and taurocholate in fetal human hepatocytes: a comparison with adult human hepatocytes

scientific article published on 5 November 2012
Induction of cytochrome P-450IA1 gene expression in human breast tumour cell lines.

scientific article published on January 1988
NTP-CERHR Expert Panel Report on the reproductive and developmental toxicity of fluoxetine.

scientific article published in August 2004
Human hepatic UGT2B15 developmental expression

scientific article
Functional characterization of the human CYP1A1 negative regulatory element: modulation of Ah receptor mediated transcriptional activity

scientific article published on May 1, 1998
Gene structure and nucleotide sequence for rat cytochrome P-450c.

scientific article
Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes.

scientific article
Integration of Life-Stage Physiologically Based Pharmacokinetic Models with Adverse Outcome Pathways and Environmental Exposure Models to Screen for Environmental Hazards

scientific article published on 04 May 2016
Ontogeny of plasma proteins, albumin and binding of diazepam, cyclosporine, and deltamethrin

scientific article
Tissue-specific expression of flavin-containing monooxygenase (FMO) forms 1 and 2 in the rabbit

scientific article published on 01 March 1995
Variation in induction of human placental CYP2E1: possible role in susceptibility to fetal alcohol syndrome?

scientific article published on 01 June 1997
Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny.

scientific article published on 29 January 2016
Regulation of flavin-containing monooxygenase 1 expression by ying yang 1 and hepatic nuclear factors 1 and 4.

scientific article
Toll-like receptor genetic variants are associated with Gram-negative infections in VLBW infants

scientific article published on July 18, 2013
Baseline Chromatin Modification Levels May Predict Interindividual Variability in Ozone-Induced Gene Expression

scientific article published on 29 December 2015
Altered regulation of the cytochrome P4501A1 gene: novel inducer-independent gene expression in pulmonary carcinoma cell lines

scientific article published on 01 December 1989
Regulation of cytochrome P-450c by glucocorticoids and polycyclic aromatic hydrocarbons in cultured fetal rat hepatocytes

scientific article published on 01 April 1986
Raising the Bar for Reproducible Science at the U.S. Environmental Protection Agency Office of Research and Development

scientific article published on March 19, 2015
Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver

scientific article published on 20 April 2016
Current Research and Opportunities to Address Environmental Asbestos Exposures

scientific article published on August 1, 2015
FutureTox III: Bridges for Translation.

scientific article published on 25 October 2016
Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages

scientific article published on 22 February 2017
Implication of the "4S" polycyclic aromatic hydrocarbon binding protein in the transregulation of rat cytochrome P-450c expression

scientific article published in 1985
Specific nuclear protein binding to a negative regulatory element on the human CYP1A1 gene

scientific article published on 01 August 1993
A Chemical Category-Based Prioritization Approach for Selecting 75 Per- and Polyfluoroalkyl Substances (PFAS) for Tiered Toxicity and Toxicokinetic Testing

article
Large-scale purification of plasmid DNA by anion-exchange high-performance liquid chromatography

scientific article published on 01 March 1992
Further Characterization of the Major and Minor RabbitFMO1Promoters and Identification of both Positive and Negative Distal Regulatory Elements

scientific article published on October 1, 1997
Use of the RISK21 roadmap and matrix: human health risk assessment of the use of a pyrethroid in bed netting

scientific article published on October 30, 2015
Prediction of Warfarin Dose in Pediatric Patients: An Evaluation of the Predictive Performance of Several Models.

scientific article published on May 2016
Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny

scientific article published on 26 February 2016
The oxidation of hydrazine derivatives catalyzed by the purified liver microsomal FAD-containing monooxygenase

scientific article published on 01 May 1981

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