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List of works by Kong-Peng Lam

A Conformational Change in Cytochromecof Apoptotic and Necrotic Cells Is Detected by Monoclonal Antibody Binding and Mimicked by Association of the Native Antigen with Synthetic Phospholipid Vesicles†

scientific article published on 01 March 1999

Aberrant presentation of self-lipids by autoimmune B cells depletes peripheral iNKT cells

scientific article published on 25 September 2014

Activated dectin-1 localizes to lipid raft microdomains for signaling and activation of phagocytosis and cytokine production in dendritic cells.

scientific article published on 12 June 2009

Adaptor protein DOK3 promotes plasma cell differentiation by regulating the expression of programmed cell death 1 ligands

scientific article

Anti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cells

scientific article

B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development.

scientific article

B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity.

scientific article

B-1 cells: unique origins and functions.

scientific article published on February 1996

BAFF costimulation of Toll-like receptor-activatedB-1 cells

scientific article published on 01 July 2006

BCR-dependent lineage plasticity in mature B cells

scientific article published on 01 February 2019

Basal immunoglobulin signaling actively maintains developmental stage in immature B cells

scientific article

Bruton's tyrosine kinase and protein kinase C µ are required for TLR7/9-induced IKKα and IRF-1 activation and interferon-β production in conventional dendritic cells

scientific article

Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response

scientific article published on 19 February 2015

Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response

scientific article published on 27 March 2012

Bruton's tyrosine kinase separately regulates NFkappaB p65RelA activation and cytokine interleukin (IL)-10/IL-12 production in TLR9-stimulated B Cells

scientific article published on 13 February 2008

Combined deficiencies in Bruton tyrosine kinase and phospholipase Cgamma2 arrest B-cell development at a pre-BCR+ stage

scientific article published on 12 December 2006

Comprehensive analysis of CD4+ T cells in the decision between tolerance and immunity in vivo reveals a pivotal role for ICOS.

scientific article published in June 2012

DOK3 is required for IFN-β production by enabling TRAF3/TBK1 complex formation and IRF3 activation.

scientific article published on 13 June 2014

Deficiency in TNFRSF13B (TACI) expands T-follicular helper and germinal center B cells via increased ICOS-ligand expression but impairs plasma cell survival

scientific article published on September 4, 2012

Delayed cellular maturation and decreased immunoglobulin kappa light chain production in immature B lymphocytes lacking B cell linker protein.

scientific article published on July 2002

Dok-3 plays a nonredundant role in negative regulation of B-cell activation

scientific article published on 15 March 2007

Dok3-protein phosphatase 1 interaction attenuates Card9 signaling and neutrophil-dependent antifungal immunity

scientific article published on 10 June 2019

Fas apoptosis inhibitory molecule is upregulated by IGF-1 signaling and modulates Akt activation and IRF4 expression in multiple myeloma.

scientific article

Fas apoptosis inhibitory molecule regulates T cell receptor-mediated apoptosis of thymocytes by modulating Akt activation and Nur77 expression.

scientific article

Functional hierarchy and relative contribution of the CD28/B7 and ICOS/B7-H2 costimulatory pathways to T cell-mediated delayed-type hypersensitivity.

scientific article published on 27 February 2009

Genetic deletion of faim reveals its role in modulating c-FLIP expression during CD95-mediated apoptosis of lymphocytes and hepatocytes.

scientific article published on 20 March 2009

Impaired germinal center formation and recall T-cell–dependent immune responses in mice lacking the costimulatory ligand B7-H2

scientific article published on April 24, 2003

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

scientific article published in September 1997

Leupaxin negatively regulates B cell receptor signaling

scientific article

Macrophage polarization to a unique phenotype driven by B cells.

scientific article

Major histocompatibility complex class II expression distinguishes two distinct B cell developmental pathways during ontogeny.

scientific article

Memory B-cell persistence is independent of persisting immunizing antigen.

scientific article published in October 2000

Mir-17-92 regulates bone marrow homing of plasma cells and production of immunoglobulin G2c

scientific article published on 17 April 2015

Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells

scientific article published on 23 June 2014

Peritoneal CD5+ B-1 cells have signaling properties similar to tolerant B cells

scientific article published on 17 June 2002

Pharmacologic inhibition of MEK-ERK signaling enhances Th17 differentiation.

scientific article

Production of functional soluble Dectin-1 glycoprotein using an IRES-linked destabilized-dihydrofolate reductase expression vector

scientific article

Proteomic analysis of the SH2 domain-containing leukocyte protein of 76 kDa (SLP76) interactome in resting and activated primary mast cells [corrected].

scientific article published on 2 July 2013

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

scientific article published on March 6, 1992

RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection

scientific article

Rapid elimination of mature autoreactive B cells demonstrated by Cre-induced change in B cell antigen receptor specificity in vivo

scientific article published on October 27, 1998

Regulation of mouse inducible costimulator (ICOS) expression by Fyn-NFATc2 and ERK signaling in T cells

scientific article published on 31 July 2006

Shp1 signalling is required to establish the long-lived bone marrow plasma cell pool

scientific article

Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo

scientific article published on 14 February 2005

T helper cell-specific regulation of inducible costimulator expression via distinct mechanisms mediated by T-bet and GATA-3

scientific article published on 06 November 2007

The RNase III enzyme Dicer is essential for germinal center B-cell formation.

scientific article published on 23 November 2011

The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs

scientific article

Transmembrane activator, calcium modulator, and cyclophilin ligand interactor drives plasma cell differentiation in LPS-activated B cells.

scientific article published on 8 May 2009