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List of works by Yiguo Zhang

A Naturally-Occurring Dominant-Negative Inhibitor of Keap1 Competitively against Its Negative Regulation of Nrf2

scientific article published on 24 July 2018

Arsenite-induced phosphorylation of histone H3 at serine 10 is mediated by Akt1, extracellular signal-regulated kinase 2, and p90 ribosomal S6 kinase 2 but not mitogen- and stress-activated protein kinase 1.

scientific article published on 14 January 2003

Ataxia telangiectasia mutated proteins, MAPKs, and RSK2 are involved in the phosphorylation of STAT3.

scientific article

COOH-terminal Src kinase-mediated c-Jun phosphorylation promotes c-Jun degradation and inhibits cell transformation.

scientific article

Distinct isoforms of Nrf1 diversely regulate different subsets of its cognate target genes

article

Evidence of STAT1 phosphorylation modulated by MAPKs, MEK1 and MSK1.

scientific article published on 12 February 2004

Glucose Starvation-Induced Rapid Death of Nrf1α-Deficient, but Not Nrf2-Deficient, Hepatoma Cells Results from Its Fatal Defects in the Redox Metabolism Reprogramming

scientific article published on 28 July 2020

Identification of topological determinants in the N-terminal domain of transcription factor Nrf1 that control its orientation in the endoplasmic reticulum membrane

scientific article published in September 2010

Involvement of ERKs and mitogen- and stress-activated protein kinase in UVC-induced phosphorylation of ATF2 in JB6 cells

scientific article

Involvement of ERKs, RSK2 and PKR in UVA-induced signal transduction toward phosphorylation of eIF2alpha (Ser(51)).

scientific article published on 2 April 2007

Involvement of c-jun NH(2)-terminal kinases in resveratrol-induced activation of p53 and apoptosis

scientific article published on April 2002

Involvement of the acid sphingomyelinase pathway in uva-induced apoptosis

scientific article

MSK1 and JNKs mediate phosphorylation of STAT3 in UVA-irradiated mouse epidermal JB6 cells.

scientific article

Molecular and cellular basis for the unique functioning of Nrf1, an indispensable transcription factor for maintaining cell homoeostasis and organ integrity

scientific article published on April 2016

NF-E2-related factor 2 serves a key function in resistance to malignant transformation of BEAS-2B cells induced by coal tar pitch.

scientific article published in February 2018

NS-398 and piroxicam suppress UVB-induced activator protein 1 activity by mechanisms independent of cyclooxygenase-2.

scientific article published on 13 November 2002

Nach Is a Novel Subgroup at an Early Evolutionary Stage of the CNC-bZIP Subfamily Transcription Factors from the Marine Bacteria to Humans

scholarly article by Yu-Ping Zhu published in September 2018

Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum

scientific article

Novel flavagline-like compounds with potent Fli-1 inhibitory activity suppress diverse types of leukemia

scientific article published on 20 November 2018

Nrf1 Is Endowed with a Dominant Tumor-Repressing Effect onto the Wnt/β-Catenin-Dependent and Wnt/β-Catenin-Independent Signaling Networks in the Human Liver Cancer

scientific article published on 23 March 2020

Nrf1 and Nrf2 transcription factors regulate androgen receptor transactivation in prostate cancer cells

scientific article published on 22 January 2014

Nrf1D Is the First Candidate Secretory Transcription Factor in the Blood Plasma, Its Precursor Existing as a Unique Redox-Sensitive Transmembrane CNC-bZIP Protein in Hemopoietic and Somatic Tissues

scholarly article by Jianxin Yuan published in September 2018

Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity.

scientific article

Nrf2- and Bach1 May Play a Role in the Modulation of Ultraviolet A-Induced Oxidative Stress by Acetyl-11-Keto-β-Boswellic Acid in Skin Keratinocytes.

scientific article published on February 2017

Oncogenic Activation of Nrf2, Though as a Master Antioxidant Transcription Factor, Liberated by Specific Knockout of the Full-Length Nrf1α that Acts as a Dominant Tumor Repressor

Organ-specific distribution of AP-1 in AP-1 luciferase transgenic mice during the maturation process.

scientific article published in February 2001

Phosphorylation of 4E-BP1 is mediated by the p38/MSK1 pathway in response to UVB irradiation

scientific article (publication date: 15 March 2002)

Pifithrin-alpha promotes p53-mediated apoptosis in JB6 cells

scientific article published in July 2003

Requirement of ATM in UVA-induced signaling and apoptosis.

scientific article

Signal transduction pathways involved in phosphorylation and activation of p70S6K following exposure to UVA irradiation.

scientific article published on 28 March 2001

Synergism and Antagonism of Two Distinct, but Confused, Nrf1 Factors in Integral Regulation of the Nuclear-to-Mitochondrial Respiratory and Antioxidant Transcription Networks

scientific article published on 16 November 2020

TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells

scientific article

The C-terminal domain of Nrf1 negatively regulates the full-length CNC-bZIP factor and its shorter isoform LCR-F1/Nrf1β; both are also inhibited by the small dominant-negative Nrf1γ/δ isoforms that down-regulate ARE-battery gene expression

scientific article

The NHB1 (N-terminal homology box 1) sequence in transcription factor Nrf1 is required to anchor it to the endoplasmic reticulum and also to enable its asparagine-glycosylation.

scientific article published on December 2007

The Nrf1 CNC/bZIP protein is a nuclear envelope-bound transcription factor that is activated by t-butyl hydroquinone but not by endoplasmic reticulum stressors

scientific article

The Nrf3 transcription factor is a membrane-bound glycoprotein targeted to the endoplasmic reticulum through its N-terminal homology box 1 sequence

scientific article

The membrane-topogenic vectorial behaviour of Nrf1 controls its post-translational modification and transactivation activity

scientific article published on January 2013

The p53 protein is a novel substrate of ribosomal S6 kinase 2 and a critical intermediary for ribosomal S6 kinase 2 and histone H3 interaction.

scientific article

The selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expression

scientific article

The signal transduction networks required for phosphorylation of STAT1 at Ser727 in mouse epidermal JB6 cells in the UVB response and inhibitory mechanisms of tea polyphenols.

scientific article

Transcription factor Nrf1 is negatively regulated by its O-GlcNAcylation status

scientific journal article

Transcription factor Nrf1 is topologically repartitioned across membranes to enable target gene transactivation through its acidic glucose-responsive domains

scientific article

Unification of Opposites between Two Antioxidant Transcription Factors Nrf1 and Nrf2 in Mediating Distinct Cellular Responses to the Endoplasmic Reticulum Stressor Tunicamycin

scientific article published on 19 December 2019

eIF2 alpha phosphorylation alleviates UVA-induced HO-1 expression in mouse epidermal cells

scientific article published on 01 December 2018

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