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List of works by Bruno De Geest

"Giant" hollow multilayer capsules by microfluidic templating

scientific article

A Generic Polymer-Protein Ligation Strategy for Vaccine Delivery

scientific article published on 26 January 2016

A Synthetic, Transiently Thermoresponsive Homopolymer with UCST Behaviour within a Physiologically Relevant Window

scientific article published on 30 April 2019

A single step process for the synthesis of antigen laden thermosensitive microparticles

article by Bruno De Geest et al published 2010 in Soft Matter

A versatile method for the selective core-crosslinking of hyaluronic acid nanogels via ketone-hydrazide chemistry: from chemical characterization to in vivo biodistribution

scientific article published on 01 June 2018

Acid-Labile Thermoresponsive Copolymers That Combine Fast pH-Triggered Hydrolysis and High Stability under Neutral Conditions

scientific article published on 24 July 2015

Acrylamides with hydrolytically labile carbonate ester side chains as versatile building blocks for well-defined block copolymer micelles via RAFT polymerization

Amphiphilic Ferrocene-Containing PEG Block Copolymers as Micellar Nanocarriers and Smart Surfactants

scientific article

Anisotropic multicompartment micro- and nano-capsules produced via embedding into biocompatible PLL/HA films

scientific article published in 2011

Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide

scientific article published on 24 April 2017

Biocatalytically Active Thin Films via Self-Assembly of 2-Deoxy-d-ribose-5-phosphate Aldolase-Poly(N-isopropylacrylamide) Conjugates

scientific article published on 28 November 2017

Biodegradable microcapsules designed via 'click' chemistry

scientific article published on 14 November 2007

Biodegradable polyelectrolyte microcapsules: antigen delivery tools with Th17 skewing activity after pulmonary delivery

scientific article published on 30 November 2009

Biomaterials applications of cyclic polymers

scientific article published on 19 October 2020

Cancer Cell Lysate Entrapment in CaCO3 Engineered with Polymeric TLR-Agonists: Immune-Modulating Microparticles in View of Personalized Antitumor Vaccination

Cancer nanomedicine meets immunotherapy: opportunities and challenges

scientific article published on 17 June 2020

Cell surface clicking of antibody-recruiting polymers to metabolically azide-labeled cancer cells

scientific article published on 01 September 2019

Colorimetric Logic Gates Based on Poly(2-alkyl-2-oxazoline)-Coated Gold Nanoparticles

article

Complexity from Simplicity: Unique Polymer Capsules, Rods, Monoliths, and Liquid Marbles Prepared via HIPE in Microfluidics

Connexin32 hemichannels contribute to the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death

scientific article published on 4 December 2009

Control over Imidazoquinoline Immune Stimulation by pH-Degradable Poly(norbornene) Nanogels

scientific article published on 07 April 2020

Core/shell protein-reactive nanogels via a combination of RAFT polymerization and vinyl sulfone postmodification

scientific article published on 15 September 2016

Correction to Engineering Strategies for Lymph Node Targeted Immune Activation

scientific article published on 18 November 2020

Coumarin-containing thermoresponsive hyaluronic acid-based nanogels as delivery systems for anticancer chemotherapy

scientific article published on 14 August 2017

Covalent Cell Surface Conjugation of Nanoparticles by a Combination of Metabolic Labeling and Click Chemistry

scientific article published in 2021

Crossing the barrier: Targeting epithelial receptors for enhanced oral vaccine delivery.

scientific article published on 13 February 2012

Degradable Multilayer Films and Hollow Capsules via a ‘Click’ Strategy

Degradable ketal-based block copolymer nanoparticles for anticancer drug delivery: a systematic evaluation

scientific article

Delivering the goods

Delivering the goods

Design of pH-Degradable Polymer-Lipid Amphiphiles Using a Ketal-Functionalized RAFT Chain Transfer Agent

scientific article published on 10 March 2020

Designing hyaluronic acid-based layer-by-layer capsules as a carrier for intracellular drug delivery.

scientific article

Designing oral vaccines targeting intestinal dendritic cells ⬇️

scientific article published on 05 March 2011

Designing polymeric particles for antigen delivery

scientific article

Developments and future clinical outlook of taxane nanomedicines

scientific article published on 20 March 2017

Dual pH- and temperature-responsive RAFT-based block co-polymer micelles and polymer–protein conjugates with transient solubility

article

Duality of β-glucan microparticles: antigen carrier and immunostimulants.

scientific article published on 31 May 2016

ER stress in antigen-presenting cells promotes NKT cell activation through endogenous neutral lipids

scientific article published on 03 May 2020

Efficient Innate Immune Killing of Cancer Cells Triggered by Cell-Surface Anchoring of Multivalent Antibody-Recruiting Polymers

scientific article published on 19 July 2019

Engineered 3D microporous gelatin scaffolds to study cell migration

scientific article published on 29 February 2012

Engineering Polymer Hydrogel Nanoparticles for Lymph Node-Targeted Delivery

scientific article

Engineering Strategies for Lymph Node Targeted Immune Activation

scientific article published on 10 September 2020

Enhanced Permeability and Retention-like Extravasation of Nanoparticles from the Vasculature into Tuberculosis Granulomas in Zebrafish and Mouse Models

scientific article published on 15 August 2018

FRET Monitoring of Intracellular Ketal Hydrolysis in Synthetic Nanoparticles

scientific article published on 25 July 2018

Facile Two‐Step Synthesis of Porous Antigen‐Loaded Degradable Polyelectrolyte Microspheres ⬇️

scientific article published on November 8, 2010

Fast and accurate partial hydrolysis of poly(2-ethyl-2-oxazoline) into tailored linear polyethylenimine copolymers

Feasibility of Mechanical Extrusion to Coat Nanoparticles with Extracellular Vesicle Membranes

scientific article published on 29 July 2020

Fusing Antigens and Adjuvants into Traceless Nanogels

scientific article published on 06 March 2020

Gelucire 44/14 based immediate release formulations for poorly water-soluble drugs ⬇️

scientific article published on August 8, 2012

Glucose-responsive polyelectrolyte capsules

scientific article published in May 2006

Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo.

scientific article published on 23 December 2017

Highly Versatile Approach for Preparing Functional Hybrid Multisegmented Nanotubes and Nanowires

Hyaluronic Acid Conjugates of TLR7/8 Agonists for Targeted Delivery to Secondary Lymphoid Tissue

scientific article published on 17 July 2018

Hydrogen bonded multilayer films based on poly(2-oxazoline)s and tannic acid

scientific article published in October 2014

Hydrogen bonded polymeric multilayer films assembled below and above the cloud point temperature

scientific article published in October 2013

Hydrophobic shell loading of biopolyelectrolyte capsules

scientific article published on 17 May 2011

Immunoengineering through cancer vaccines - A personalized and multi-step vaccine approach towards precise cancer immunity

Immunoengineering through cancer vaccines – A personalized and multi-step vaccine approach towards precise cancer immunity

Improved anti-inflammatory effects in rabbit eye model using biodegradable poly beta-amino ester nanoparticles of triamcinolone acetonide

scientific article published on 15 August 2013

Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction

scientific article published on 05 December 2018

Interaction between polymeric multilayer capsules and immune cells ⬇️

scientific article published on 06 March 2012

Just spray it--LbL assembly enters a new age.

scientific article

Layer-by-layer coated digitally encoded microcarriers for quantification of proteins in serum and plasma

scientific article published on 4 December 2007

Layer-by-layer incorporation of growth factors in decellularized aortic heart valve leaflets

scientific article published in April 2010

Linear polyethylenimine as (multi) functional initiator for organocatalytic l-lactide polymerization

scientific article published on 27 November 2014

Lymph node targeted immune-activation by engineered block copol-ymer amphiphiles - TLR7/8 agonist conjugates

scientific article published in 2018

Magnetically engineered microcapsules as intracellular anchors for remote control over cellular mobility

scientific article published on 12 September 2013

Mechanical strength and intracellular uptake of CaCO3-templated LbL capsules composed of biodegradable polyelectrolytes: the influence of the number of layers

scientific article published on 10 January 2013

Micellar Paclitaxel-Initiated RAFT Polymer Conjugates with Acid-Sensitive Behavior

Microcapsules ejecting nanosized species into the environment

scientific article

Mobility of model proteins in hydrogels composed of oppositely charged dextran microspheres studied by protein release and fluorescence recovery after photobleaching

scientific article

Modular core-shell polymeric nanoparticles mimicking viral structures for vaccination

scientific article published on 11 November 2018

Molecular Imaging for Cancer Immunotherapy: Seeing Is Believing

scientific article published on 27 January 2020

Mucosal irritation potential of polyelectrolyte multilayer capsules

scientific article published on 3 December 2010

Multifunctional layer-by-layer coating of digitally encoded microparticles

scientific article

Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

scholarly article by Behrouz Hassannia et al published 1 August 2018 in Journal of Clinical Investigation

Nanomedicine and cancer immunotherapy

scientific article published on 28 May 2020

Nanomedicine and macroscale materials in immuno-oncology

scientific article published on 01 January 2019

Nanomedicine-mediated alteration of the pharmacokinetic profile of small molecule cancer immunotherapeutics

scientific article published on 25 May 2020

Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses

Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses

Nanoporous Hydrogen Bonded Polymeric Microparticles: Facile and Economic Production of Cross Presentation Promoting Vaccine Carriers

Nanoporous polyelectrolyte vaccine microcarriers. A formulation platform for enhancing humoral and cellular immune responses

scientific article published on 28 July 2014

One-Pot Preparation of Inert Well-Defined Polymers by RAFT Polymerization and In Situ End Group Transformation

scientific article published on 2 April 2015

One-step spray-dried polyelectrolyte microparticles enhance the antigen cross-presentation capacity of porcine dendritic cells

scientific article published on December 2012

Partial hydrolysis of poly(2-ethyl-2-oxazoline) and potential implications for biomedical applications?

scientific article published on 6 July 2012

Poly(2-ethyl-2-oxazoline) Conjugates with Salicylic Acid via Degradable Modular Ester Linkages

scientific article published on 08 July 2020

Poly(2-ethyl-2-oxazoline) as matrix excipient for drug formulation by hot melt extrusion and injection molding

scientific article published on 14 August 2012

Poly(2-methyl-2-oxazoline) conjugates with doxorubicin: From synthesis of high drug loading water-soluble constructs to in vitro anti-cancer properties

scientific article published on 18 June 2020

Poly(N-isopropylacrylamide) coated gold nanoparticles as colourimetric temperature and salt sensors

Polyelectrolyte microcapsules as antigen delivery vehicles to dendritic cells: uptake, processing, and cross-presentation of encapsulated antigens

scientific article published in January 2009

Polyelectrolyte-Enrobed Cancer Cells in View of Personalized Immune-Therapy

scientific article

Polymer Capsules: Versatile Loading of Diverse Cargo into Functional Polymer Capsules (Adv. Sci. 1‐2/2015).

scientific article published on 13 February 2015

Polymeric microcapsules with light responsive properties for encapsulation and release

scientific article published on 03 August 2009

Polymeric multilayer capsule-mediated vaccination induces protective immunity against cancer and viral infection

scientific article published on 13 February 2012

Polymeric multilayer capsules for drug delivery

scientific article published on 26 January 2012

Polymeric multilayer capsules in drug delivery

scientific article published on September 2010

Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties

scientific article published on 15 June 2018

Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists

scientific article published on 12 September 2019

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist

scientific article

Preparation and Characterization of Alginate Microparticles Containing a Model Protein for Oral Administration in Gnotobiotic European Sea Bass (Dicentrarchus labrax) Larvae

scientific article

Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(beta-amino esters).

scientific article

Prolonged innate immune activation by enzyme-sensitive imidazoquinoline TLR7/8 agonist prodrug vesicles

scientific article published on 11 June 2020

Pulsed drug delivery

scientific article

Pulsed in vitro release and in vivo behavior of exploding microcapsules

scientific article published on 3 February 2009

Rational design of a hexapeptide hydrogelator for controlled-release drug delivery

scientific article published on 02 December 2014

Recombinant DnaK Orally Administered Protects Axenic European Sea Bass Against Vibriosis

scientific article published on 01 January 2019

Recombinant ferritin-H induces immunosuppression in European sea bass larvae (Dicentrarchus labrax) rather than immunostimulation and protection against a Vibrio anguillarum infection

scientific article published on 13 September 2018

Redox-responsive degradable PEG cryogels as potential cell scaffolds in tissue engineering

scientific article published on 4 January 2012

Release Properties of Pressurized Microgel Templated Capsules

Release mechanisms for polyelectrolyte capsules

scientific article published on 13 October 2006

Salt Plays a Pivotal Role in the Temperature-Responsive Aggregation and Layer-by-Layer Assembly of Polymer-Decorated Gold Nanoparticles

article published in 2013

Salt-Driven Deposition of Thermoresponsive Polymer-Coated Metal Nanoparticles on Solid Substrates

scientific article published on 3 May 2016

Self-exploding lipid-coated microgels.

scientific article published in January 2006

Sequence-selective DNA recognition and enhanced cellular up-take by peptide-steroid conjugates.

scientific article

Single-step formation of degradable intracellular biomolecule microreactors

scientific article published on August 25, 2011

Solvent-free drug crystal engineering for drug nano- and micro suspensions ⬇️

scientific article published on November 3, 2012

Solvent-free mechanochemical synthesis of a bicyclononyne tosylate: a fast route towards bioorthogonal clickable poly(2-oxazoline)s

Spontaneous Protein Adsorption on Graphene Oxide Nanosheets Allowing Efficient Intracellular Vaccine Protein Delivery

scientific article published on 22 December 2015

Spray-dried polyelectrolyte microparticles in oral antigen delivery: stability, biocompatibility, and cellular uptake.

scientific article published on 14 May 2014

Squaric ester amides as hydrolysis-resistant functional groups for protein-conjugation of RAFT-derived polymers

Stapling monomeric GCN4 peptides allows for DNA binding and enhanced cellular uptake.

scientific article published on April 2015

Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine

scientific article published on 23 October 2020

Straightforward RAFT procedure for the synthesis of heterotelechelic poly(acrylamide)s

scientific article

Structural modifications of polymethacrylates: impact on thermal behavior and release characteristics of glassy solid solutions

scientific article published on 26 February 2013

Super Resolution Imaging of Nanoparticles Cellular Uptake and Trafficking

scientific article

Surface-engineered polyelectrolyte multilayer capsules: synthetic vaccines mimicking microbial structure and function

scientific article published on 12 March 2012

Synthesis of monodisperse biodegradable microgels in microfluidic devices

scientific article published in November 2005

Synthetic Rhamnose Glycopolymer Cell-Surface Receptor for Endogenous Antibody Recruitment

scientific article published on 08 January 2020

Tailoring Cellular Uptake of Gold Nanoparticles Via the Hydrophilic-to-Hydrophobic Ratio of their (Co)polymer Coating

Targeting Protumoral Tumor-Associated Macrophages with Nanobody-Functionalized Nanogels through Strain Promoted Azide Alkyne Cycloaddition Ligation

scientific article published on 28 June 2018

The Future of Layer-by-Layer Assembly: A Tribute to ACS Nano Associate Editor Helmuth Möhwald

scientific article published on 24 May 2019

The pros and cons of polyelectrolyte capsules in drug delivery

scientific article published on June 2009

The relevance of shear, sedimentation and diffusion during spin freezing, as potential first step of a continuous freeze-drying process for unit doses

scientific article published on 21 January 2018

Thermally Induced Charge Reversal of Layer-by-Layer Assembled Single-Component Polymer Films

scientific article published on 08 March 2016

Thermoresponsive hyaluronic acid nanogels as hydrophobic drug carrier to macrophages.

scientific article

Thermoresponsive polymer coated gold nanoparticles: from MADIX/RAFT copolymerization of N-vinylpyrrolidone and N-vinylcaprolactam to salt and temperature induced nanoparticle aggregation

scholarly article in RSC Advances, vol. 5 no. 53, 2015

Transient Multivalent Nanobody Targeting to CD206-Expressing Cells via PH-Degradable Nanogels

scientific article published on 01 October 2020

Transiently Responsive Block Copolymer Micelles Based on N-(2-Hydroxypropyl)methacrylamide Engineered with Hydrolyzable Ethylcarbonate Side Chains

scientific article published on 9 December 2015

Transiently Thermoresponsive Acetal Polymers for Safe and Effective Administration of Amphotericin B as a Vaccine Adjuvant.

scientific article published on 26 November 2017

Transiently thermoresponsive polymers and their applications in biomedicine.

scientific article published on 6 February 2017

Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells.

scientific article published on 2 April 2015

Tunable self-assembled nanogels composed of well-defined thermoresponsive hyaluronic acid–polymer conjugates

scientific article published on 09 July 2013

Tyrosine-Triazolinedione Bioconjugation as Site-Selective Protein Modification Starting from RAFT-Derived Polymers

Ultrasound-responsive polymer-coated microbubbles that bind and protect DNA.

scientific article published in August 2006

Ultrasound-triggered release from multilayered capsules

scientific article

Unexpected Reactivity Switch in the Statistical Copolymerization of 2-Oxazolines and 2-Oxazines Enabling the One-Step Synthesis of Amphiphilic Gradient Copolymers

scientific article published on 10 June 2019

Uptake of Long Protein-Polyelectrolyte Nanotubes by Dendritic Cells.

scientific article published on 13 November 2017

Use of endospore-forming bacteria as an active oxygen scavenger in plastic packaging materials

article

Versatile Loading of Diverse Cargo into Functional Polymer Capsules

scientific article published on 29 January 2015

Well-Defined Polymer-Paclitaxel Prodrugs by a Grafting-from-Drug Approach

scientific article published on 25 August 2016

Zebrafish Embryos Allow Prediction of Nanoparticle Circulation Times in Mice and Facilitate Quantification of Nanoparticle-Cell Interactions

scientific article published on 15 January 2020

pH-Degradable Mannosylated Nanogels for Dendritic Cell Targeting

scientific article

pH-Sensitive Hydrazone-Linked Doxorubicin Nanogels via Polymeric-Activated Ester Scaffolds: Synthesis, Assembly, and In Vitro and In Vivo Evaluation in Tumor-Bearing Zebrafish

pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation

scientific article published on 05 July 2016

pH-independent immediate release polymethacrylate formulations--an observational study

scientific article published on 22 June 2015

β-Glucan microparticles are good candidates for mucosal antigen delivery in oral vaccination.

scientific article

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