List of works - Wendy K. Alderton

Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae.

scientific article published in August 2010

Affinity labeling of recombinant ricin A chain with Procion blue MX-R.

scientific article published in November 1995

Colorectal cancer ascertainment through cancer registries, hospital episode statistics, and self-reporting compared to confirmation by clinician: A cohort study nested within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

scientific article published in February 2019

Current and Future Perspectives in Psychiatric Drug Discovery.

scientific article published on July 2009

Designer dyes: 'biomimetic' ligands for the purification of pharmaceutical proteins by affinity chromatography

scientific article

Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects

scientific article

Evaluation of serum CEA, CYFRA21-1 and CA125 for the early detection of colorectal cancer using longitudinal preclinical samples.

scientific article published on 2 June 2015

Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor

scientific article published on 21 March 2011

Kinetics of CO binding to the haem domain of murine inducible nitric oxide synthase: differential effects of haem domain ligands

scientific article

Mode of action of (R)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine against herpesviruses

scientific article

Nitric oxide synthases: structure, function and inhibition

scientific article (publication date: August 2001)

Nitroarginine and tetrahydrobiopterin binding to the haem domain of neuronal nitric oxide synthase using a scintillation proximity assay.

scientific article published on May 1998

Scintillation proximity assay to measure nitroarginine and tetrahydrobiopterin binding to heme domain of neuronal nitric oxide synthase

scientific article published on 01 January 1999

The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer

scientific article

Validation of the use of zebrafish larvae in visual safety assessment.

scientific article published on 2 May 2008

Zebrafish based assays for the assessment of cardiac, visual and gut function--potential safety screens for early drug discovery

scientific article published on 08 June 2008

Zebrafish: an emerging technology for in vivo pharmacological assessment to identify potential safety liabilities in early drug discovery.

scientific article

List of works by Wendy K. Alderton

Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae.

Affinity labeling of recombinant ricin A chain with Procion blue MX-R.

Colorectal cancer ascertainment through cancer registries, hospital episode statistics, and self-reporting compared to confirmation by clinician: A cohort study nested within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

Current and Future Perspectives in Psychiatric Drug Discovery.

Designer dyes: 'biomimetic' ligands for the purification of pharmaceutical proteins by affinity chromatography

Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects

Evaluation of serum CEA, CYFRA21-1 and CA125 for the early detection of colorectal cancer using longitudinal preclinical samples.

Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor

Kinetics of CO binding to the haem domain of murine inducible nitric oxide synthase: differential effects of haem domain ligands

Mode of action of (R)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine against herpesviruses

Nitric oxide synthases: structure, function and inhibition

Nitroarginine and tetrahydrobiopterin binding to the haem domain of neuronal nitric oxide synthase using a scintillation proximity assay.

Scintillation proximity assay to measure nitroarginine and tetrahydrobiopterin binding to heme domain of neuronal nitric oxide synthase

The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer

Validation of the use of zebrafish larvae in visual safety assessment.

Zebrafish based assays for the assessment of cardiac, visual and gut function--potential safety screens for early drug discovery

Zebrafish: an emerging technology for in vivo pharmacological assessment to identify potential safety liabilities in early drug discovery.