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List of works by Jorge C Blanco

A Recombinant Respiratory Syncytial Virus Vaccine Candidate Attenuated by a Low-Fusion F Protein Is Immunogenic and Protective against Challenge in Cotton Rats

scientific article published on 08 June 2016

A cotton rat model of human parainfluenza 3 laryngotracheitis: virus growth, pathology, and therapy.

scientific article

A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation

scientific article

A multifaceted approach to RSV vaccination

scholarly article by Jorge C G Blanco et al published 3 July 2018 in Human Vaccines & Immunotherapeutics

A recombinant anchorless respiratory syncytial virus (RSV) fusion (F) protein/monophosphoryl lipid A (MPL) vaccine protects against RSV-induced replication and lung pathology.

scientific article

Activation of interferon response through toll-like receptor 3 impacts viral pathogenesis and pulmonary toll-like receptor expression during respiratory syncytial virus and influenza infections in the cotton rat Sigmodon hispidus model

scientific article

Age-related differences in pulmonary cytokine response to respiratory syncytial virus infection: modulation by anti-inflammatory and antiviral treatment

scientific article published on 4 January 2007

Agents that increase AAM differentiation blunt RSV-mediated lung pathology

scientific article

Alternative Virus-Like Particle-Associated Prefusion F Proteins as Maternal Vaccines for Respiratory Syncytial Virus

scientific article published on 13 November 2019

Analysis of TLR4 polymorphic variants: new insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling

scientific article published on July 2006

Association of TLR4 polymorphisms with symptomatic respiratory syncytial virus infection in high-risk infants and young children

scientific article published on September 2007

Characterization of late tuberculosis infection in Sigmodon hispidus.

scientific article published on 15 February 2009

Chronic helminth infection does not exacerbate Mycobacterium tuberculosis infection

scientific article

Cloning of repetitive DNA sequences from Toxoplasma gondii and their usefulness for parasite detection.

scientific article

Co-infection of the cotton rat (Sigmodon hispidus) with Staphylococcus aureus and influenza A virus results in synergistic disease.

scientific article

Comparisons of Antibody Populations in Different Pre-Fusion F VLP-Immunized Cotton Rat Dams and Their Offspring

scientific article published on 18 March 2020

Cotton rat immune responses to virus-like particles containing the pre-fusion form of respiratory syncytial virus fusion protein.

scientific article

Cotton rat lung transcriptome reveals host immune response to Respiratory Syncytial Virus infection

scientific article published in Scientific Reports

Cotton rat model for testing vaccines and antivirals against respiratory syncytial virus.

scientific article

Cytokine and chemokine gene expression after primary and secondary respiratory syncytial virus infection in cotton rats

scientific article

Early diagnosis of toxoplasmic encephalitis in AIDS patients by dot blot hybridization analysis.

scientific article published on December 1992

Effect of aging on immunogenicity and efficacy of inactivated influenza vaccines in cotton rats Sigmodon hispidus

scientific article published on 02 July 2020

Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model.

scientific article published on 15 May 2018

Efficacy of the Herpes Simplex Virus 2 (HSV-2) Glycoprotein D/AS04 Vaccine against Genital HSV-2 and HSV-1 Infection and Disease in the Cotton Rat Sigmodon hispidus Model.

scientific article

Enterovirus D-68 Infection, Prophylaxis, and Vaccination in a Novel Permissive Animal Model, the Cotton Rat (Sigmodon hispidus).

scientific article

Epigenetic Mechanisms Governing Innate Inflammatory Responses.

scientific article

Evaluation of the potential effects of AS03-adjuvanted A(H1N1)pdm09 vaccine administration on the central nervous system of non-primed and A(H1N1)pdm09-primed cotton rats

scientific article

Expression of Human CD4 and chemokine receptors in cotton rat cells confers permissiveness for productive HIV infection.

scientific article published on 14 May 2009

Herpes Simplex Virus 1 Induces Brain Inflammation and Multifocal Demyelination in the Cotton Rat Sigmodon hispidus

scientific article published on 12 December 2019

Human metapneumovirus: enhanced pulmonary disease in cotton rats immunized with formalin-inactivated virus vaccine and challenged.

scientific article published on 15 May 2007

Immunization with Live Human Rhinovirus (HRV) 16 Induces Protection in Cotton Rats against HRV14 Infection

scientific article published on 31 August 2017

Inactivation of respiratory syncytial virus by zinc finger reactive compounds.

scientific article

Induction of type I interferons and interferon-inducible Mx genes during respiratory syncytial virus infection and reinfection in cotton rats.

scientific article published on January 2008

Inhibition of ligand induced promoter occupancy in vivo by a dominant negative RXR

scientific article published on 01 February 1996

Interaction between the retinoid X receptor and transcription factor IIB is ligand-dependent in vivo

scientific article published on 01 January 1998

Interferon-inducible Mx gene expression in cotton rats: cloning, characterization, and expression during influenza viral infection

scientific article published on 01 December 2006

Limited role of ceramide in lipopolysaccharide-mediated mitogen-activated protein kinase activation, transcription factor induction, and cytokine release

scientific article published on 01 April 1999

Maternal transfer of RSV immunity in cotton rats vaccinated during pregnancy

scientific article published on 31 August 2015

Methods for monitoring dynamics of pulmonary RSV replication by viral culture and by real-time reverse transcription-PCR in vivo: Detection of abortive viral replication.

scientific article published on March 2010

Modeling Human Respiratory Viral Infections in the Cotton Rat (Sigmodon hispidus).

scientific article

Mutations in the 1,25-dihydroxyvitamin D3 receptor identifying C-terminal amino acids required for transcriptional activation that are functionally dissociated from hormone binding, heterodimeric DNA binding, and interaction with basal transcription

scientific article published on June 1997

New insights for development of a safe and protective RSV vaccine

scientific article

Novel drugs targeting Toll-like receptors for antiviral therapy

scientific article

Novel strategies for targeting innate immune responses to influenza.

scientific article published on 27 January 2016

PROPHYLACTIC ANTIBODY TREATMENT AND INTRAMUSCULAR IMMUNIZATION REDUCE INFECTIOUS HUMAN RHINOVIRUS 16 LOAD IN THE LOWER RESPIRATORY TRACT OF CHALLENGED COTTON RATS.

scientific article

Pathogenesis of human metapneumovirus lung infection in BALB/c mice and cotton rats

scientific article published on July 2005

Preclinical assessment of safety of maternal vaccination against respiratory syncytial virus (RSV) in cotton rats.

scientific article published on 14 June 2017

Prospects of antiviral and anti-inflammatory therapy for respiratory syncytial virus infection

scientific article

Receptor characterization and susceptibility of cotton rats to avian and 2009 pandemic influenza virus strains

scientific article

Repetitive DNA sequences of Toxoplasma gondii for development of diagnostic probes

scientific article published on 01 October 1991

Respiratory syncytial virus (RSV) infection induces cyclooxygenase 2: a potential target for RSV therapy.

scientific article published in April 2005

Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2.

scientific article

Respiratory syncytial virus infects and abortively replicates in the lungs in spite of preexisting immunity

scientific article

Retinoid receptor-induced alteration of the chromatin assembled on a ligand-responsive promoter in Xenopus oocytes.

scientific article published in March 1998

Role of the lipoxygenase pathway in RSV-induced alternatively activated macrophages leading to resolution of lung pathology.

scientific article published on 25 September 2013

Serum High-Mobility-Group Box 1 as a Biomarker and a Therapeutic Target during Respiratory Virus Infections

scientific article published on 13 March 2018

Species-specific transcriptomic changes upon respiratory syncytial virus infection in cotton rats

scientific article published in 2022

TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection.

scientific article published on 20 January 2017

The American cotton rat: a novel model for pulmonary tuberculosis

scientific article published on 12 September 2006

The TLR4 agonist, monophosphoryl lipid A, attenuates the cytokine storm associated with respiratory syncytial virus vaccine-enhanced disease.

scientific article published on 18 April 2006

The TLR4 antagonist Eritoran protects mice from lethal influenza infection

scientific article published on May 2013

The anti-tumor agent, 5,6-dimethylxanthenone-4-acetic acid (DMXAA), induces IFN-beta-mediated antiviral activity in vitro and in vivo

scientific article

The antiviral potential of interferon-induced cotton rat Mx proteins against orthomyxovirus (influenza), rhabdovirus, and bunyavirus.

scientific article published on October 2007

The cotton rat Sigmodon hispidus model of respiratory syncytial virus infection.

scientific article published on January 2013

The cotton rat model of respiratory viral infections

scientific article published on 25 April 2009

The cotton rat provides a useful small-animal model for the study of influenza virus pathogenesis.

scientific article

The cotton rat: an underutilized animal model for human infectious diseases can now be exploited using specific reagents to cytokines, chemokines, and interferons.

scientific article

The histone acetylase PCAF is a nuclear receptor coactivator.

scientific article

The role of the interferon regulatory factors, IRF-1 and IRF-2, in LPS-induced cyclooxygenase-2 (COX-2) expression in vivo and in vitro

scientific article published on 01 January 2002

Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription.

scientific article

Treatment with novel RSV Ig RI-002 controls viral replication and reduces pulmonary damage in immunocompromised Sigmodon hispidus

scientific article published on 14 September 2015

[Monoclonal antibodies against Toxoplasma gondii for the histopathologic diagnosis of toxoplasmosis]

scientific article published on 01 January 1991

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