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List of works by Hans Henrik Gad

2'3'-cGAMP triggers a STING- and NF-κB-dependent broad antiviral response in <i>Drosophila</i>

scientific article published on 01 December 2020

A conserved sugar bridge connected to the WSXWS motif has an important role for transport of IL-21R to the plasma membrane.

scientific article

Defective RNA sensing by RIG-I in severe influenza virus infection

scientific article published on 17 February 2018

Defective interferon priming and impaired antiviral responses in a patient with an IRF7 variant and severe influenza

scientific article published on 06 June 2019

Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

scientific article

Human interferon-lambda3 is a potent member of the type III interferon family.

scientific article

IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission.

scientific article

IFNλ is a potent anti-influenza therapeutic without the inflammatory side effects of IFNα treatment.

scientific article published on 11 August 2016

Identification of an IRF3 variant and defective antiviral interferon responses in a patient with severe influenza

scientific article published on 01 November 2019

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses.

scientific article published on 19 February 2016

Inhibition of SARS-CoV-2 by type I and type III interferons

scientific article published on 25 June 2020

Interferon-  Is Functionally an Interferon but Structurally Related to the Interleukin-10 Family

scientific article

Interferon-λ enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin

scientific article published on 18 March 2019

Lambda Interferons: New Cytokines with Old Functions

scientific article

Length dependent activation of OAS proteins by dsRNA

scientific article published on 17 October 2019

Mapping of Chikungunya virus interactions with host proteins identified nsP2 as a highly connected viral component

scientific article published on 18 January 2012

Rapid Uptake and Inhibition of Viral Propagation by Extracellular OAS1.

scientific article published on 17 December 2014

Selection of a Novel and Highly Specific Tumor Necrosis Factor   (TNF ) Antagonist: INSIGHT FROM THE CRYSTAL STRUCTURE OF THE ANTAGONIST-TNF  COMPLEX

scientific article

Species Specificity of Type III Interferon Activity and Development of a Sensitive Luciferase-Based Bioassay for Quantitation of Mouse Interferon-λ

scientific article published on 18 October 2018

Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling

scientific article published on 29 April 2015

The 2'-5'-oligoadenylate synthetase 3 enzyme potently synthesizes the 2'-5'-oligoadenylates required for RNase L activation.

scientific article published on October 2014

The IFNL4 Gene Is a Noncanonical Interferon Gene with a Unique but Evolutionarily Conserved Regulation

scientific article published on 14 February 2020

The Influence of the rs30461 Single Nucleotide Polymorphism on IFN-λ1 Activity and Secretion

scientific article published on 22 May 2019

The interferon-stimulated gene product oligoadenylate synthetase-like protein enhances replication of Kaposi's sarcoma-associated herpesvirus (KSHV) and interacts with the KSHV ORF20 protein. ⬇️

scientific article published on 2 March 2018

The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities

scientific article

The structure of human interferon lambda and what it has taught us.

scientific article published on August 2010

Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells.

scientific article

Type I and III interferons disrupt lung epithelial repair during recovery from viral infection

scientific article

Type I and Type III Interferons Differ in Their Adjuvant Activities for Influenza Vaccines

scientific article published on 13 November 2019

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