Search filters

List of works by Suresh Mahalingam

Alphavirus-induced hyperactivation of PI3K/AKT directs pro-viral metabolic changes.

scientific article published on 29 January 2018

Amelioration of alphavirus-induced arthritis and myositis in a mouse model by treatment with bindarit, an inhibitor of monocyte chemotactic proteins

scientific article

An updated review of avian-origin Tembusu virus: a newly emerging avian Flavivirus

scientific article published on 6 September 2017

Applications of animal models of infectious arthritis in drug discovery: a focus on alphaviral disease

scientific article published on June 2011

Approaches to the treatment of disease induced by chikungunya virus

scientific article

Arthritogenic alphaviral infection perturbs osteoblast function and triggers pathologic bone loss

scientific article

Arthritogenic alphaviruses: new insights into arthritis and bone pathology

scientific article

Arthropod-borne arthritides

scientific article published on April 2015

Attenuation and Stability of CHIKV-NoLS, a Live-Attenuated Chikungunya Virus Vaccine Candidate

scientific article published on 22 December 2018

Bindarit, an inhibitor of monocyte chemotactic protein synthesis, protects against bone loss induced by chikungunya virus infection

scientific article

Call to action for dengue vaccine failure

scientific article published on August 2013

Changes in complement alternative pathway components, factor B and factor H during dengue virus infection in the AG129 mouse

scientific article published on 07 January 2021

Characterization of Barmah Forest virus pathogenesis in a mouse model.

scientific article published on 16 June 2014

Characterization of Ross River virus tropism and virus-induced inflammation in a mouse model of viral arthritis and myositis

scientific article

Chikungunya Virus Arthritis: Implications of Acute and Chronic Inflammation Mechanisms on Patient Management

scientific article published on 29 December 2017

Chikungunya virus and arthritic disease

scientific article

Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen

scientific article

Chikungunya virus: emerging targets and new opportunities for medicinal chemistry

scientific article

Chikungunya: a re-emerging virus

scientific article

Chikungunya: vaccines and therapeutics

scientific article published on 8 December 2017

Complement contributes to inflammatory tissue destruction in a mouse model of Ross River virus-induced disease

scientific article

Correction for Chen et al., Bindarit, an Inhibitor of Monocyte Chemotactic Protein Synthesis, Protects against Bone Loss Induced by Chikungunya Virus Infection

scientific article published in December 2015

Critical role for macrophage migration inhibitory factor (MIF) in Ross River virus-induced arthritis and myositis

scientific article

Cytotoxic T-lymphocyte epitope vaccination protects against human metapneumovirus infection and disease in mice

scientific article

Decreased Virulence of Ross River Virus Harboring a Mutation in the First Cleavage Site of Nonstructural Polyprotein Is Caused by a Novel Mechanism Leading to Increased Production of Interferon-Inducing RNAs

scientific article published on 21 August 2018

Dengue vaccine efficacy trial: does interference cause failure?

scientific article published on March 2013

Dengue virus and host antibody: a dangerous balancing act.

scientific article published on 23 July 2014

Dengue virus therapeutic intervention strategies based on viral, vector and host factors involved in disease pathogenesis.

scientific article published on 26 October 2012

Development of vaccines for SARS-CoV-2

scientific article published on 17 August 2020

Differential Induction of Type I Interferon Responses in Myeloid Dendritic Cells by Mosquito and Mammalian-Cell-Derived Alphaviruses

scientific article

Disease exacerbation by etanercept in a mouse model of alphaviral arthritis and myositis

scientific article published in February 2011

Downregulation of interferon-β in antibody-dependent enhancement of dengue viral infections of human macrophages is dependent on interleukin-6.

scientific article published in August 2011

Dual proinflammatory and antiviral properties of pulmonary eosinophils in respiratory syncytial virus vaccine-enhanced disease.

scientific article

Effects of an In-Frame Deletion of the 6k Gene Locus from the Genome of Ross River Virus

scientific article published on 10 February 2016

Emergent chikungunya virus and arthritis in the Americas

scientific article published in September 2015

Enhancement of Zika Infection by Dengue Virus-Specific Antibody Is Associated With Low Levels of Antiviral Factors

scientific article published on September 2017

Eosinophils contribute to innate antiviral immunity and promote clearance of respiratory syncytial virus

scientific article

Fc receptors in antibody-dependent enhancement of viral infections

scientific article

Fighting back against chikungunya

scientific article published on 2 March 2015

Flaviviridae virus nonstructural proteins 5 and 5A mediate viral immune evasion and are promising targets in drug development

scientific article

Hendra virus: an emerging paramyxovirus in Australia

scientific article published on 24 August 2012

Heterogeneity of clinical isolates of chikungunya virus and its impact on the responses of primary human fibroblast-like synoviocytes

scientific article

Human Metapneumovirus Infection in Chronic Obstructive Pulmonary Disease: Impact of Glucocorticosteroids and Interferon

scientific article published on 4 April 2017

Human metapneumovirus establishes persistent infection in the lungs of mice and is reactivated by glucocorticoid treatment.

scientific article published on 08 April 2009

IL-3 and CSF-1 interact to promote generation of CD11c+ IL-10-producing macrophages

scientific article

Identification and characterization of a ross river virus variant that grows persistently in macrophages, shows altered disease kinetics in a mouse model, and exhibits resistance to type I interferon

scientific article

Identification of Natural Molecular Determinants of Ross River Virus Type I Interferon Modulation

scientific article published on 31 March 2020

Inhibition of Interleukin-1β Signaling by Anakinra Demonstrates a Critical Role of Bone Loss in Experimental Arthritogenic Alphavirus Infections

scientific article published on 06 June 2019

Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness

scientific article published in October 2006

Interleukin 6, RANKL, and osteoprotegerin expression by chikungunya virus-infected human osteoblasts

scientific article published on 25 May 2012

Interleukin-17 contributes to Ross River virus-induced arthritis and myositis

scientific article published on 10 February 2022

Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes

scientific article

Lower temperatures reduce type I interferon activity and promote alphaviral arthritis

scientific article published on 27 December 2017

Macrophage migration inhibitory factor receptor CD74 mediates alphavirus-induced arthritis and myositis in murine models of alphavirus infection

scientific article published on October 2013

Macrophage-derived proinflammatory factors contribute to the development of arthritis and myositis after infection with an arthrogenic alphavirus

scientific article

Mannose binding lectin is required for alphavirus-induced arthritis/myositis

scientific article

Methotrexate treatment causes early onset of disease in a mouse model of Ross River virus-induced inflammatory disease through increased monocyte production

scientific article (publication date: 2013)

MicroRNA Regulation of Human Genes Essential for Influenza A (H7N9) Replication

scientific article

Modulation of Monocyte-Driven Myositis in Alphavirus Infection Reveals a Role for CX3CR1+ Macrophages in Tissue Repair

scientific article published on 03 March 2020

Molecular and cellular mechanisms in the viral exacerbation of asthma

scientific article published on July 2008

Mouse Models of Chikungunya Virus

scientific article published on January 2016

Mouse and Cotton Rat Models of Human Respiratory Syncytial Virus

scientific article published on January 2016

Mouse models of alphavirus-induced inflammatory disease.

scientific article

Mutation of a Conserved Nuclear Export Sequence in Chikungunya Virus Capsid Protein Disrupts Host Cell Nuclear Import

scientific article published on 20 October 2017

Mutation of the N-Terminal Region of Chikungunya Virus Capsid Protein: Implications for Vaccine Design

scientific article (publication date: 21 February 2017)

Mutations in nsP1 and PE2 are critical determinants of Ross River virus-induced musculoskeletal inflammatory disease in a mouse model

scientific article

Ocular tropism of SARS-CoV-2 in animal models with retinal inflammation via neuronal invasion following intranasal inoculation

scientific article published in 2022

Osteoblasts from osteoarthritis patients show enhanced susceptibility to Ross River virus infection associated with delayed type I interferon responses

scientific article

Pentosan Polysulfate: a Novel Glycosaminoglycan-Like Molecule for Effective Treatment of Alphavirus-Induced Cartilage Destruction and Inflammatory Disease.

scientific article published on 27 May 2015

Pentraxins and Collectins: Friend or Foe during Pathogen Invasion?

scientific article

Protection from arthritis and myositis in a mouse model of acute chikungunya virus disease by bindarit, an inhibitor of monocyte chemotactic protein-1 synthesis

scientific article published on October 2011

Pulmonary infection of mice with human metapneumovirus induces local cytotoxic T-cell and immunoregulatory cytokine responses similar to those seen with human respiratory syncytial virus

scientific article

RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation

scientific article (publication date: 16 February 2017)

Reverse genetic system, genetically stable reporter viruses and packaged subgenomic replicon based on a Brazilian Zika virus isolate

scientific article published on 12 October 2017

Role of envelope N-linked glycosylation in Ross River virus virulence and transmission

scientific article published on 26 January 2016

Role of human metapneumovirus and respiratory syncytial virus in asthma exacerbations: where are we now?

scientific article published on 30 June 2017

Role of pentraxin 3 in shaping arthritogenic alphaviral disease: from enhanced viral replication to immunomodulation. ⬇️

scientific article

Salivary Transmission of the Chikungunya Arbovirus

scientific article published on 30 December 2015

Small tumor necrosis factor receptor biologics inhibit the tumor necrosis factor-p38 signalling axis and inflammation

scientific article published on 10 April 2018

Specific inhibition of NLRP3 in chikungunya disease reveals a role for inflammasomes in alphavirus-induced inflammation.

scientific article

Sphingosine kinase 1 in viral infections ⬇️

scientific article published on May 28, 2012

Targeting the pro-inflammatory factor CCL2 (MCP-1) with Bindarit for influenza A (H7N9) treatment

scientific article published on 31 March 2017

The genetics of alphaviruses

article

The immunobiology of viral arthritides

scientific article published on 27 September 2009

The medicinal chemistry of dengue fever

scientific article published on December 2009

The molecular and cellular aspects of arthritis due to alphavirus infections: lesson learned from Ross River virus

scientific article published on April 2007

Zika Virus: Mechanisms of Infection During Pregnancy

scientific article

Zika enhancement: a reality check

scientific article published on 21 June 2017

siRNA against the G gene of human metapneumovirus

scientific article

Paulina is supported by:

About Paulina

Help