List of works - Jim-Tong Horng

A CMOS-compatible poly-Si nanowire device with hybrid sensor/memory characteristics for System-on-Chip applications

scientific article

A novel role of ER stress signal transducer ATF6 in regulating enterovirus A71 viral protein stability.

scientific article published on 31 January 2018

Amantadine as a regulator of internal ribosome entry site

scientific article published on 01 November 2008

An extract from Taxodium distichum targets hemagglutinin- and neuraminidase-related activities of influenza virus in vitro

scientific article published on 31 October 2016

Anti-enterovirus 71 activity screening of chinese herbs with anti-infection and inflammation activities.

scientific article published in January 2009

Anti-influenza drug discovery: identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization.

scientific article

Anti-influenza drug discovery: structure-activity relationship and mechanistic insight into novel angelicin derivatives.

scientific article

Antiviral activities of Schizonepeta tenuifolia Briq. against enterovirus 71 in vitro and in vivo

scientific article

Antiviral effects of Salvia miltiorrhiza (Danshen) against enterovirus 71.

scientific article published on January 2007

BPR-3P0128 inhibits RNA-dependent RNA polymerase elongation and VPg uridylylation activities of Enterovirus 71.

scientific article

Characterization of the anti-influenza activity of the Chinese herbal plant Paeonia lactiflora

scientific article

Ching-fang-pai-tu-san inhibits the release of influenza virus

scientific article

Daphne Genkwa Sieb. et Zucc. Water-Soluble Extracts Act on Enterovirus 71 by Inhibiting Viral Entry ⬇️

scientific article published on April 11, 2012

Development of an Anti-Influenza Drug Screening Assay Targeting Nucleoproteins with Tryptophan Fluorescence Quenching ⬇️

scientific article published on July 10, 2012

ER stress, autophagy, and RNA viruses

scientific article

EV71 induces VCAM-1 expression via PDGF receptor, PI3-K/Akt, p38 MAPK, JNK and NF-kappaB in vascular smooth muscle cells

scientific article published on 28 June 2007

Endoplasmic reticulum stress is induced and modulated by enterovirus 71.

scientific article

Enterovirus 71 infection cleaves a negative regulator for viral internal ribosomal entry site-driven translation.

scientific article published on 23 January 2013

Evolutionarily conserved residues at an oligomerization interface of the influenza A virus neuraminidase are essential for viral survival

scientific article published on 14 September 2013

Heterogeneous nuclear ribonuclear protein K interacts with the enterovirus 71 5' untranslated region and participates in virus replication

scientific article

Host MicroRNA miR-197 Plays a Negative Regulatory Role in the Enterovirus 71 Infectious Cycle by Targeting the RAN Protein.

scientific article published on 18 November 2015

Identification of BPR3P0128 as an inhibitor of cap-snatching activities of influenza virus.

scientific article

In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71.

scientific article published on 19 April 2016

Inhibition of endosomal fusion activity of influenza virus by Rheum tanguticum (da-huang)

scientific article published on 15 June 2016

Inhibition of enterovirus 71 entry by transcription factor XBP1.

scientific article

Localization and force analysis at the single virus particle level using atomic force microscopy.

scientific article published on 22 November 2011

Mechanism by which ma-xing-shi-gan-tang inhibits the entry of influenza virus.

scientific article published on 16 June 2012

Mechanism of action of the suppression of influenza virus replication by Ko-Ken Tang through inhibition of the phosphatidylinositol 3-kinase/Akt signaling pathway and viral RNP nuclear export.

scientific article

Parallel screening of wild-type and drug-resistant targets for anti-resistance neuraminidase inhibitors

scientific article

Phosphorylation of PI3K/Akt and MAPK/ERK in an early entry step of enterovirus 71

scientific article published on 08 September 2005

Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity

scientific article

RacGTPase-activating protein 1 interacts with hepatitis C virus polymerase NS5B to regulate viral replication.

scientific article published on 8 October 2014

Reticulon 3 Binds the 2C Protein of Enterovirus 71 and Is Required for Viral Replication

scientific article published in Journal of Biological Chemistry

dsRNA Binding Domain of PKR Is Proteolytically Released by Enterovirus A71 to Facilitate Viral Replication.

scientific article

List of works by Jim-Tong Horng

A CMOS-compatible poly-Si nanowire device with hybrid sensor/memory characteristics for System-on-Chip applications

A novel role of ER stress signal transducer ATF6 in regulating enterovirus A71 viral protein stability.

Amantadine as a regulator of internal ribosome entry site

An extract from Taxodium distichum targets hemagglutinin- and neuraminidase-related activities of influenza virus in vitro

Anti-enterovirus 71 activity screening of chinese herbs with anti-infection and inflammation activities.

Anti-influenza drug discovery: identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization.

Anti-influenza drug discovery: structure-activity relationship and mechanistic insight into novel angelicin derivatives.

Antiviral activities of Schizonepeta tenuifolia Briq. against enterovirus 71 in vitro and in vivo

Antiviral effects of Salvia miltiorrhiza (Danshen) against enterovirus 71.

BPR-3P0128 inhibits RNA-dependent RNA polymerase elongation and VPg uridylylation activities of Enterovirus 71.

Characterization of the anti-influenza activity of the Chinese herbal plant Paeonia lactiflora

Ching-fang-pai-tu-san inhibits the release of influenza virus

Daphne Genkwa Sieb. et Zucc. Water-Soluble Extracts Act on Enterovirus 71 by Inhibiting Viral Entry ⬇️

Development of an Anti-Influenza Drug Screening Assay Targeting Nucleoproteins with Tryptophan Fluorescence Quenching ⬇️

ER stress, autophagy, and RNA viruses

EV71 induces VCAM-1 expression via PDGF receptor, PI3-K/Akt, p38 MAPK, JNK and NF-kappaB in vascular smooth muscle cells

Endoplasmic reticulum stress is induced and modulated by enterovirus 71.

Enterovirus 71 infection cleaves a negative regulator for viral internal ribosomal entry site-driven translation.

Evolutionarily conserved residues at an oligomerization interface of the influenza A virus neuraminidase are essential for viral survival

Heterogeneous nuclear ribonuclear protein K interacts with the enterovirus 71 5' untranslated region and participates in virus replication

Host MicroRNA miR-197 Plays a Negative Regulatory Role in the Enterovirus 71 Infectious Cycle by Targeting the RAN Protein.

Identification of BPR3P0128 as an inhibitor of cap-snatching activities of influenza virus.

In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71.

Inhibition of endosomal fusion activity of influenza virus by Rheum tanguticum (da-huang)

Inhibition of enterovirus 71 entry by transcription factor XBP1.

Localization and force analysis at the single virus particle level using atomic force microscopy.

Mechanism by which ma-xing-shi-gan-tang inhibits the entry of influenza virus.

Mechanism of action of the suppression of influenza virus replication by Ko-Ken Tang through inhibition of the phosphatidylinositol 3-kinase/Akt signaling pathway and viral RNP nuclear export.

Parallel screening of wild-type and drug-resistant targets for anti-resistance neuraminidase inhibitors

Phosphorylation of PI3K/Akt and MAPK/ERK in an early entry step of enterovirus 71

Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity

RacGTPase-activating protein 1 interacts with hepatitis C virus polymerase NS5B to regulate viral replication.

Reticulon 3 Binds the 2C Protein of Enterovirus 71 and Is Required for Viral Replication

dsRNA Binding Domain of PKR Is Proteolytically Released by Enterovirus A71 to Facilitate Viral Replication.