List of works - Daniela Cesana

Comprehensive genomic access to vector integration in clinical gene therapy

scientific article published on 22 November 2009

Cyclosporin a and rapamycin relieve distinct lentiviral restriction blocks in hematopoietic stem and progenitor cells

scientific article published on October 2014

Genotoxicity assay for gene therapy vectors in tumor prone Cdkn2a⁻/⁻ mice.

scientific article published in January 2012

HIV-1-mediated insertional activation of STAT5B and BACH2 trigger viral reservoir in T regulatory cells.

scientific article published on 8 September 2017

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

scientific article (publication date: June 2006)

Lentiviral Vector Promoter is Decisive for Aberrant Transcript Formation

scientific article published on 21 August 2017

Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection

scientific article published on 14 March 2011

Lentiviral vector integration profiles differ in rodent postmitotic tissues

scientific article

Lentiviral vector-based insertional mutagenesis identifies genes associated with liver cancer

scientific article published on 13 January 2013

Phagocytosis-shielded lentiviral vectors improve liver gene therapy in nonhuman primates

scientific article published on 01 May 2019

Reciprocal regulation of Notch and PI3K/Akt signalling in T-ALL cells In Vitro

scientific article published on 01 April 2008

Site-specific integration and tailoring of cassette design for sustainable gene transfer.

scientific article published on 21 August 2011

The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy

scientific article published on 23 March 2009

Uncovering and dissecting the genotoxicity of self-inactivating lentiviral vectors in vivo