List of works by John V. Williams

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

scientific article published on 04 September 2020

741. Impact of Adenovirus Co-detections on Illness Severity

A broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus

scientific article

A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction

scientific article published on 11 February 2009

A critical phenylalanine residue in the respiratory syncytial virus fusion protein cytoplasmic tail mediates assembly of internal viral proteins into viral filaments and particles

scientific article published on 7 February 2012

A household-based study of acute viral respiratory illnesses in Andean children

scientific article

A mechanistic role for type III IFN-λ1 in asthma exacerbations mediated by human rhinoviruses

scientific article

A medium-throughput screen for inhibitors of human metapneumovirus

A novel group of rhinoviruses is associated with asthma hospitalizations

scientific article published on 22 November 2008

A prospective study comparing human metapneumovirus with other respiratory viruses in adults with hematologic malignancies and respiratory tract infections

scientific article

A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo

scientific article

A respiratory syncytial virus attachment (G) gene variant associated with more severe disease in infants decreases fusion (F) protein expression which may facilitate immune evasion

scientific article published on 28 October 2020

Acute Viral Respiratory Infection Rapidly Induces a CD8+ T Cell Exhaustion-like Phenotype

scientific article published on 23 September 2015

Acute clearance of human metapneumovirus occurs independently of natural killer cells

scientific article

Adherence to guidelines for respiratory syncytial virus immunoprophylaxis among infants with prematurity or chronic lung disease in three United States counties

scientific article

An alphavirus replicon-based human metapneumovirus vaccine is immunogenic and protective in mice and cotton rats

scientific article published on 10 September 2008

Animal models for human metapneumovirus (HMPV) infections

scientific article published on 21 December 2006

Antiviral treatment among older adults hospitalized with influenza, 2006-2012

scientific article

Association of human metapneumovirus with acute otitis media

scientific article

B Cell-Intrinsic mTORC1 Promotes Germinal Center-Defining Transcription Factor Gene Expression, Somatic Hypermutation, and Memory B Cell Generation in Humoral Immunity.

scientific article published on 12 March 2018

Burden of human metapneumovirus infection in young children

scientific article published on February 2013

Burden of respiratory syncytial virus in hospitalized infants and young children in Amman, Jordan

scientific article

CD4 Regulatory T Cells Exert Differential Functions during Early and Late Stages of the Immune Response to Respiratory Viruses

scientific article published on 11 July 2018

Clinical effectiveness of split-virion versus subunit trivalent influenza vaccines in older adults

scientific article published on 18 February 2015

Cohort profile: The study of respiratory pathogens in Andean children

scientific article

Comparison of the MChip to viral culture, reverse transcription-PCR, and the QuickVue influenza A+B test for rapid diagnosis of influenza

scientific article

Concordance between RT-PCR-based detection of respiratory viruses from nasal swabs collected for viral testing and nasopharyngeal swabs collected for bacterial testing

scientific article

Coronavirus infection and hospitalizations for acute respiratory illness in young children

scientific article published on May 2009

Density interactions among Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in the nasopharynx of young Peruvian children

scientific article

Design and synthesis of acyclic nucleoside analogs with chlorinated imidazo[1,2-a]pyridine bases.

scientific article published on October 2003

Design, synthesis, and antiviral activity of certain 3-substituted 2,5,6-trichloroindole nucleosides.

scientific article

Design, synthesis, and antiviral evaluation of some polyhalogenated indole C-nucleosides.

scientific article published on January 2005

Detection of influenza by real time RT-PCR is not affected by delays in respiratory specimen processing

scientific article published on 18 April 2016

Detection of viruses in human adenoid tissues by use of multiplex PCR.

scientific article published on 30 December 2008

Development and optimization of a direct plaque assay for trypsin-dependent human metapneumovirus strains

article

Development of a low-resource RNA extraction cassette based on surface tension valves

scientific article

Diagnostic performance of the BinaxNow Influenza A&B rapid antigen test in ED patients

scientific article published on 15 July 2012

Differential pathogenesis of respiratory syncytial virus clinical isolates in BALB/c mice

scientific article

Discovering naturally processed antigenic determinants that confer protective T cell immunity

scientific article published on April 2013

Discovery, characterization and comparison of inhibitors of Bacillus anthracis and Staphylococcus aureus replicative DNA helicases

scientific article

Disparities between black and white children in hospitalizations associated with acute respiratory illness and laboratory-confirmed influenza and respiratory syncytial virus in 3 US counties--2002-2009.

scientific article published on 22 February 2013

Effectiveness of influenza vaccine for preventing laboratory-confirmed influenza hospitalizations in adults, 2011-2012 influenza season

scientific article published on 28 February 2013

Effectiveness of non-adjuvanted pandemic influenza A vaccines for preventing pandemic influenza acute respiratory illness visits in 4 U.S. communities

scientific article (publication date: 2011)

Effectiveness of seasonal influenza vaccines in the United States during a season with circulation of all three vaccine strains

scientific article published on 25 July 2012

Effectiveness of seasonal vaccine in preventing confirmed influenza-associated hospitalizations in community dwelling older adults

scientific article

Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR.

scientific article published on 10 February 2010

Emergency department visits for influenza A(H1N1)pdm09, Davidson County, Tennessee, USA

scientific article

Epidemiology and Clinical Characteristics of Influenza C Virus

scientific article published on 13 January 2020

Estimating age-specific influenza-related hospitalization rates during the pandemic (H1N1) 2009 in Davidson Co, TN.

scientific article

Evaluating the diagnostic accuracy of the WHO Severe Acute Respiratory Infection (SARI) criteria in Middle Eastern children under two years over three respiratory seasons

scientific article published on 30 April 2020

Examination of a fusogenic hexameric core from human metapneumovirus and identification of a potent synthetic peptide inhibitor from the heptad repeat 1 region

scientific article published on 11 October 2006

Failure of routine diagnostic methods to detect influenza in hospitalized older adults

scientific article published on July 2010

Genetic diversity and evolution of human metapneumovirus fusion protein over twenty years

scientific article published on 9 September 2009

Genetic diversity and molecular evolution of the major human metapneumovirus surface glycoproteins over a decade.

scientific article published on 4 September 2013

Genomic analysis of four human metapneumovirus prototypes

scientific article

Hospitalizations and outpatient visits for rhinovirus-associated acute respiratory illness in adults

scientific article published on 6 August 2015

Host and viral factors associated with severity of human rhinovirus-associated infant respiratory tract illness

scientific article

Human Metapneumovirus Infection in Jordanian Children: Epidemiology and Risk Factors for Severe Disease

scientific article published on 12 September 2015

Human Metapneumovirus Is Capable of Entering Cells by Fusion with Endosomal Membranes

scientific article

Human coronavirus NL63 is not detected in the respiratory tracts of children with acute Kawasaki disease

scientific article

Human coronavirus in young children hospitalized for acute respiratory illness and asymptomatic controls

scientific article published on March 2012

Human coronavirus-NL63 infection is not associated with acute Kawasaki disease.

scientific article

Human metapneumovirus - what we know now.

scientific article

Human metapneumovirus G protein is highly conserved within but not between genetic lineages

scientific article published on 6 February 2013

Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children

scientific article published on January 2004

Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats

scientific article published on 18 October 2006

Human metapneumovirus in hospitalized children in Amman, Jordan

scientific article

Human metapneumovirus infection in children hospitalized for wheezing

scientific article published on June 2005

Human metapneumovirus infection plays an etiologic role in acute asthma exacerbations requiring hospitalization in adults

scientific article

Human metapneumovirus nucleoprotein and phosphoprotein interact and provide the minimal requirements for inclusion body formation

scientific article published on November 2008

Human metapneumovirus small hydrophobic (SH) protein downregulates type I IFN pathway signaling by affecting STAT1 expression and phosphorylation

scientific article published on 27 April 2016

Human metapneumovirus virus-like particles induce protective B and T cell responses in a mouse model

scientific article

Human rhinovirus C associated with wheezing in hospitalised children in the Middle East

scientific article published on 05 July 2009

Human rhinovirus C infections in pediatric hematology and oncology patients

scientific article

Human rhinovirus C: Age, season, and lower respiratory illness over the past 3 decades

scientific article

Human rhinovirus species associated with hospitalizations for acute respiratory illness in young US children

scientific article published on 19 October 2011

Identification of Invasive Salmonella Enterica Serovar Typhimurium ST313 in Ambulatory HIV-Infected Adults in Mozambique

scientific article

Immunogenicity and efficacy of alphavirus-derived replicon vaccines for respiratory syncytial virus and human metapneumovirus in nonhuman primates

scientific article published on 6 January 2016

Impact of a school-based influenza immunization program on disease burden: comparison of two Tennessee counties

scientific article published on 24 February 2009

Impact of home environment interventions on the risk of influenza-associated ARI in Andean children: observations from a prospective household-based cohort study

scientific article published on 12 March 2014

Incidence and Risk Factors for Respiratory Syncytial Virus and Human Metapneumovirus Infections among Children in the Remote Highlands of Peru

scientific article published on 24 June 2015

Infant and adult human B cell responses to rotavirus share common immunodominant variable gene repertoires

scientific article published in November 2003

Influence of maternal asthma on the cause and severity of infant acute respiratory tract infections

scientific article published on 14 February 2012

Influenza in older adults: impact of vaccination of school children

scientific article published on 31 January 2009

Influenza vaccine prevents medically attended influenza-associated acute respiratory illness in adults aged ≥50 years

scientific article published on 21 October 2014

Influenza-related hospitalization and ED visits in children less than 5 years: 2000-2011.

scientific article

Integrin alphavbeta1 promotes infection by human metapneumovirus

scholarly article

Lung CD8+ T Cell Impairment Occurs during Human Metapneumovirus Infection despite Virus-Like Particle Induction of Functional CD8+ T Cells

scientific article published on 10 June 2015

Macronutrients during pregnancy and life-threatening respiratory syncytial virus infections in children

scientific article published in May 2013

Medical and economic impact of a respiratory syncytial virus outbreak in a neonatal intensive care unit

scientific article

Middle East respiratory syndrome coronavirus not detected in children hospitalized with acute respiratory illness in Amman, Jordan, March 2010 to September 2012

scientific article

Molecular Epidemiology of Rhinovirus Detections in Young Children

scientific article published on 13 January 2016

Molecular characterization of respiratory syncytial viruses infecting children reported to have received palivizumab immunoprophylaxis

scientific article published on 24 January 2015

Multiple Inhibitory Pathways Contribute to Lung CD8+ T Cell Impairment and Protect against Immunopathology during Acute Viral Respiratory Infection

scientific article published on 3 June 2016

Natural history and epidemiology of respiratory syncytial virus infection in the Middle East: Hospital surveillance for children under age two in Jordan.

scientific article

New Approaches for Immunization and Therapy against Human Metapneumovirus

scientific article published on 10 June 2015

Novel HLA-A2-restricted human metapneumovirus epitopes reduce viral titers in mice and are recognized by human T cells

scientific article published on 19 April 2016

Novel bis-indole agents active against multidrug-resistant Acinetobacter baumannii.

scientific article published on January 2011

Population-based incidence of human metapneumovirus infection among hospitalized children

scientific article

Programmed death-1 impairs secondary effector lung CD8⁺ T cells during respiratory virus reinfection

scientific article published on 22 October 2014

Prospective study of the incidence, clinical features, and outcome of symptomatic upper and lower respiratory tract infections by respiratory viruses in adult recipients of hematopoietic stem cell transplants for hematologic malignancies

scientific article

Rates of hospitalizations for respiratory syncytial virus, human metapneumovirus, and influenza virus in older adults

scientific article

Real-time reverse transcription-PCR assay for comprehensive detection of human rhinoviruses

scientific article published on 5 December 2007

Real-world comparison of two molecular methods for detection of respiratory viruses

scientific article

Reining in the CD8+ T cell: Respiratory virus infection and PD-1-mediated T-cell impairment

scholarly article published by Meredith C Rogers in 2019

Respiratory Viral Detections During Symptomatic and Asymptomatic Periods in Young Andean Children

scientific article

Respiratory syncytial virus- and human metapneumovirus-associated emergency department and hospital burden in adults

scientific article published on 07 February 2014

Respiratory syncytial virus-associated hospitalizations among children less than 24 months of age.

scientific article published on 22 July 2013

Respiratory virus shedding in a cohort of on-duty healthcare workers undergoing prospective surveillance

scientific article published on 08 February 2013

Role of type I interferon signaling in human metapneumovirus pathogenesis and control of viral replication

scientific article published on 4 February 2015

Sequencing and analysis of globally obtained human respiratory syncytial virus A and B genomes

scientific article

Seroepidemiologies of human metapneumovirus and respiratory syncytial virus in young children, determined with a new recombinant fusion protein enzyme-linked immunosorbent assay

scientific article published on 14 August 2013

Seroreactivity to HPV-16 proteins in women with early cervical neoplasia

scientific article published on January 1, 1992

Severe ehrlichia infection in pediatric oncology and stem cell transplant patients

scientific article published on May 2010

Severe outcomes associated with respiratory viruses in newborns and infants: a prospective viral surveillance study in Jordan.

scientific article

Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes

scientific article

Soluble recombinant human metapneumovirus G protein is immunogenic but not protective

scientific article

Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site

scientific article

Studies of culture conditions and environmental stability of human metapneumovirus

scientific article

Synthesis and antiviral activity of novel erythrofuranosyl imidazo[1,2-a]pyridine C-nucleosides constructed via palladium coupling of iodoimidazo[1,2-a]pyridines and dihydrofuran.

scientific article published on April 2003

Synthesis and antiviral activity of some 2-substituted 3-formyl- and 3-cyano-5,6-dichloroindole nucleosides.

scientific article published on January 2005

Synthesis and antiviral evaluation of some novel tricyclic pyrazolo[3,4-b]indole nucleosides.

scientific article published on May 2004

Synthesis, antiviral activity, and mode of action of some 3-substituted 2,5,6-trichloroindole 2'- and 5'-deoxyribonucleosides.

scientific article

Taxonomy of the order Mononegavirales: second update 2018

scientific article published on 01 April 2019

Taxonomy of the order Mononegavirales: update 2019

scientific article published on 01 July 2019

The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity

scientific article

The human metapneumovirus fusion protein mediates entry via an interaction with RGD-binding integrins

scientific article

The human neonatal B cell response to respiratory syncytial virus uses a biased antibody variable gene repertoire that lacks somatic mutations

scientific article published on 4 October 2009

The pediatric burden of human coronaviruses evaluated for twenty years

scientific article published on August 2009

The role of human metapneumovirus in upper respiratory tract infections in children: a 20-year experience

scientific article

The role of influenza and parainfluenza infections in nasopharyngeal pneumococcal acquisition among young children

scientific article published on 12 March 2014

Viral acute lower respiratory infections impair CD8+ T cells through PD-1

scientific article

Viral etiologies of infant bronchiolitis, croup and upper respiratory illness during 4 consecutive years

scientific article published on September 2013

WHO Severe Acute Respiratory Infections (SARI) Definition often Underdiagnoses Serious Respiratory Viral Infections in Hospitalized Jordanian Children.

scientific article published on 4 October 2017