List of works by Jin Chen

A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis.

scientific article published in November 2005

An enhancer element in the EphA2 (Eck) gene sufficient for rhombomere-specific expression is activated by HOXA1 and HOXB1 homeobox proteins.

scientific article

Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium

scientific article

Arginine N-methyltransferase 1 is required for early postimplantation mouse development, but cells deficient in the enzyme are viable

scientific journal article

B Cell-Intrinsic mTORC1 Promotes Germinal Center-Defining Transcription Factor Gene Expression, Somatic Hypermutation, and Memory B Cell Generation in Humoral Immunity.

scientific article published on 12 March 2018

Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis

scientific article

Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

scientific article

CD148 tyrosine phosphatase promotes cadherin cell adhesion

scientific article

Cloning a eukaryotic DNA glycosylase repair gene by the suppression of a DNA repair defect in Escherichia coli

scientific article

Constitutive expression of BCL-X(L) in the T lineage attenuates collagen-induced arthritis in Bcl-X(L) transgenic mice

scientific article published in February 2002

Cooperative signaling between Slit2 and Ephrin-A1 regulates a balance between angiogenesis and angiostasis.

scientific article

Determination of the CD148-Interacting Region in Thrombospondin-1

scientific article

Disruption of the Scaffolding Function of mLST8 Selectively Inhibits mTORC2 Assembly and Function and Suppresses mTORC2-Dependent Tumor Growth In Vivo

scientific article published on 13 May 2019

EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer

scientific article published on 7 January 2016

Effects of cancer-associated EPHA3 mutations on lung cancer.

scientific article published on 24 July 2012

Elevated Slit2 Activity Impairs VEGF-Induced Angiogenesis and Tumor Neovascularization in EphA2-Deficient Endothelium

scientific article

Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy.

scientific article published on 22 December 2009

Eph Receptor Tyrosine Kinases in Tumor Immunity

scientific article published on 3 November 2016

Eph receptor tyrosine kinases in angiogenesis: from development to disease.

scientific article published in January 2004

Eph receptor tyrosine kinases in cancer stem cells

scientific article

Eph receptor tyrosine kinases in tumor and tumor microenvironment

scientific article

Eph receptors and Ephrins in cancer: common themes and controversies.

scientific article published on December 2008

Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.

scientific article published on 22 December 2008

Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome.

scientific article

EphA2 Expression Regulates Inflammation and Fibroproliferative Remodeling in Atherosclerosis.

scientific article published on 9 May 2017

EphA2 activation promotes the endothelial cell inflammatory response: a potential role in atherosclerosis

scientific article published on 12 January 2012

EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics.

scientific article

EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation.

scientific article published on 30 March 2004

EphA2 signaling following endocytosis: role of Tiam1.

scientific article published on 10 October 2013

Ephrin-A1 facilitates mammary tumor metastasis through an angiogenesis-dependent mechanism mediated by EphA receptor and vascular endothelial growth factor in mice

scientific article published on 01 November 2006

Ephrin-B1 transduces signals to activate integrin-mediated migration, attachment and angiogenesis.

scientific article published in August 2002

Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase.

scientific article

Essential role of T cell NF-kappa B activation in collagen-induced arthritis

scientific article published on 01 August 1999

Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis

scientific journal article

Expression of the TAL1/SCL transcription factor in physiological and pathological vascular processes

scientific article published on September 2006

Genetic and pharmacologic inhibition of EPHA2 promotes apoptosis in NSCLC.

scientific article published on 8 April 2014

Germ-line inactivation of the murine Eck receptor tyrosine kinase by gene trap retroviral insertion.

scientific article published in March 1996

Host deficiency in Vav2/3 guanine nucleotide exchange factors impairs tumor growth, survival, and angiogenesis in vivo

scientific article published on 12 May 2009

Identification and functional analysis of phosphorylated tyrosine residues within EphA2 receptor tyrosine kinase.

scientific article published on 3 April 2008

Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression

scientific article published on 15 September 2005

In vivo function of an interleukin 2 receptor beta chain (IL-2Rbeta)/IL-4Ralpha cytokine receptor chimera potentiates allergic airway disease.

scientific article

In vivo hyperspectral imaging of microvessel response to trastuzumab treatment in breast cancer xenografts.

scientific article

Induction of S.cerevisiae MAG 3-methyladenine DNA glycosylase transcript levels in response to DNA damage

scientific article published on December 1991

Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors

scientific article

Inhibition of retinal neovascularization by soluble EphA2 receptor

scientific article published on 15 December 2005

JNK signaling mediates EPHA2-dependent tumor cell proliferation, motility, and cancer stem cell-like properties in non-small cell lung cancer

scientific article published on 7 March 2014

Keratinocyte transglutaminase: regulation and release

scientific article published on 01 January 1988

LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer).

scientific article

Loss of EphA2 receptor tyrosine kinase reduces ApcMin/+ tumorigenesis

scientific article

Microenvironmental Metabolism Regulates Antitumor Immunity

scientific article published on 30 July 2019

Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism.

scientific article published on 15 January 2008

Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function.

scientific article published in November 2006

Phosphorylation of PLCγ1 by EphA2 receptor tyrosine kinase promotes tumor growth in lung cancer

scientific article published on 04 August 2020

Primary sequence and biological functions of a Saccharomyces cerevisiae O6-methylguanine/O4-methylthymine DNA repair methyltransferase gene

scientific article

Production of germ-line chimeras in zebrafish by cell transplants from genetically pigmented to albino embryos

scientific article published on May 1992

Radiation Response and Reliability of High Speed AlGaN/GaN HEMTs ⬇️

doctoral dissertation

Radiation response and reliability of AlGaN/GaN HEMTS ⬇️

master's thesis

Redirection of T cell effector function in vivo and enhanced collagen-induced arthritis mediated by an IL-2R beta/IL-4R alpha chimeric cytokine receptor transgene

scientific article published in March 2001

Regulation of EphA2 receptor endocytosis by SHIP2 lipid phosphatase via phosphatidylinositol 3-Kinase-dependent Rac1 activation

scientific article published on 29 November 2006

Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.

scientific article

Regulation of heart valve morphogenesis by Eph receptor ligand, ephrin-A1

scientific journal article

Regulation of mammary gland branching morphogenesis by EphA2 receptor tyrosine kinase

scientific journal article

Regulation of tumor initiation and metastatic progression by Eph receptor tyrosine kinases.

scientific article published on January 2012

Retrovirus gene traps

scientific article published on 01 January 1995

Reverse endocytosis of transmembrane ephrin-B ligands via a clathrin-mediated pathway.

scientific article

Rictor amplification promotes NSCLC cell proliferation through formation and activation of mTORC2 at the expense of mTORC1

scientific article published on 14 August 2020

Saccharomyces cerevisiae 3-methyladenine DNA glycosylase has homology to the AlkA glycosylase of E. coli and is induced in response to DNA alkylation damage.

scientific article

Selective targeting p53WT lung cancer cells harboring homozygous p53 Arg72 by an inhibitor of CypA.

scientific article published on 10 April 2017

Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo.

scientific article published in October 2002

Targeting EphA2 impairs cell cycle progression and growth of basal-like/triple-negative breast cancers

scientific article published on 05 June 2017

The CCL2 chemokine is a negative regulator of autophagy and necrosis in luminal B breast cancer cells

scientific article published on 6 March 2015

The Ephrin-A1/EPHA2 Signaling Axis Regulates Glutamine Metabolism in HER2-Positive Breast Cancer.

scientific article published on February 2016

The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus

scientific article

The ephrins and Eph receptors in angiogenesis

scientific article (publication date: February 2002)

The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ.

scientific article published on 5 December 2017

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

scientific article

Tie2 receptor tyrosine kinase, a major mediator of tumor necrosis factor alpha-induced angiogenesis in rheumatoid arthritis

scientific article published in September 2003

Tie2 signaling regulates osteoclastogenesis and osteolytic bone invasion of breast cancer

scientific article

Transcriptional specificity of the pluripotent embryonic stem cell.

scientific article published in October 1996

Tumor necrosis factor-alpha induction of endothelial ephrin A1 expression is mediated by a p38 MAPK- and SAPK/JNK-dependent but nuclear factor-kappa B-independent mechanism.

scientific article

VAMP-associated protein B (VAPB) promotes breast tumor growth by modulation of Akt activity

scientific article

Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia

scientific article published on 2 April 2012

mTORC1 and mTORC2 in cancer and the tumor microenvironment

scientific article

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