List of works - Sathyamangalam Swaminathan

A custom-designed recombinant multiepitope protein as a dengue diagnostic reagent

scientific article published on May 2005

A highly sensitive and specific time resolved fluorometric bridge assay for antibodies to HIV-1 and -2.

scientific article published on 11 January 2011

A quinoline compound inhibits the replication of dengue virus serotypes 1-4 in Vero cells

scientific article published on 27 March 2018

A small molecule inhibitor of dengue virus type 2 protease inhibits the replication of all four dengue virus serotypes in cell culture

scientific article

A synthetic dengue virus antigen elicits enhanced antibody titers when linked to, but not mixed with, Mycobacterium tuberculosis HSP70 domain II.

scientific article

A tetravalent virus-like particle vaccine designed to display domain III of dengue envelope proteins induces multi-serotype neutralizing antibodies in mice and macaques which confer protection against antibody dependent enhancement in AG129 mice

scientific article published on 8 January 2018

Abrogation of a mitotic checkpoint by E2 proteins from oncogenic human papillomaviruses correlates with increased turnover of the p53 tumor suppressor protein.

scientific article

Adenovirus delivered short hairpin RNA targeting a conserved site in the 5' non-translated region inhibits all four serotypes of dengue viruses

scientific article

Adenovirus-vectored vaccines

scientific article published on March 2008

Affinity purification of recombinant interferon-alpha on a mimetic ligand adsorbent

scientific article published on 01 March 1999

An adenovirus prime/plasmid boost strategy for induction of equipotent immune responses to two dengue virus serotypes

scientific article (publication date: 15 February 2007)

An adenovirus type 5 (AdV5) vector encoding an envelope domain III-based tetravalent antigen elicits immune responses against all four dengue viruses in the presence of prior AdV5 immunity

scientific article published on 7 August 2009

An envelope domain III-based chimeric antigen produced in Pichia pastoris elicits neutralizing antibodies against all four dengue virus serotypes.

scientific article published on September 2008

Application of simple fed-batch technique to high-level secretory production of insulin precursor using Pichia pastoris with subsequent purification and conversion to human insulin

scientific article published on 12 May 2010

Chimeric Hepatitis B core antigen virus-like particles displaying the envelope domain III of dengue virus type 2.

scientific article published on 13 July 2012

Cissampelos pareira Linn: Natural Source of Potent Antiviral Activity against All Four Dengue Virus Serotypes

scientific article (publication date: December 2015)

Dengue envelope-based 'four-in-one' virus-like particles produced using Pichia pastoris induce enhancement-lacking, domain III-directed tetravalent neutralising antibodies in mice.

scientific article published on 5 June 2018

Dengue vaccine development: Global and Indian scenarios

scientific article published on 23 January 2019

Dengue vaccine efficacy trial: does interference cause failure?

scientific article published on March 2013

Dengue vaccines: state of the art.

scientific article

Dengue-specific subviral nanoparticles: design, creation and characterization

scientific article published on 25 May 2013

Dengue: recent advances in biology and current status of translational research

scientific article published on March 2009

Diagnostic potential and antigenic properties of recombinant tick-borne encephalitis virus subviral particles expressed in mammalian cells from Semliki Forest virus replicons

scientific article

Drugs for dengue: a patent review (2010-2014).

scientific article published on 06 October 2014

Effect of copy number on the expression levels of hepatitis B surface antigen in the methylotrophic yeast Pichia pastoris

scientific article published on 01 February 2001

Electrospun manganese (III) oxide nanofiber based electrochemical DNA-nanobiosensor for zeptomolar detection of dengue consensus primer.

scientific article

Escherichia coli-expressed near full length HIV-1 envelope glycoprotein is a highly sensitive and specific diagnostic antigen

scientific article

Evaluation of envelope domain III-based single chimeric tetravalent antigen and monovalent antigen mixtures for the detection of anti-dengue antibodies in human sera

scientific article

Expression of hepatitis B surface antigen in the methylotrophic yeast Pichia pastoris using the GAP promoter.

scientific article published in June 2001

Expression, purification and characterization of in vivo biotinylated dengue virus envelope domain III based tetravalent antigen.

scientific article published on 7 May 2010

High-level expression and one-step purification of recombinant dengue virus type 2 envelope domain III protein in Escherichia coli

scientific article published on January 2004

Induction of neutralizing antibodies and T cell responses by dengue virus type 2 envelope domain III encoded by plasmid and adenoviral vectors.

scientific article

Induction of neutralizing antibodies specific to dengue virus serotypes 2 and 4 by a bivalent antigen composed of linked envelope domains III of these two serotypes

scientific article

Inexpensive designer antigen for anti-HIV antibody detection with high sensitivity and specificity.

scientific article published on 20 January 2010

Investigational drugs in early development for treating dengue infection.

scientific article published on 20 June 2016

Major antifungal activity from the bulbs of Indian squill Urginea indica is a chitinase

scientific article published on May 2006

Next generation designer virus-like particle vaccines for dengue

scientific article published on 17 January 2019

Optimization of conditions for secretion of dengue virus type 2 envelope domain III using Pichia pastoris

scientific article published on 2 June 2010

Pichia pastoris-Expressed Bivalent Virus-Like Particulate Vaccine Induces Domain III-Focused Bivalent Neutralizing Antibodies without Antibody-Dependent Enhancement in Vivo

scientific article published in January 2017

Pichia pastoris-expressed Zika virus envelope domain III on a virus-like particle platform: design, production and immunological evaluation

scientific article published on 01 April 2019

Pichia pastoris-expressed dengue 2 envelope forms virus-like particles without pre-membrane protein and induces high titer neutralizing antibodies

scientific article

Pichia pastoris-expressed dengue 3 envelope-based virus-like particles elicit predominantly domain III-focused high titer neutralizing antibodies.

scientific article published on 23 September 2015

Pichia pastoris-expressed dengue virus type 2 envelope domain III elicits virus-neutralizing antibodies.

scientific article published on 6 March 2010

Recombinant Dengue Virus 4 Envelope Glycoprotein Virus-Like Particles Derived from Pichia pastoris are Capable of Eliciting Homotypic Domain III-Directed Neutralizing Antibodies.

scientific article

Recombinant dengue virus type 2 envelope/hepatitis B surface antigen hybrid protein expressed in Pichia pastoris can function as a bivalent immunogen.

scientific article published on October 2002

Recombinant multiepitope protein for early detection of dengue infections.

scientific article

Replication-Defective Adenoviral Vaccine Vector for the Induction of Immune Responses to Dengue Virus Type 2

scientific article

Simple high-cell density fed-batch technique for high-level recombinant protein production with Pichia pastoris: Application to intracellular production of Hepatitis B surface antigen

scientific article published on 10 February 2009

Simultaneous detection of Human Immunodeficiency Virus 1 and Hepatitis B virus infections using a dual-label time-resolved fluorometric assay.

scientific article published on 26 November 2010

The identification of immunodominant linear epitopes of dengue type 2 virus capsid and NS4a proteins using pin-bound peptides.

scientific article

The prevalence of antibodies to adenovirus serotype 5 in an adult Indian population and implications for adenovirus vector vaccines

scientific article

Virus-like particles derived from Pichia pastoris-expressed dengue virus type 1 glycoprotein elicit homotypic virus-neutralizing envelope domain III-directed antibodies

scientific article

Virus-like particles displaying envelope domain III of dengue virus type 2 induce virus-specific antibody response in mice

scientific article published on 20 December 2012

p300/cAMP-responsive element-binding protein interactions with ets-1 and ets-2 in the transcriptional activation of the human stromelysin promoter

scientific journal article

List of works by Sathyamangalam Swaminathan

A custom-designed recombinant multiepitope protein as a dengue diagnostic reagent

A highly sensitive and specific time resolved fluorometric bridge assay for antibodies to HIV-1 and -2.

A quinoline compound inhibits the replication of dengue virus serotypes 1-4 in Vero cells

A small molecule inhibitor of dengue virus type 2 protease inhibits the replication of all four dengue virus serotypes in cell culture

A synthetic dengue virus antigen elicits enhanced antibody titers when linked to, but not mixed with, Mycobacterium tuberculosis HSP70 domain II.

A tetravalent virus-like particle vaccine designed to display domain III of dengue envelope proteins induces multi-serotype neutralizing antibodies in mice and macaques which confer protection against antibody dependent enhancement in AG129 mice

Abrogation of a mitotic checkpoint by E2 proteins from oncogenic human papillomaviruses correlates with increased turnover of the p53 tumor suppressor protein.

Adenovirus delivered short hairpin RNA targeting a conserved site in the 5' non-translated region inhibits all four serotypes of dengue viruses

Adenovirus-vectored vaccines

Affinity purification of recombinant interferon-alpha on a mimetic ligand adsorbent

An adenovirus prime/plasmid boost strategy for induction of equipotent immune responses to two dengue virus serotypes

An adenovirus type 5 (AdV5) vector encoding an envelope domain III-based tetravalent antigen elicits immune responses against all four dengue viruses in the presence of prior AdV5 immunity

An envelope domain III-based chimeric antigen produced in Pichia pastoris elicits neutralizing antibodies against all four dengue virus serotypes.

Application of simple fed-batch technique to high-level secretory production of insulin precursor using Pichia pastoris with subsequent purification and conversion to human insulin

Chimeric Hepatitis B core antigen virus-like particles displaying the envelope domain III of dengue virus type 2.

Cissampelos pareira Linn: Natural Source of Potent Antiviral Activity against All Four Dengue Virus Serotypes

Dengue envelope-based 'four-in-one' virus-like particles produced using Pichia pastoris induce enhancement-lacking, domain III-directed tetravalent neutralising antibodies in mice.

Dengue vaccine development: Global and Indian scenarios

Dengue vaccine efficacy trial: does interference cause failure?

Dengue vaccines: state of the art.

Dengue-specific subviral nanoparticles: design, creation and characterization

Dengue: recent advances in biology and current status of translational research

Diagnostic potential and antigenic properties of recombinant tick-borne encephalitis virus subviral particles expressed in mammalian cells from Semliki Forest virus replicons

Drugs for dengue: a patent review (2010-2014).

Effect of copy number on the expression levels of hepatitis B surface antigen in the methylotrophic yeast Pichia pastoris

Electrospun manganese (III) oxide nanofiber based electrochemical DNA-nanobiosensor for zeptomolar detection of dengue consensus primer.

Escherichia coli-expressed near full length HIV-1 envelope glycoprotein is a highly sensitive and specific diagnostic antigen

Evaluation of envelope domain III-based single chimeric tetravalent antigen and monovalent antigen mixtures for the detection of anti-dengue antibodies in human sera

Expression of hepatitis B surface antigen in the methylotrophic yeast Pichia pastoris using the GAP promoter.

Expression, purification and characterization of in vivo biotinylated dengue virus envelope domain III based tetravalent antigen.

High-level expression and one-step purification of recombinant dengue virus type 2 envelope domain III protein in Escherichia coli

Induction of neutralizing antibodies and T cell responses by dengue virus type 2 envelope domain III encoded by plasmid and adenoviral vectors.

Induction of neutralizing antibodies specific to dengue virus serotypes 2 and 4 by a bivalent antigen composed of linked envelope domains III of these two serotypes

Inexpensive designer antigen for anti-HIV antibody detection with high sensitivity and specificity.

Investigational drugs in early development for treating dengue infection.

Major antifungal activity from the bulbs of Indian squill Urginea indica is a chitinase

Next generation designer virus-like particle vaccines for dengue

Optimization of conditions for secretion of dengue virus type 2 envelope domain III using Pichia pastoris

Pichia pastoris-Expressed Bivalent Virus-Like Particulate Vaccine Induces Domain III-Focused Bivalent Neutralizing Antibodies without Antibody-Dependent Enhancement in Vivo

Pichia pastoris-expressed Zika virus envelope domain III on a virus-like particle platform: design, production and immunological evaluation

Pichia pastoris-expressed dengue 2 envelope forms virus-like particles without pre-membrane protein and induces high titer neutralizing antibodies

Pichia pastoris-expressed dengue 3 envelope-based virus-like particles elicit predominantly domain III-focused high titer neutralizing antibodies.

Pichia pastoris-expressed dengue virus type 2 envelope domain III elicits virus-neutralizing antibodies.

Recombinant Dengue Virus 4 Envelope Glycoprotein Virus-Like Particles Derived from Pichia pastoris are Capable of Eliciting Homotypic Domain III-Directed Neutralizing Antibodies.

Recombinant dengue virus type 2 envelope/hepatitis B surface antigen hybrid protein expressed in Pichia pastoris can function as a bivalent immunogen.

Recombinant multiepitope protein for early detection of dengue infections.

Replication-Defective Adenoviral Vaccine Vector for the Induction of Immune Responses to Dengue Virus Type 2

Simple high-cell density fed-batch technique for high-level recombinant protein production with Pichia pastoris: Application to intracellular production of Hepatitis B surface antigen

Simultaneous detection of Human Immunodeficiency Virus 1 and Hepatitis B virus infections using a dual-label time-resolved fluorometric assay.

The identification of immunodominant linear epitopes of dengue type 2 virus capsid and NS4a proteins using pin-bound peptides.

The prevalence of antibodies to adenovirus serotype 5 in an adult Indian population and implications for adenovirus vector vaccines

Virus-like particles derived from Pichia pastoris-expressed dengue virus type 1 glycoprotein elicit homotypic virus-neutralizing envelope domain III-directed antibodies

Virus-like particles displaying envelope domain III of dengue virus type 2 induce virus-specific antibody response in mice

p300/cAMP-responsive element-binding protein interactions with ets-1 and ets-2 in the transcriptional activation of the human stromelysin promoter