List of works - Claudia Fallini

A Drosophila model of ALS reveals a partial loss of function of causative human PFN1 mutants.

scientific article published on 3 April 2017

ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation

scientific article

Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination

scientific article

Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons.

scientific article published on March 2016

Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS.

scientific article published on 22 October 2014

Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis

scientific article published on 23 August 2019

Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis

scientific article

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis

scientific article

NEK1 variants confer susceptibility to amyotrophic lateral sclerosis

scientific article

Post-transcriptional regulation of neuro-oncological ventral antigen 1 by the neuronal RNA-binding proteins ELAV

scientific article published on 24 January 2008

Spinal muscular atrophy: the role of SMN in axonal mRNA regulation.

scientific article

TDP-43 and NOVA-1 RNA-binding proteins as competitive splicing regulators of the schizophrenia-associated TNIK gene

scientific article published on 02 August 2019

TDP-43 is recruited to stress granules in conditions of oxidative insult.

scientific article

The 3' untranslated region of human Cyclin-Dependent Kinase 5 Regulatory subunit 1 contains regulatory elements affecting transcript stability

scientific article

The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.

scientific article

The RNA-binding protein FUS/TLS undergoes calcium-mediated nuclear egress during excitotoxic stress and is required for GRIA2 mRNA processing

scientific article published on 15 May 2019

The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP Assembly

scientific article

The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons.

scientific article

Traffic jam at the nuclear pore: All roads lead to nucleocytoplasmic transport defects in ALS/FTD

scientific article published on 14 March 2020

List of works by Claudia Fallini

A Drosophila model of ALS reveals a partial loss of function of causative human PFN1 mutants.

ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation

Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination

Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons.

Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS.

Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis

Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis

NEK1 variants confer susceptibility to amyotrophic lateral sclerosis

Post-transcriptional regulation of neuro-oncological ventral antigen 1 by the neuronal RNA-binding proteins ELAV

Spinal muscular atrophy: the role of SMN in axonal mRNA regulation.

TDP-43 and NOVA-1 RNA-binding proteins as competitive splicing regulators of the schizophrenia-associated TNIK gene

TDP-43 is recruited to stress granules in conditions of oxidative insult.

The 3' untranslated region of human Cyclin-Dependent Kinase 5 Regulatory subunit 1 contains regulatory elements affecting transcript stability

The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.

The RNA-binding protein FUS/TLS undergoes calcium-mediated nuclear egress during excitotoxic stress and is required for GRIA2 mRNA processing

The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP Assembly

The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons.

Traffic jam at the nuclear pore: All roads lead to nucleocytoplasmic transport defects in ALS/FTD