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List of works by Stephen Eyre

14.5 Rheumatoid Arthritis susceptibility loci; STAT4, TRAF1/C5 and 6q23 region, are also associated with Juvenile Idiopathic Arthritis.

scientific article published on 15 September 2008

A functional haplotype of the PADI4 gene associated with rheumatoid arthritis in a Japanese population is not associated in a United Kingdom population

scientific article

A genetic marker at the OLIG3/TNFAIP3 locus associates with methotrexate continuation in early inflammatory polyarthritis: results from the Norfolk Arthritis Register

scientific article published on 5 October 2010

A re-evaluation of three putative functional single nucleotide polymorphisms in rheumatoid arthritis

article

A systematic investigation of confirmed autoimmune loci in early-onset psoriasis reveals an association with IL2/IL21

A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk.

scientific article

ASSIMILATOR: a new tool to inform selection of associated genetic variants for functional studies ⬇️

scientific article published on January 1, 2011

Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis

scientific article published on 02 September 2020

Association of a rheumatoid arthritis susceptibility variant at the CCL21 locus with premature mortality in inflammatory polyarthritis patients

scientific article

Association of protein kinase C alpha (PRKCA) gene with multiple sclerosis in a UK population

scientific article published on 20 May 2004

Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis

scientific article published on 14 January 2010

Association of the CCR5 gene with juvenile idiopathic arthritis

scientific article

Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity?

scientific article

Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis

scientific article

Brief Report: IRF4 Newly Identified as a Common Susceptibility Locus for Systemic Sclerosis and Rheumatoid Arthritis in a Cross-Disease Meta-Analysis of Genome-Wide Association Studies.

scientific article

CD4+ and B Lymphocyte Expression Quantitative Traits at Rheumatoid Arthritis Risk Loci in Patients With Untreated Early Arthritis: Implications for Causal Gene Identification.

scientific article published on 28 November 2017

Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23

scientific article (publication date: November 2016)

Case Study on Rheumatoid Arthritis

scholarly article published 2011

Characterisation of the genomic architecture of human chromosome 17q and evaluation of different methods for haplotype block definition

scientific article

Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits

scientific article published in 2021

Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.

scientific article published on 6 September 2010

Confirmation of association of the REL locus with rheumatoid arthritis susceptibility in the UK population

scientific article published on 27 November 2009

Correction: Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity?

scientific article

Correction: Predicting the Risk of Rheumatoid Arthritis and Its Age of Onset through Modelling Genetic Risk Variants with Smoking.

scientific article

Correlation of C-reactive protein haplotypes with serum C-reactive protein level and response to anti-tumor necrosis factor therapy in UK rheumatoid arthritis patients: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study S

scientific article published on 7 October 2012

Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.

scientific article

EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis

scientific article published on 2 March 2012

Enrichment of vitamin D response elements in RA-associated loci supports a role for vitamin D in the pathogenesis of RA ⬇️

scientific article published on 02 May 2013

Erratum: Corrigendum: Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls

scientific article published on 01 August 2015

Evidence for a novel rheumatoid arthritis susceptibility locus on chromosome 6p.

scientific article published on December 2004

Examining the overlap between genome-wide rare variant association signals and linkage peaks in rheumatoid arthritis

scientific article

Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.

scientific article published on 20 March 2014

Genetic analysis of the Trichuris muris-induced model of colitis reveals QTL overlap and a novel gene cluster for establishing colonic inflammation

scientific article published on 26 February 2013

Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients

scientific article published on June 2012

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

scientific article

Genetics of RA susceptibility, what comes next?

scientific article

Genetics of rheumatoid arthritis: GWAS and beyond.

scientific article published on 07 June 2011

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

scientific article

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

scientific article

HLA-DPB1-COL11A2 and three additional xMHC loci are independently associated with RA in a UK cohort

article

Haplotype analysis in simplex families and novel analytic approaches in a case-control cohort reveal no evidence of association of the CTLA-4 gene with rheumatoid arthritis

scientific article published in March 2004

High resolution linkage and association mapping identifies a novel rheumatoid arthritis susceptibility locus homologous to one linked to two rat models of inflammatory arthritis

article

High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.

scientific article published on 14 February 2014

Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway

scientific article

Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes

article

Identification of BACH2 and RAD51B as rheumatoid arthritis susceptibility loci in a meta-analysis of genome-wide data

scientific article

Identification of a locus for a form of spondyloepiphyseal dysplasia on chromosome 15q26.1: exclusion of aggrecan as a candidate gene

scientific article published in September 2002

Identification of a locus for a form of spondyloepiphyseal dysplasia on chromosome 15q26.1: exclusion of aggrecan as a candidate gene.

scientific article published in June 2005

Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis. ⬇️

scientific article

Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans

scientific article

Immunochip Analyses of Epistasis in Rheumatoid Arthritis Confirm Multiple Interactions within MHC and Suggest Novel Non-MHC Epistatic Signals

scientific article published on 15 February 2016

Investigating CD11c expression as a potential genomic biomarker of response to TNF inhibitor biologics in whole blood rheumatoid arthritis samples

scientific article

Investigation of an interleukin-6 receptor gene polymorphism (rs2228145) as a predictor of cardiovascular mortality in inflammatory polyarthritis: results from the Norfolk Arthritis Register

scientific article

Investigation of association between the TRAF family genes and RA susceptibility

scientific article

Investigation of genetic variation across the protein tyrosine phosphatase gene in patients with rheumatoid arthritis in the UK.

scientific article

Investigation of polymorphisms in the PADI4 gene in determining severity of inflammatory polyarthritis

scientific article published on 24 February 2005

Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap

scientific article

Investigation of susceptibility loci identified in the UK rheumatoid arthritis whole-genome scan in a further series of 217 UK affected sibling pairs

scientific article published on March 2004

Investigation of the MHC2TA gene, associated with rheumatoid arthritis in a Swedish population, in a UK rheumatoid arthritis cohort

scientific article published on November 2006

Investigation of theSLC22A4 gene (associated with rheumatoid arthritis in a Japanese population) in a United Kingdom population of rheumatoid arthritis patients

article

Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis.

scientific article

Major histocompatibility complex harbors widespread genotypic variability of non-additive risk of rheumatoid arthritis including epistasis

scientific article published on 25 April 2016

No Association between Polymorphisms in the Interleukin-15 Gene and Early-Onset Psoriasis in a UK Cohort Suggests Heterogeneity for this Susceptibility Locus Identified in Chinese Psoriasis Patients

article

No evidence for association of the KLF12 gene with rheumatoid arthritis in a large UK cohort

article

Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study

scientific article

One SNP at a Time: Moving beyond GWAS in Psoriasis

scientific article published on 22 January 2016

Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms.

scientific article published on 25 October 2008

Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease

scientific article

Polymorphisms in the IL-12beta and IL-23R genes are associated with psoriasis of early onset in a UK cohort.

scientific article

Polymorphisms in the PTPN22 region are associated with psoriasis of early onset.

scientific article published on 13 March 2008

Polymorphisms in the tumour necrosis factor gene are not associated with severity of inflammatory polyarthritis

scientific article published on March 2004

Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking

scientific article

Rare variants and autoimmune disease

scientific article published on 09 May 2014

Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis

scientific article published on 18 September 2010

Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis

scientific article published on 20 December 2012

Replication of Associations of Genetic Loci Outside the HLA Region With Susceptibility to Anti-Cyclic Citrullinated Peptide-Negative Rheumatoid Arthritis

scientific article published on 19 February 2016

Replication of the association of the COG6 gene with juvenile idiopathic arthritis (JIA).

scientific article

Take Your PICS: Moving from GWAS to Immune Function

scholarly article by Stephen Eyre & Jane Worthington published December 2014 in Immunity

The bacterial skin microbiome in psoriatic arthritis, an unexplored link in pathogenesis: challenges and opportunities offered by recent technological advances

scientific article

The plant cell cycle in context

article

The potential use of expression profiling: implications for predicting treatment response in rheumatoid arthritis

scientific article published on 13 March 2013

The predictive value of serum S100A9 and response to etanercept is not confirmed in a large UK rheumatoid arthritis cohort ⬇️

scientific article

The type 1 diabetes susceptibility gene SUMO4 at IDDM5 is not associated with susceptibility to rheumatoid arthritis or juvenile idiopathic arthritis

article

Two novel polymorphisms in the human transforming growth factor beta 2 gene

article

Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom

article

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases

scientific article

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