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List of works by Travis Lear

A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance

scientific article published on 25 January 2021

A high throughput screen for TMPRSS2 expression identifies FDA-approved and clinically advanced compounds that can limit SARS-CoV-2 entry

scientific article published on 14 August 2020

Crystal structure and interaction studies of the human FBxo3 ApaG domain

scientific article

E3 ligase subunit Fbxo15 and PINK1 kinase regulate cardiolipin synthase 1 stability and mitochondrial function in pneumonia

scientific article

F-box protein Fbxl18 mediates polyubiquitylation and proteasomal degradation of the pro-apoptotic SCF subunit Fbxl7

scientific article

KIAA0317 regulates pulmonary inflammation through SOCS2 degradation

scientific article published on 03 October 2019

Kelch-like protein 42 is a profibrotic ubiquitin E3 ligase involved in systemic sclerosis

scientific article published on 17 February 2020

Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 Ligase

scientific article published on 2 June 2015

Novel PDE4 inhibitors derived from Chinese medicine forsythia

scientific article published on 30 December 2014

Post-translational modification of the interferon gamma receptor alters its stability and signaling.

scientific article published on 7 September 2017

RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity

scientific article

RING finger protein 113A regulates C-X-C chemokine receptor type 4 stability and signaling

scientific article published on 4 October 2017

Receptor for advanced glycation end products is targeted by FBXO10 for ubiquitination and degradation.

scientific article published on 17 May 2017

The Human IL-22 Receptor Is Regulated through the Action of the Novel E3 Ligase Subunit FBXW12, Which Functions as an Epithelial Growth Suppressor.

scientific article published on 11 June 2015

The Proapoptotic F-box Protein Fbxl7 Regulates Mitochondrial Function by Mediating the Ubiquitylation and Proteasomal Degradation of Survivin

scientific article published on 16 March 2015

The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing

scientific article published on 04 October 2019

The proinflammatory role of HECTD2 in innate immunity and experimental lung injury

scientific article

Therapeutic targets in fibrotic pathways

scientific article published on 19 September 2016

Toll-like Receptor 8 Stability Is Regulated by Ring Finger 216 in Response to Circulating MicroRNAs

scientific article published on 01 February 2020

Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4

scientific article

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