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List of works by Steven M Varga

Aged mice exhibit a severely diminished CD8 T cell response following respiratory syncytial virus infection.

scientific article published on 18 September 2013

Altered Treg and cytokine responses in RSV-infected infants.

scientific article

CD11a and CD49d enhance the detection of antigen-specific T cells following human vaccination

scientific article published on 26 June 2017

CD8 T cells inhibit respiratory syncytial virus (RSV) vaccine-enhanced disease.

scientific article published in October 2007

Cellular bioenergetics, caspase activity and glutathione in murine lungs infected with influenza A virus.

scientific article published on 29 August 2013

Comparison of histochemical methods for murine eosinophil detection in an RSV vaccine-enhanced inflammation model.

scientific article published on 29 January 2009

Depletion of alveolar macrophages ameliorates virus-induced disease following a pulmonary coronavirus infection

scientific article

Determining the breadth of the respiratory syncytial virus-specific T cell response

scientific article

Differential role of gamma interferon in inhibiting pulmonary eosinophilia and exacerbating systemic disease in fusion protein-immunized mice undergoing challenge infection with respiratory syncytial virus

scientific article

Editorial: CD8 T cells cut back on calcium intake in the lungs.

scientific article published on June 2010

Effects of aging on the adaptive immune response to respiratory virus infections.

scientific article

Effects of formalin-inactivated respiratory syncytial virus (FI-RSV) in the perinatal lamb model of RSV.

scientific article

Evaluation of the Adaptive Immune Response to Respiratory Syncytial Virus.

scientific article published on January 2016

Fas ligand is required for the development of respiratory syncytial virus vaccine-enhanced disease

scientific article

Fixing a failed vaccine

scientific article published on 01 January 2009

Foxp3+ CD4 regulatory T cells limit pulmonary immunopathology by modulating the CD8 T cell response during respiratory syncytial virus infection

scientific article

Frontline Science: CD40 signaling restricts RNA virus replication in Mϕs, leading to rapid innate immune control of acute virus infection

scientific article published on 22 May 2020

Function and Modulation of Type I Interferons during Respiratory Syncytial Virus Infection

scientific article published on 10 April 2020

Host genetics play a critical role in controlling CD8 T cell function and lethal immunopathology during chronic viral infection.

scientific article

Human respiratory syncytial virus A2 strain replicates and induces innate immune responses by respiratory epithelia of neonatal lambs.

scientific article published on August 2009

IL-13 is required for eosinophil entry into the lung during respiratory syncytial virus vaccine-enhanced disease.

scientific article published in February 2008

Identification of Novel Respiratory Syncytial Virus CD4+ and CD8+ T Cell Epitopes in C57BL/6 Mice

scientific article published on 14 January 2019

Immunopathology in RSV infection is mediated by a discrete oligoclonal subset of antigen-specific CD4(+) T cells.

scientific article

In vivo generation of pathogen-specific Th1 cells in the absence of the IFN-gamma receptor.

scientific article published in September 2005

Independent regulation of lymphocytic choriomeningitis virus-specific T cell memory pools: relative stability of CD4 memory under conditions of CD8 memory T cell loss.

scientific article published on February 2001

Inflammatory IL-15 is required for optimal memory T cell responses

scientific article

Limitations of Foxp3(+) Treg depletion following viral infection in DEREG mice

scientific article

Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection.

scientific article published on 2 January 2018

Modulation of the host immune response by respiratory syncytial virus proteins

scientific article published on 28 February 2017

Mucosal vaccines against respiratory syncytial virus

scientific article

Multiple CD4+ T cell subsets produce immunomodulatory IL-10 during respiratory syncytial virus infection

scientific article published on 15 August 2011

NOX2 protects against prolonged inflammation, lung injury, and mortality following systemic insults.

scientific article published on 27 April 2013

Nanoparticle vaccines against respiratory syncytial virus

scientific article published on 30 November 2020

Overcoming T cell-mediated immunopathology to achieve safe RSV vaccination.

scientific article published on January 2008

Pre-existing neutralizing antibodies prevent CD8 T cell-mediated immunopathology following respiratory syncytial virus infection

scientific article published on 16 December 2019

Proliferative expansion and acquisition of effector activity by memory CD4+ T cells in the lungs following pulmonary virus infection

scientific article

Protective and pathologic roles of the immune response to mouse hepatitis virus type 1: implications for severe acute respiratory syndrome.

scientific article published on July 2009

Pulmonary immunity and immunopathology: lessons from respiratory syncytial virus.

scientific article published on October 2008

Quantifying antigen-specific CD4 T cells during a viral infection: CD4 T cell responses are larger than we think

scientific article published on 31 October 2011

RSV vaccine-enhanced disease is orchestrated by the combined actions of distinct CD4 T cell subsets

scientific article

RSV-induced immunopathology: dynamic interplay between the virus and host immune response

scientific article

Respiratory syncytial virus decreases p53 protein to prolong survival of airway epithelial cells.

scientific article

Respiratory syncytial virus increases lung cellular bioenergetics in neonatal C57BL/6 mice.

scientific article published on 21 March 2014

Respiratory syncytial virus limits alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha) phosphorylation to maintain translation and viral replication

scientific article

Respiratory syncytial virus nonstructural protein 2 specifically inhibits type I interferon signal transduction.

scientific article

Respiratory syncytial virus synergizes with Th2 cytokines to induce optimal levels of TARC/CCL17.

scientific article

Sensitive detection and quantitation of mouse eosinophils in tissues using an enzymatic eosinophil peroxidase assay: its use to rapidly measure pulmonary eosinophilia during experimental respiratory syncytial virus infection of mice

scientific article

Sirolimus alters lung pathology and viral load following influenza A virus infection

scientific article published on 11 July 2017

T cell epitope specificity and pathogenesis of mouse hepatitis virus-1-induced disease in susceptible and resistant hosts.

scientific article

The CD4 T cell response to respiratory syncytial virus infection

scientific article published on August 2014

The CD45RB-associated epitope defined by monoclonal antibody CZ-1 is an activation and memory marker for mouse CD4 T cells.

scientific article published in January 1996

The attachment (G) glycoprotein of respiratory syncytial virus contains a single immunodominant epitope that elicits both Th1 and Th2 CD4+ T cell responses.

scientific article

The number of respiratory syncytial virus (RSV)-specific memory CD8 T cells in the lung is critical for their ability to inhibit RSV vaccine-enhanced pulmonary eosinophilia.

scientific article

The pulmonary localization of virus-specific T lymphocytes is governed by the tissue tropism of infection

scientific article

The relationship between respiratory syncytial virus and asthma

scientific article published on 10 February 2014

The transcription factor Runx3 guards cytotoxic CD8+ effector T cells against deviation towards follicular helper T cell lineage.

scientific article published on 12 June 2017

Understanding respiratory syncytial virus (RSV) vaccine-enhanced disease.

scientific article published on January 2007

Vaccination with a Single-Cycle Respiratory Syncytial Virus Is Immunogenic and Protective in Mice

scientific article published on 19 April 2019

Vbeta14(+) T cells mediate the vaccine-enhanced disease induced by immunization with respiratory syncytial virus (RSV) G glycoprotein but not with formalin-inactivated RSV

scientific article

Viral manipulation of the host immune response.

scientific article published on 10 July 2015

αβ and γδ T‐cell networks and their roles in natural resistance to viral infections ⬇️

scientific article published on October 1, 1997

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