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List of works by William L. Irving

'Favourable' IL28B polymorphisms are associated with a marked increase in baseline viral load in hepatitis C virus subtype 3a infection and do not predict a sustained virological response after 24 weeks of therapy

scientific article published on 13 March 2013

A Diverse Panel of Hepatitis C Virus Glycoproteins for Use in Vaccine Research Reveals Extremes of Monoclonal Antibody Neutralization Resistance.

scientific article published on 23 December 2015

A comprehensive study of the association between hepatitis C virus and glomerulopathy

scientific article published in February 2002

ANTI-CARDIOLIPIN ANTIBODIES IN VIRAL INFECTION

scientific article published in The Lancet

ANTIBODY TO BOTH HUMAN HERPESVIRUS 6 AND CYTOMEGALOVIRUS

scientific article published in The Lancet

Acute hepatitis C virus infection

scientific article published on 22 May 2008

Acute hepatitis C virus infection: a dynamic-and challenging-concept.

scientific article published on 10 November 2010

Acute hepatitis C virus infection: a neglected disease?

scientific article (publication date: August 2006)

Antimicrobial agents

Antiviral treatment discontinuation among hepatitis C-infected individuals with thrombocytopenia.

scientific article published in May 2015

Apolipoprotein E-epsilon 4 protects against severe liver disease caused by hepatitis C virus

scientific article published in August 2002

Association between MHC Class II Alleles and Clearance of Circulating Hepatitis C Virus

scientific article published in 1998

Association between genes of the major histocompatibility complex class II and the outcome of hepatitis C virus infection

scientific article published in May 1999

Association of antibodies to hepatitis C virus glycoproteins 1 and 2 (anti-E1E2) with HCV disease.

scientific article published on 22 January 2008

Best practice in primary care pathology: review 7.

scientific article

CCR5-Δ32 genotype does not improve predictive value of IL28B polymorphisms for treatment response in chronic HCV infection.

scientific article published on 18 April 2013

Chronic hepatitis in children after liver transplantation: role of hepatitis C virus and hepatitis G virus infections.

scientific article published on May 1998

Clinical Care Pathways for Patients With Hepatitis C: Reducing Critical Barriers to Effective Treatment

scientific article published on 6 January 2016

Clinical pathways for patients with newly diagnosed hepatitis C - what actually happens.

scientific article published in April 2006

Clinical relapses and disease activity on magnetic resonance imaging associated with viral upper respiratory tract infections in multiple sclerosis

scientific article

Cohort Profile: The Hepatitis C Virus (HCV) Research UK Clinical Database and Biobank

scientific article published on 27 February 2017

Comorbidities and medications of patients with chronic hepatitis C under specialist care in the UK.

scientific article published on 8 May 2017

Congenital cytomegalovirus infection

Congenital cytomegalovirus infection

Cost-effectiveness of pegylated interferon and ribavirin for patients with chronic hepatitis C treated in routine clinical practice.

scientific article published on 31 March 2009

Cost-effectiveness of the HepCATT intervention in specialist drug clinics to improve case-finding and engagement with HCV treatment for people who inject drugs in England

scientific article published on 26 January 2020

Cross-genotype characterization of genetic diversity and molecular adaptation in hepatitis C virus envelope glycoprotein genes

scientific article published in February 2007

Current knowledge and future perspectives on acute hepatitis C infection.

scientific article published on 16 April 2015

Defective rheumatoid lymphocyte function assessed by Epstein-Barr virus infection in vitro.

scientific article published in December 1982

Dendritic cells cultured from mononuclear cells and CD34 cells in myeloma do not harbour human herpesvirus 8

scientific article published on 01 March 1998

Detection of cytomegalovirus using PCR in serum from renal transplant recipients.

scientific article published on June 1995

Determination of the human antibody response to the epitope defined by the hepatitis C virus-neutralizing monoclonal antibody AP33.

scientific article

Development and clinical validation of the Genedrive point-of-care test for qualitative detection of hepatitis C virus

article

Development of a high-throughput pyrosequencing assay for monitoring temporal evolution and resistance associated variant emergence in the Hepatitis C virus protease coding-region.

scientific article published on 22 July 2014

Development of a strand-specific RT-PCR based assay to detect the replicative form of hepatitis C virus RNA.

scientific article published in May 2001

Diagnosis of acute hepatitis C virus infection and estimated incidence in low- and high-risk English populations.

scientific article published on 10 July 2008

Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes

scientific article published on 28 January 2016

Dual infection with human herpesvirus type 6 and parvovirus B19 in a renal transplant recipient.

scientific article published on June 1994

ENTRADERMAL HEPATITIS B VACCINE

scientific article published in The Lancet

Enhanced Liver Fibrosis (ELF) test accurately identifies liver fibrosis in patients with chronic hepatitis C.

scientific article published in January 2011

Enhanced nanoparticle uptake into virus infected cells: Could nanoparticles be useful in antiviral therapy?

scientific article published on 13 June 2018

Equilibrative nucleoside transporter 1 expression in primary human hepatocytes is highly variable and determines uptake of ribavirin.

scientific article

Establishing the cascade of care for hepatitis C in England-benchmarking to monitor impact of direct acting antivirals.

scientific article published on 14 December 2017

Estimated progression rates in three United Kingdom hepatitis C cohorts differed according to method of recruitment.

scientific article

Evaluation of area-based collagen scoring by nonlinear microscopy in chronic hepatitis C-induced liver fibrosis

scientific article published on 11 March 2015

Evolutionary dynamics of hepatitis C virus envelope genes during chronic infection.

scientific article published in July 2005

Evolutionary trends of the first hypervariable region of the hepatitis C virus E2 protein in individuals with differing liver disease severity

scientific article published in January 2002

Excess mortality rates in a cohort of patients infected with the hepatitis C virus: a prospective study.

scientific article

FibroGENE: A gene-based model for staging liver fibrosis

scientific article published on 16 November 2015

Guidelines on prevention of transmission of hepatitis C virus infection in the workplace: do they work in practice?

scientific article published in December 2007

HCV and PCR negativity

scientific article published in June 1992

HCV treatment rates and sustained viral response among people who inject drugs in seven UK sites: real world results and modelling of treatment impact.

scientific article published on 7 October 2014

Hepatic elastin content is predictive of adverse outcome in advanced fibrotic liver disease

scientific article published on 21 February 2018

Hepatitis C - Assessment to Treatment Trial (HepCATT) in primary care: study protocol for a cluster randomised controlled trial

scientific article published on 29 July 2016

Hepatitis C in blood donors

scientific article published in March 1993

Hepatitis C patient-derived glycoproteins exhibit marked differences in susceptibility to serum neutralizing antibodies: genetic subtype defines antigenic but not neutralization serotype.

scientific article

Hepatitis C virus infection in multi-transfused children with haematological malignancy.

scientific article published in October 1995

Hepatitis E: An emerging infection in high income countries.

scientific article published on 11 December 2013

Hepatitis G infection: role in cryptogenic chronic liver disease and primary liver cell cancer in the UK. Trent Hepatitis C virus Study Group.

scientific article published on May 1998

Hepatitis G virus infection in lymphoma and in blood donors.

scientific article published on September 1998

Host genetic factors associated with hepatocellular carcinoma in patients with hepatitis C virus infection: A systematic review.

scientific article published on 3 February 2018

Human herpesvirus-6

scientific article published in 1992

Human parainfluenza 2 & 4: Clinical and genetic epidemiology in the UK, 2013–2017, reveals distinct disease features and co‐circulating genomic subtypes

scientific article published in 2022

IFN-λ3, not IFN-λ4, likely mediates IFNL3-IFNL4 haplotype-dependent hepatic inflammation and fibrosis

scientific article published on 10 April 2017

IFNL3 polymorphisms predict response to therapy in chronic hepatitis C genotype 2/3 infection

scientific article published on 24 April 2014

IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic hepatitis C virus infection in a European Cohort: a cross-sectional study

scientific article

INTRADERMAL VACCINATION AGAINST HEPATITIS B

scientific article published in The Lancet

Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort

scientific article

Identification of type-specific domains within glycoprotein G of herpes simplex virus type 2 (HSV-2) recognized by the majority of patients infected with HSV-2, but not by those infected with HSV-1.

scientific article

Immunisation with phage displaying peptides representing single epitopes of the glycoprotein G can give rise to partial protective immunity to HSV-2.

scientific article

Impact Of Direct Acting Antiviral Agents On Liver Function In Patients With Chronic Hepatitis C Virus Infection

scientific article published on 26 September 2020

Impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis

scientific article published on 29 January 2016

In silico and in vitro interrogation of a widely used HEV RT-qPCR assay for detection of the species Orthohepevirus A.

scientific article published on 18 December 2014

Interferon lambda 4 impacts the genetic diversity of hepatitis C virus

scientific article published on 03 September 2019

Interferon plus amantadine versus interferon alone in the treatment of naı̈ve patients with chronic hepatitis C: a UK multicentre study

article

Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease.

scientific article

Is increased hepatitis C virus case-finding combined with current or 8-week to 12-week direct-acting antiviral therapy cost-effective in UK prisons? A prevention benefit analysis

scientific article published on 10 February 2016

MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C.

scientific article published on 15 September 2016

Mannan binding lectin and viral hepatitis

scientific article published on 20 November 2006

Modulation of Epstein-Barr virus-induced B-cell activation by concanavalin A.

scientific article

Multiplex protein analysis to determine fibrosis stage and progression in patients with chronic hepatitis C.

scientific article

Naturally occurring antibodies that recognize linear epitopes in the amino terminus of the hepatitis C virus E2 protein confer noninterfering, additive neutralization

scientific article (publication date: March 2012)

Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans

scientific article published on September 2012

Outcomes after successful direct-acting antiviral therapy for patients with chronic hepatitis C and decompensated cirrhosis

scientific article published on 4 July 2016

Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Service: A Mixed-Methods Study

scientific article published on 29 December 2020

Playing in a scrapyard and acute renal failure.

scientific article published on May 1997

Predictors of hepatitis C treatment response: what's new?

scientific article published on 03 January 2014

Pretreatment Lesions on Magnetic Resonance Imaging in Patients With Hepatitis C Virus Infection Diagnosed With Hepatocellular Carcinoma After Initiating Direct-Acting Antiviral Therapy

scientific article published on 03 April 2018

Prevalence and risk factors for hepatitis C virus infection in Kech District, Balochistan, Pakistan: most infections remain unexplained. A cross-sectional study.

scientific article published on 15 June 2011

Prevalence of a history of prior varicella/herpes zoster infection in multiple sclerosis

scientific article published on 11 September 2017

Production of IgM antibody to HHV6 in reactivation and primary infection

scientific article published on April 1990

Reasons for nonuse of antiviral treatment in patients with chronic hepatitis C infection and thrombocytopaenia: a retrospective chart review from five European countries

scientific article

Recent advances in immunity to viruses, immunization, and vaccination

article

Receptors for mouse erythrocytes on human lymphocytes: technical aspects

scientific article published on April 1984

Recombinant human L-ficolin directly neutralizes hepatitis C virus entry.

scientific article published on 15 May 2014

Reduced healthcare utilization following successful hepatitis C virus treatment in HIV-co-infected patients with mild liver disease

scientific article published on 29 October 2015

Repair of chemical carcinogen-induced damage in DNA of human lymphocytes and lymphoid cell lines--studies of the kinetics of removal of O6-methylguanine and 3-methyladenine.

scientific article published in January 1986

Reply to: No effect of resistance-associated substitutions in patients with rare HCV subtypes following treatment with sofosbuvir-containing regimens.

scientific article published on 12 January 2018

Response to DAA therapy in the NHS England Early Access Programme for rare HCV subtypes from low and middle income countries

scientific article

SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis.

scientific article published on 6 November 2017

Sentinel laboratory surveillance of hepatitis C antibody testing in England: understanding the epidemiology of HCV infection

article

Serum HCV RNA levels assessed by quantitative NASBA: stability of viral load over time, and lack of correlation with liver disease. The Trent HCV Study Group

scientific article published on September 1996

Serum autoantibody measurement for the detection of hepatocellular carcinoma

scientific article

Severe fibrosis in hepatitis C virus-infected patients is associated with increased activity of the mannan-binding lectin (MBL)/MBL-associated serine protease 1 (MASP-1) complex

scientific article

Studies to show that with podophyllotoxin the early replicative stages of herpes simplex virus type 1 depend upon functional cytoplasmic microtubules

scientific article published in September 1996

TT virus infection in patients with hepatitis C: frequency, persistence, and sequence heterogeneity

scientific article published in July 1999

TT virus sequence heterogeneity in vivo: evidence for co-infection with multiple genetic types.

scientific article published in July 1999

Testing for hepatitis C virus infection in UK prisons: What actually happens?

scientific article published on 27 February 2019

The Hepatitis C Awareness Through to Treatment (HepCATT) study: improving the cascade of care for hepatitis C virus-infected people who inject drugs in England

scientific article published on 12 March 2019

The Nuclear Arms Race and the Third World

scientific article published in The Journal of the American Medical Association

The association between hepatocellular carcinoma and direct-acting anti-viral treatment in patients with decompensated cirrhosis

scientific article published on 31 May 2019

The cost of treatment failure: resource use and costs incurred by hepatitis C virus genotype 1-infected patients who do or do not achieve sustained virological response to therapy.

scientific article published on August 2013

The effectiveness of daclatasvir based therapy in European patients with chronic hepatitis C and advanced liver disease

scientific article

The effects of cyclosporin A on the early responses of B and T cells to Epstein-Barr virus infection

scientific article

The natural history of hepatitis C with severe hepatic fibrosis

article

The presence of rheumatoid factor in sera from anti-HCV positive blood donors interferes with the detection of HCV-specific IgM

article

The reliability of serological tests for the diagnosis of genital herpes: a critique

article

The role of the virology laboratory in the management of hepatitis C virus infection

scientific article published in July 2002

The treatment of HCV in patients with haemoglobinopathy in Kurdistan Region, Iraq: a single centre experience

scientific article published on June 2016

Understanding hepatitis C intervention success: Qualitative findings from the HepCATT study

scientific article published on 25 January 2018

Use of anti-GOR testing in the screening of blood donors for hepatitis C virus infection.

scientific article published in January 1993

Use of short tandem repeat fingerprinting to validate sample origins in hepatitis C virus molecular epidemiology studies

scientific article published on 7 October 2013

Variation in expression of mouse erythrocyte receptors on Epstein-Barr virus-induced B-cell lines.

scientific article published in January 1984

Vertical transmission of hepatitis C.

scientific article published in April 1995

Virus infections in pregnancy

aMAP risk score predicts hepatocellular carcinoma development in patients with chronic hepatitis

scientific article published on 21 July 2020

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