List of works - Shigeo Murata

Loss of autophagy in the central nervous system causes neurodegeneration in mice

scientific article (publication date: 15 June 2006)

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

scientific journal article

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

scientific article

T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ

scientific article published in Nature

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

scientific article

A ubiquitin ligase complex assembles linear polyubiquitin chains

scientific article

CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein

scientific article published on 21 November 2001

Regulation of CD8+ T cell development by thymus-specific proteasomes

scientific journal article

Molecular mechanisms of proteasome assembly

scientific article

Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes

scientific article published on 21 January 2005

A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes

scientific article

Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones

scientific article

Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process

scientific article published on 15 December 2008

CHIP: a quality-control E3 ligase collaborating with molecular chaperones

scientific article

A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans

scientific article

A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes

scientific article

Proteasome assembly defect due to a proteasome subunit beta type 8 (PSMB8) mutation causes the autoinflammatory disorder, Nakajo-Nishimura syndrome.

scientific article

Critical role of PA28 in hepatitis C virus-associated steatogenesis and hepatocarcinogenesis

scientific article

Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity

scientific article

Proteasome activator PA28gamma-dependent nuclear retention and degradation of hepatitis C virus core protein

scientific article

In vivo evidence of CHIP up-regulation attenuating tau aggregation

scientific article

Immunoproteasome assembly and antigen presentation in mice lacking both PA28alpha and PA28beta.

scientific article

Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptor

scientific article

Thymoproteasome shapes immunocompetent repertoire of CD8+ T cells

scientific article

Growth retardation in mice lacking the proteasome activator PA28gamma

scientific article published on 01 December 1999

Structural basis for distinct roles of Lys63- and Lys48-linked polyubiquitin chains.

scientific article published in October 2004

Involvement of the PA28 -Dependent Pathway in Insulin Resistance Induced by Hepatitis C Virus Core Protein

scientific article

17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse

scientific article

Dissecting beta-ring assembly pathway of the mammalian 20S proteasome.

scientific article published on 24 July 2008

Cooperation of multiple chaperones required for the assembly of mammalian 20S proteasomes

scientific article

Decreased Proteasomal Activity Causes Age-Related Phenotypes and Promotes the Development of Metabolic Abnormalities

scientific article published on 30 December 2011

Sterol regulatory element-binding proteins are negatively regulated through SUMO-1 modification independent of the ubiquitin/26 S proteasome pathway

scientific article published on 2 March 2003

Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells.

scientific article published on 13 August 2013

Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes

scientific article

Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver

scientific article published on 3 December 2012

Thymoproteasome: probable role in generating positively selecting peptides

scientific article published on 09 April 2008

Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells

scientific article published on 29 May 2013

Rpn10-mediated degradation of ubiquitinated proteins is essential for mouse development

scientific article

The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction

scientific article published on 16 August 2016

An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis

scientific article

Thymic microenvironments for T-cell repertoire formation

scientific article published on January 2008

PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis

scientific journal article

Ontogeny of thymic cortical epithelial cells expressing the thymoproteasome subunit β5t

scientific article published on 14 April 2011

Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit beta5t

scientific article

Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I {alpha}.

scientific article published on 14 March 2005

Two distinct pathways mediated by PA28 and hsp90 in major histocompatibility complex class I antigen processing

scientific article

Role of thymic cortex-specific self-peptides in positive selection of T cells

scientific article published on 26 May 2010

Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis.

scientific article published on 29 July 2015

Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome

scientific article published on 6 March 2014

Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes

scientific article

List of works by Shigeo Murata

Loss of autophagy in the central nervous system causes neurodegeneration in mice

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

A ubiquitin ligase complex assembles linear polyubiquitin chains

CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein

Regulation of CD8+ T cell development by thymus-specific proteasomes

Molecular mechanisms of proteasome assembly

Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes

A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes

Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones

Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process

CHIP: a quality-control E3 ligase collaborating with molecular chaperones

A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans

A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes

Proteasome assembly defect due to a proteasome subunit beta type 8 (PSMB8) mutation causes the autoinflammatory disorder, Nakajo-Nishimura syndrome.

Critical role of PA28 in hepatitis C virus-associated steatogenesis and hepatocarcinogenesis

Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity

Proteasome activator PA28gamma-dependent nuclear retention and degradation of hepatitis C virus core protein

In vivo evidence of CHIP up-regulation attenuating tau aggregation

Immunoproteasome assembly and antigen presentation in mice lacking both PA28alpha and PA28beta.

Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptor

Thymoproteasome shapes immunocompetent repertoire of CD8+ T cells

Growth retardation in mice lacking the proteasome activator PA28gamma

Structural basis for distinct roles of Lys63- and Lys48-linked polyubiquitin chains.

Involvement of the PA28 -Dependent Pathway in Insulin Resistance Induced by Hepatitis C Virus Core Protein

17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse

Dissecting beta-ring assembly pathway of the mammalian 20S proteasome.

Cooperation of multiple chaperones required for the assembly of mammalian 20S proteasomes

Decreased Proteasomal Activity Causes Age-Related Phenotypes and Promotes the Development of Metabolic Abnormalities

Sterol regulatory element-binding proteins are negatively regulated through SUMO-1 modification independent of the ubiquitin/26 S proteasome pathway

Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells.

Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes

Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver

Thymoproteasome: probable role in generating positively selecting peptides

Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells

Rpn10-mediated degradation of ubiquitinated proteins is essential for mouse development

The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction

An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis

Thymic microenvironments for T-cell repertoire formation

PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis

Ontogeny of thymic cortical epithelial cells expressing the thymoproteasome subunit β5t

Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit beta5t

Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I {alpha}.

Two distinct pathways mediated by PA28 and hsp90 in major histocompatibility complex class I antigen processing

Role of thymic cortex-specific self-peptides in positive selection of T cells

Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis.

Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome

Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes