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List of works by Harry W M Steinbusch

5,7-DHT lesion of the dorsal raphe nuclei impairs object recognition but not affective behavior and corticosterone response to stressor in the rat.

scientific article published on 19 December 2005

5-HTT independent effects of fluoxetine on neuroplasticity

A combined in vivo neurochemical and electrophysiological analysis of the effect of high-frequency stimulation of the subthalamic nucleus on 5-HT transmission

scientific article published on 8 September 2011

A single course of antenatal betamethasone reduces neurotrophic factor S100B concentration in the hippocampus and serum in the neonatal rat

scientific journal article

Accumulation of nuclear DNA damage or neuron loss: molecular basis for a new approach to understanding selective neuronal vulnerability in neurodegenerative diseases

scientific article

Acute and separate modulation of motor and cognitive performance in parkinsonian rats by bilateral stimulation of the subthalamic nucleus

scientific article published on May 2005

Acute seizure-suppressing effect of vagus nerve stimulation in the amygdala kindled rat.

scientific article published on 14 January 2010

Acute tryptophan depletion in C57BL/6 mice does not induce central serotonin reduction or affective behavioural changes

scientific article published on 28 August 2009

Acute tryptophan depletion potentiates 3,4-methylenedioxymethamphetamine-induced cerebrovascular hyperperfusion in adult male Wistar rats

scientific article published in May 2010

Advanced microscopy techniques for quantitative analysis in neuromorphology and neuropathology research: current status and requirements for the future

scientific article

Age-related changes of neuron numbers in the frontal cortex of a transgenic mouse model of Alzheimer's disease

scientific article

Age-related increase in levels of 5-hydroxymethylcytosine in mouse hippocampus is prevented by caloric restriction

scientific article published on June 2012

Age-related loss of synaptophysin immunoreactive presynaptic boutons within the hippocampus of APP751SL, PS1M146L, and APP751SL/PS1M146L transgenic mice

scientific article

Alterations in the cholinergic system after frontal cortical infarction in rat brain: pharmacological magnetic resonance imaging of muscarinic receptor responsiveness and stereological analysis of cholinergic forebrain neurons

scientific article published on 23 May 2011

Altered expression of neuronal tryptophan hydroxylase-2 mRNA in the dorsal and median raphe nuclei of three genetically modified mouse models relevant to depression and anxiety

scientific article published on 15 June 2011

Altered gene expression and neuropathology in Alzheimer's disease

scientific article published on 18 August 2005

An in vitro and in vivo study of peptide-functionalized nanoparticles for brain targeting: The importance of selective blood-brain barrier uptake

scientific article published on 21 November 2016

Anhedonic-like traits and lack of affective deficits in 18-month-old C57BL/6 mice: Implications for modeling elderly depression

scientific article published on 11 May 2012

Antioxidants and Alzheimer's disease: from bench to bedside (and back again).

scientific article

Are Dopamine Oxidation Metabolites Involved in the Loss of Dopaminergic Neurons in the Nigrostriatal System in Parkinson's Disease?

scientific article published on 24 February 2017

Attenuation of fear-like response by escitalopram treatment after electrical stimulation of the midbrain dorsolateral periaqueductal gray

scientific article published on September 15, 2010

Autism: neuropathology, alterations of the GABAergic system, and animal models

scientific article

Basic fibroblast growth factor, glutamine synthetase, and interleukin-6 in vitreous fluid from eyes with retinal detachment complicated by proliferative vitreoretinopathy

scientific article

Bilateral high frequency stimulation of the subthalamic nucleus normalizes COX activity in the substantia nigra of Parkinsonian rats

scientific article published on 9 July 2009

Brain apoptosis and carotid artery reactivity in fetal asphyctic preconditioning

scientific article published in January 2010

Buspirone-induced changes in the serotonergic and non-serotonergic cells in the dorsal raphe nucleus of rats

scientific article published on 21 February 2010

Caloric restriction and aging but not overexpression of SOD1 affect hippocampal volumes in mice

scientific article published on 20 August 2010

Carbon dioxide inhalation as a human experimental model of panic: the relationship between emotions and cardiovascular physiology

scientific article

Cerebellar nuclei are involved in impulsive behaviour.

scientific article published on 18 May 2009

Cerebral Pathology and Cognition in Diabetes: The Merits of Multiparametric Neuroimaging

scientific article

Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice

scientific article published on June 2011

Cerebral and Retinal Neurovascular Changes: A Biomarker for Alzheimer's Disease

scientific article published in August 2017

Cerebral inflammation and mobilization of the peripheral immune system following global hypoxia-ischemia in preterm sheep

scientific article published on 24 January 2013

Chlamydia pneumoniae infection of brain cells: an in vitro study

scientific article published on 18 April 2006

Chorioamnionitis induced by intraamniotic lipopolysaccharide resulted in an interval-dependent increase in central nervous system injury in the fetal sheep.

scientific article published on 14 February 2009

Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease

scientific article published on 4 July 2012

Close communication between the subependymal serotonergic plexus and the neurogenic subventricular zone

scientific article published on September 10, 2011

Cognition- and anxiety-related behavior, synaptophysin and MAP2 immunoreactivity in the adult rat treated with a single course of antenatal betamethasone.

scientific article

Complement activation by ceramide transporter proteins

scientific article published on 6 January 2014

Concomitant manipulation of murine NMDA- and AMPA-receptors to produce pro-cognitive drug effects in mice

scientific article published on 7 August 2013

Current concepts in Alzheimer's Disease: molecules, models and translational perspectives

scientific article published on 22 October 2013

Cytokine changes and tryptophan metabolites in medication-naïve and medication-free schizophrenic patients.

scientific article published on 22 April 2009

DNMT3A moderates cognitive decline in subjects with mild cognitive impairment: replicated evidence from two mild cognitive impairment cohorts

scientific article published in June 2015

Deep brain stimulation of the forniceal area enhances memory functions in experimental dementia: The role of stimulation parameters

scientific article published on February 23, 2012

Deep brain stimulation of the nucleus accumbens core and shell: opposite effects on impulsive action

scientific article published on 29 July 2008

Deep brain stimulation of the nucleus accumbens shell increases impulsive behavior and tissue levels of dopamine and serotonin

scientific article published on 11 July 2010

Defeat stress in rodents: From behavior to molecules

scientific article published on 14 October 2015

Delivery of DNA into the central nervous system via electroporation

scientific article published on January 2014

Delivery of peptide and protein drugs over the blood-brain barrier

scientific article published on 24 January 2009

Depressive symptoms following interferon-α therapy: mediated by immune-induced reductions in brain-derived neurotrophic factor?

scientific article published on 29 July 2010

Detection of Peptide-based nanoparticles in blood plasma by ELISA

scientific article

Detection of amyloid beta aggregates in the brain of BALB/c mice after Chlamydia pneumoniae infection

scientific article

Developmental exposure to SSRIs, in addition to maternal stress, has long-term sex-dependent effects on hippocampal plasticity

scientific article published on 12 October 2014

Developmental fluoxetine exposure and prenatal stress alter sexual differentiation of the brain and reproductive behavior in male rat offspring

scientific article published on 8 February 2013

Developmental fluoxetine exposure facilitates sexual behavior in female offspring

scientific article published on 31 July 2013

Developmental fluoxetine exposure increases behavioral despair and alters epigenetic regulation of the hippocampal BDNF gene in adult female offspring

scientific article published in February 2016

Dietary intake of plant sterols stably increases plant sterol levels in the murine brain

scientific article published on 25 January 2012

Differential distribution of hypoxia-inducible factor 1-beta (ARNT or ARNT2) in mouse substantia nigra and ventral tegmental area

scientific article published on 10 July 2014

Differential effects of prenatal stress in 5-Htt deficient mice: towards molecular mechanisms of gene × environment interactions

scientific article

Dimebon enhances hippocampus-dependent learning in both appetitive and inhibitory memory tasks in mice

scientific article published on 14 December 2010

Dissecting the projections of different groups of raphe serotonergic neurons (Commentary on Bang et al.)

scientific article published on January 1, 2012

Dissociable effects in reaction time performance after unilateral cerebral infarction: a comparison between the left and right frontal cortices in rats

scientific article published on 17 January 2006

Distribution of dopaminergic cell bodies in the median raphe nucleus of the rat brain

scientific article published on 16 October 2013

Distributions of hypothalamic neuron populations coexpressing tyrosine hydroxylase and the vesicular GABA transporter in the mouse

scientific article published on 16 January 2020

Efavirenz induces depressive-like behaviour, increased stress response and changes in the immune response in rats

scientific article published on January 2005

Effect of buspirone on the behavioral regulation of rats in low versus high anxiety conditions

scientific article published on January 2008

Effect of the COX-2 inhibitor celecoxib on behavioural and immune changes in an olfactory bulbectomised rat model of depression

scientific article published on 21 August 2007

Effects of prenatal Poly I:C exposure on global histone deacetylase (HDAC) and DNA methyltransferase (DNMT) activity in the mouse brain

scientific article published on 23 May 2016

Effects of right-hemisphere cortical infarction and muscarinic acetylcholine receptor blockade on spatial visual attention performance in rats

scientific article published on 28 December 2006

Effects of subcutaneous LPS injection on gestational length and intrauterine and neonatal mortality in mice

scientific article published on 22 January 2015

Electrical stimulation of the motor cortex enhances progenitor cell migration in the adult rat brain

scientific article published on 4 September 2013

Epigenetic epidemiology in psychiatry: A translational neuroscience perspective

scholarly article by Ehsan Pishva et al published 1 January 2012 in Translational neuroscience

Epigenetic modifications in mouse cerebellar Purkinje cells: effects of aging, caloric restriction, and overexpression of superoxide dismutase 1 on 5-methylcytosine and 5-hydroxymethylcytosine

scientific article published on 8 August 2015

Epigenetic regulation in the pathophysiology of Alzheimer's disease

scientific article published on 25 January 2010

Evaluation of 3-nitrotyrosine as a marker for 3-nitropropionic acid-induced oxidative stress in Lewis and Wistar rats and strain-specific whole brain spheroid cultures

scientific article published in March 2002

Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function

scientific article

Expression of monoamine transporters, nitric oxide synthase 3, and neurotrophin genes in antidepressant-stimulated astrocytes

scientific article published on 20 April 2012

Fetal asphyctic preconditioning protects against perinatal asphyxia- induced apoptosis and astrogliosis in neonatal brain

scientific article published on January 2015

Fetal asphyxia leads to a decrease in dorsal raphe serotonergic neurons

scientific article

Fos immunoreactivity in the rat forebrain induced by electrical stimulation of the dorsolateral periaqueductal gray matter

scientific article published on 7 July 2009

Functional investigations into the role of dopamine and serotonin in partial bilateral striatal 6-hydroxydopamine lesioned rats

scientific article published on 28 February 2006

Gene regulation by hypoxia and the neurodevelopmental origin of schizophrenia

scientific article (publication date: June 2006)

Gene-environment interaction research and transgenic mouse models of Alzheimer's disease

scientific article

Gestational stress in mouse dams negatively affects gestation and postpartum hippocampal BDNF and P11 protein levels

scientific article published on 28 February 2018

Gestational stress leads to depressive-like behavioural and immunological changes in the rat

scientific journal article

Goodpasture antigen-binding protein/ceramide transporter binds to human serum amyloid P-component and is present in brain amyloid plaques

scientific article published on 6 March 2012

High-frequency stimulation of the dorsolateral periaqueductal gray and ventromedial hypothalamus fails to inhibit panic-like behaviour

scientific article published on 4 June 2008

Hippocampal interneuron loss in an APP/PS1 double mutant mouse and in Alzheimer's disease

scientific article

Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease

scientific article

Histone deacetylase 2 in the mouse hippocampus: attenuation of age-related increase by caloric restriction

scientific article published on October 2013

Hyperdopaminergic status in experimental Huntington disease

scientific article published on September 2010

Hypomobility after DOI administration can be reversed by subthalamic nucleus deep brain stimulation

scientific article published on 17 July 2007

In vivo electroporation of the central nervous system: a non-viral approach for targeted gene delivery

scientific article published on 16 October 2010

In vivo visualization of vascular leakage in photochemically induced cortical infarction

scientific article published in January 2005

Increased electrical and metabolic activity in the dorsal raphe nucleus of Parkinsonian rats

scientific article published on 18 May 2008

Increased number of TH-immunoreactive cells in the ventral tegmental area after deep brain stimulation of the anterior nucleus of the thalamus

scientific article published on 30 July 2014

Increased number of cerebellar granule cells and astrocytes in the internal granule layer in sheep following prenatal intra-amniotic injection of lipopolysaccharide

scientific article published in March 2012

Increased plasma corticosterone levels after periaqueductal gray stimulation-induced escape reaction or panic attacks in rats

scientific article published on 24 December 2010

Influence of antidepressants on intracellular levels of cyclic adenosine monophosphate in human peripheral blood mononuclear cells

scientific article published on January 2003

Inhibition of 5-HT neuron activity and induction of depressive-like behavior by high-frequency stimulation of the subthalamic nucleus

scholarly article

Inhibition of phoshodiesterase type 2 or type 10 reverses object memory deficits induced by scopolamine or MK-801.

scientific article published on 19 August 2012

Kynurenine pathway in major depression: Evidence of impaired neuroprotection

article

Limitations in transplantation of astroglia-biomatrix bridges to stimulate corticospinal axon regrowth across large spinal lesion gaps

scientific article published on 13 March 2006

Liver X receptor activation restores memory in aged AD mice without reducing amyloid

scientific article published on 11 August 2009

Localization and characterization of cGMP-immunoreactive structures in rat brain slices after NO-dependent and NO-independent stimulation of soluble guanylyl cyclase.

scientific article

Localization of mutant ubiquitin in the brain of a transgenic mouse line with proteasomal inhibition and its validation at specific sites in Alzheimer's disease

scientific article

Long-term corticosterone exposure decreases insulin sensitivity and induces depressive-like behaviour in the C57BL/6NCrl mouse

scientific article

Low Current-driven Micro-electroporation Allows Efficient In Vivo Delivery of Nonviral DNA into the Adult Mouse Brain

scientific article published on June 2008

Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis

scientific article published in September 2009

Lowering the dose of antenatal steroids: the effects of a single course of betamethasone on somatic growth and brain cell proliferation in the rat.

scientific article published on 31 March 2006

Major depression, cognitive dysfunction and Alzheimer's disease: is there a link?

scientific article published on 20 October 2009

Maternal stress-induced reduction in birth weight as a marker for adult affective state

scientific article published in January 2010

Mean cell spacing abnormalities in the neocortex of patients with schizophrenia

scientific article published in January 2005

Measuring behavior in mice with chronic stress depression paradigm

scientific article published on 22 December 2009

Metabolic and electrophysiological changes in the basal ganglia of transgenic Huntington's disease rats

scientific article published on 17 July 2012

Microvessel length density, total length, and length per neuron in five subcortical regions in schizophrenia

scientific article

Mild dopaminergic lesions are accompanied by robust changes in subthalamic nucleus activity

scientific article published on December 22, 2011

Minicolumnar abnormalities in autism

scientific article

Monopolar versus bipolar high frequency stimulation in the rat subthalamic nucleus: differences in histological damage

scientific article published in August 2004

Motor and cognitive improvement by deep brain stimulation in a transgenic rat model of Huntington's disease

scientific article published on 14 August 2006

Motor and non-motor behaviour in experimental Huntington's disease

scientific article published on 5 October 2011

Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3)

scientific article

Mutant ubiquitin decreases amyloid β plaque formation in a transgenic mouse model of Alzheimer’s disease

scientific article published on July 14, 2012

Neuronal distribution in the neocortex of schizophrenic patients

scientific article published on 20 February 2008

Neuronal serotonin release triggers the heat shock response in C. elegans in the absence of temperature increase

scientific article

Neurons in the fusiform gyrus are fewer and smaller in autism

scientific article

Neuropsychiatric disorders related to interferon and interleukins treatment

scientific article published on 10 December 2008

Neurostimulatory and ablative treatment options in major depressive disorder: a systematic review

scientific article

No alterations of hippocampal neuronal number and synaptic bouton number in a transgenic mouse model expressing the beta-cleaved C-terminal APP fragment

scientific article published in March 2003

No effect of acute tryptophan depletion on phosphodiesterase inhibition--related improvements of short-term object memory in male Wistar rats

scientific article

Nucleus accumbens and impulsivity

scientific article

Object recognition testing: Statistical considerations

scientific article published on March 28, 2012

Object recognition testing: methodological considerations on exploration and discrimination measures.

scientific article

Object recognition testing: rodent species, strains, housing conditions, and estrous cycle

scientific article published on 28 March 2012

Periaqueductal grey stimulation induced panic-like behaviour is accompanied by deactivation of the deep cerebellar nuclei.

scientific article published on March 2011

Perinatal asphyxia induced neuronal loss by apoptosis in the neonatal rat striatum: a combined TUNEL and stereological study.

scientific article

Pharmacological magnetic resonance imaging of muscarinic acetylcholine receptor activation in rat brain

scientific article published on 19 March 2010

Phosphodiesterase 2 and 5 inhibition attenuates the object memory deficit induced by acute tryptophan depletion

scientific article published on 21 October 2008

Phosphodiesterase type 5 (PDE5) inhibition improves object recognition memory: indications for central and peripheral mechanisms

scientific article published on 8 March 2012

Phosphodiesterase type 5 inhibition improves early memory consolidation of object information

scientific article published in November 2004

Premature responding following bilateral stimulation of the rat subthalamic nucleus is amplitude and frequency dependent

scientific article published on May 2004

Prenatal maternal paroxetine treatment and neonatal mortality in the rat: a preliminary study.

scientific article published on 25 July 2007

Prenatal stress and early-life exposure to fluoxetine have enduring effects on anxiety and hippocampal BDNF gene expression in adult male offspring

scientific article published on 26 November 2015

Prenatal stress and subsequent exposure to chronic mild stress influence dendritic spine density and morphology in the rat medial prefrontal cortex.

scientific article

Prenatal stress reduces S100B in the neonatal rat hippocampus.

scientific article published in July 2006

Presenilin 1-related alterations in DNA integrity in a transgenic mouse model of Alzheimer's disease

scientific article published on 23 December 2009

Progressive deterioration of reaction time performance and choreiform symptoms in a new Huntington's disease transgenic ratmodel

scientific article published on 29 March 2006

Protection of nigral cell death by bilateral subthalamic nucleus stimulation

scientific article published on 26 September 2006

Quinolinic acid-immunoreactivity in the naïve mouse brain

scientific article published on 11 December 2015

REGION-SPECIFIC NEURON AND SYNAPSE LOSS IN THE HIPPOCAMPUS OF APPSL/PS1 KNOCK-IN MICE

scientific article

Role of TNF-alpha during central sensitization in preclinical studies

scientific article

Rolipram improves cognition, reduces anxiety- and despair-like behaviors and impacts hippocampal neuroplasticity after transient global cerebral ischemia

scientific article published on 4 April 2016

Selective phosphodiesterase inhibitors: a promising target for cognition enhancement.

scientific article published on 16 August 2008

Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats

scientific article published on 9 February 2006

Species differences in the localization of cGMP-producing and NO-responsive elements in the mouse and rat hippocampus using cGMP immunocytochemistry.

scientific article published in April 2004

Specificity of Chicken (IgY) versus Rabbit (IgG) Antibodies Raised against Cholecystokinin Octapeptide (CCK-8)

scientific article published on 01 January 1996

Stability of interleukin 6, soluble interleukin 6 receptor, interleukin 10 and CC16 in human serum

scientific article published in September 2002

Stereological studies of capillary length density in the frontal cortex of schizophrenics

scientific article published on 10 May 2005

Stimulation of neurite outgrowth on neonatal cerebral astrocytes is enhanced in the presence of BDNF.

scientific article published on 15 September 2006

Stress and the pregnant female: Impact on hippocampal cell proliferation, but not affective-like behaviors.

scientific article published on 3 March 2011

Stress-mediated decreases in brain-derived neurotrophic factor as potential confounding factor for acute tryptophan depletion-induced neurochemical effects.

scientific article published on 28 July 2009

Systemic G-CSF attenuates cerebral inflammation and hypomyelination but does not reduce seizure burden in preterm sheep exposed to global hypoxia-ischemia

scientific article published on 8 October 2013

T-helper types 1, 2, and 3 cytokine interactions in symptomatic manic patients

scientific article published on 01 December 2004

Th1, Th2, and Th3 cytokine alterations in major depression

scientific article published in October 2005

The aging brain: accumulation of DNA damage or neuron loss?

scientific article

The aging brain: less neurons could be better

scientific article

The assessment of locomotor function in spinal cord injured rats: the importance of objective analysis of coordination

scientific article published on 01 February 2005

The ceramide transporter and the Goodpasture antigen binding protein: one protein--one function?

scientific article published on 17 March 2010

The dorsal raphe nucleus and serotonin: implications for neuroplasticity linked to major depression and Alzheimer's disease

scientific article published on January 2008

The dorsal raphe nucleus--from silver stainings to a role in depression

scientific article published on 17 January 2007

The functional role of the subthalamic nucleus in cognitive and limbic circuits

scientific article

The marginal division of the striatum and hippocampus has different role and mechanism in learning and memory

scientific article

The negative immunoregulatory effects of fluoxetine in relation to the cAMP-dependent PKA pathway

scientific article

The neuronal insulin sensitizer dicholine succinate reduces stress-induced depressive traits and memory deficit: possible role of insulin-like growth factor 2.

scientific article

The olfactory bulbectomized rat model is not an appropriate model for studying depression based on morphological/stereological studies of the hippocampus

scientific article

The phosphodiesterase type 2 inhibitor BAY 60-7550 reverses functional impairments induced by brain ischemia by decreasing hippocampal neurodegeneration and enhancing hippocampal neuronal plasticity

scientific article published on 4 November 2016

The structural basis for understanding human brain function and dysfunction

scientific article published in December 2003

The subthalamic nucleus: From response selection to execution

scientific article

TrkB in the hippocampus and nucleus accumbens differentially modulates depression-like behavior in mice

scientific article published on 24 August 2015

Tryptophan breakdown pathway in bipolar mania

scientific article

Vascular Contributions in Alzheimer's Disease-Related Neuropathological Changes: First Autopsy Evidence from a South Asian Aging Population

scientific article published on 2 September 2016

Volume, neuron density and total neuron number in five subcortical regions in schizophrenia

scientific article published on 15 February 2007

cGMP, but not cAMP, in rat hippocampus is involved in early stages of object memory consolidation

scientific article published in February 2002

mRNA expression patterns of the cGMP‐hydrolyzing phosphodiesterases types 2, 5, and 9 during development of the rat brain

scientific article published on December 22, 2003