List of works - Andrea Ruecker

A high throughput screen for next-generation leads targeting malaria parasite transmission

scientific article published in Nature Communications

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

scientific article

A male and female gametocyte functional viability assay to identify biologically relevant malaria transmission-blocking drugs

scientific article

A novel multiple-stage antimalarial agent that inhibits protein synthesis

scientific article (publication date: 18 June 2015)

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance

scientific article published on 24 May 2017

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.

scientific article

Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria

scientific article

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling

scientific article

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis

scientific article published on 25 May 2016

Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans

scientific article

Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen

scientific article

Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation

scientific article published on 23 March 2015

Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs

scientific article published on 29 April 2013

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

scientific article (publication date: July 2016)

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

scientific article published on 14 September 2016

Proteolytic activation of the essential parasitophorous vacuole cysteine protease SERA6 accompanies malaria parasite egress from its host erythrocyte

scientific article

Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum

scientific article

Routine in vitro culture of P. falciparum gametocytes to evaluate novel transmission-blocking interventions.

scientific article published on 18 August 2016

List of works by Andrea Ruecker

A high throughput screen for next-generation leads targeting malaria parasite transmission

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

A male and female gametocyte functional viability assay to identify biologically relevant malaria transmission-blocking drugs

A novel multiple-stage antimalarial agent that inhibits protein synthesis

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.

Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis

Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans

Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen

Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation

Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

Proteolytic activation of the essential parasitophorous vacuole cysteine protease SERA6 accompanies malaria parasite egress from its host erythrocyte

Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum

Routine in vitro culture of P. falciparum gametocytes to evaluate novel transmission-blocking interventions.