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List of works by Katie J. Ewer

A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA

scientific article

A phase Ia study to assess the safety and immunogenicity of new malaria vaccine candidates ChAd63 CS administered alone and with MVA CS.

scientific article

A review of Phase I trials of Ebola virus vaccines: what can we learn from the race to develop novel vaccines?

scientific article (publication date: 26 May 2017)

Activation-induced Markers Detect Vaccine-Specific CD4⁺ T Cell Responses Not Measured by Assays Conventionally Used in Clinical Trials

article

An in vitro assay to measure antibody-mediated inhibition of P. berghei sporozoite invasion against P. falciparum antigens.

scientific article published on 5 December 2017

Analysis of human B-cell responses following ChAd63-MVA MSP1 and AMA1 immunization and controlled malaria infection

scientific article published on April 2014

Antigen mining with iterative genome screens identifies novel diagnostics for the Mycobacterium tuberculosis complex

scientific article published in January 2006

Assessment of chimpanzee adenovirus serotype 63 neutralizing antibodies prior to evaluation of a candidate malaria vaccine regimen based on viral vectors

scientific article

Assessment of humoral immune responses to blood-stage malaria antigens following ChAd63-MVA immunization, controlled human malaria infection and natural exposure

scientific article

Assessment of immune interference, antagonism, and diversion following human immunization with biallelic blood-stage malaria viral-vectored vaccines and controlled malaria infection

scientific article published on 4 January 2013

Assessment of novel vaccination regimens using viral vectored liver stage malaria vaccines encoding ME-TRAP.

scientific article published on 21 February 2018

Assessment of the Plasmodium falciparum Preerythrocytic Antigen UIS3 as a Potential Candidate for a Malaria Vaccine

scientific article published on 28 December 2016

CXCR3 T Follicular Helper Cells Induced by Co-Administration of RTS,S/AS01B and Viral-Vectored Vaccines Are Associated With Reduced Immunogenicity and Efficacy Against Malaria

scholarly article by Georgina Bowyer et al published 2018 in Frontiers in Immunology

ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans

scientific article

Characterisation of antigenic MHC Class I-restricted T cell epitopes in the glycoprotein of Ebolavirus

Characterization of Antigenic MHC-Class-I-Restricted T Cell Epitopes in the Glycoprotein of Ebolavirus

scientific article published on 01 November 2019

Characterization of a Mycobacterium tuberculosis peptide that is recognized by human CD4+ and CD8+ T cells in the context of multiple HLA alleles

scientific article

Characterization of two in vivo-expressed methyltransferases of the Mycobacterium tuberculosis complex: antigenicity and genetic regulation

scientific article

Chimpanzee adenoviral vectors as vaccines for outbreak pathogens

scientific article published on 30 October 2017

Clinical Evaluation Of New Viral Vectored Vaccines Targeting The Plasmodium Falciparum Blood-Stage Antigens; Msp1 And Ama1

scientific article published in 2011

Clinical assessment of a recombinant simian adenovirus ChAd63: a potent new vaccine vector

scientific article published on 24 January 2012

Co-infection with Schistosoma haematobium modulates the gene expression profile of malaria infection in schoolchildren in Gabon

scientific article published on 22 September 2014

Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates

scientific article published on 3 July 2015

Comparison of T-cell-based assay with tuberculin skin test for diagnosis of Mycobacterium tuberculosis infection in a school tuberculosis outbreak

scientific article

Correction for Nébié et al., Assessment of Chimpanzee Adenovirus Serotype 63 Neutralizing Antibodies Prior to Evaluation of a Candidate Malaria Vaccine Regimen Based on Viral Vectors.

scientific article

Cryopreservation-related loss of antigen-specific IFNγ producing CD4+ T-cells can skew immunogenicity data in vaccine trials: Lessons from a malaria vaccine trial substudy

scientific article

Deep Immune Phenotyping and Single-Cell Transcriptomics Allow Identification of Circulating TRM-Like Cells Which Correlate With Liver-Stage Immunity and Vaccine-Induced Protection From Malaria

scientific article published on 07 February 2022

Detection of Vaccine-Induced Antibodies to Ebola Virus in Oral Fluid

scientific article published on January 2016

Development of an in vitro Plasmodium parasite killing assay for the evaluation of cell-mediated immune responses following vaccination with pre-erythrocytic malaria vaccine candidates

scientific article published on 22 September 2014

Development of an in vitro assay and demonstration of Plasmodium berghei liver-stage inhibition by TRAP-specific CD8+ T cells

scientific article

Diagnosis of occult tuberculosis in hematological malignancy by enumeration of antigen-specific T cells

scientific article published on 01 February 2006

Diagnosis of tuberculosis

Diagnosis of tuberculosis in South African children with a T-cell-based assay: a prospective cohort study

scientific article

Dynamic Antigen-specific T-Cell Responses after Point-Source Exposure to Mycobacterium tuberculosis

article

Early diagnosis of subclinical multidrug-resistant tuberculosis

scientific article

Effect of BCG vaccination on risk of Mycobacterium tuberculosis infection in children with household tuberculosis contact: a prospective community-based study

scientific article published in October 2005

Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial

scientific article

Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial

scientific article

Enumeration of T cells specific for RD1-encoded antigens suggests a high prevalence of latent Mycobacterium tuberculosis infection in healthy urban Indians

scientific article published on 21 December 2000

Enzyme-linked immunospot and tuberculin skin testing to detect latent tuberculosis infection

scientific article

Evaluation of T-cell responses to novel RD1- and RD2-encoded Mycobacterium tuberculosis gene products for specific detection of human tuberculosis infection

scientific article published on May 2004

Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals

scientific article

Ex Vivo Characterization of Early Secretory Antigenic Target 6-Specific T Cells at Sites of Active Disease in Pleural Tuberculosis

scientific article published on 08 December 2004

First field efficacy trial of the ChAd63 MVA ME-TRAP vectored malaria vaccine candidate in 5-17 months old infants and children

scientific article published in PLoS ONE

Gene expression profiling and antigen mining of the tuberculin production strain Mycobacterium bovis AN5.

scientific article published on 25 July 2008

Humoral immunogenicity of ChAd63_MVA ME-TRAP vaccination in African infants and children.

scientific article published on 22 September 2014

Identification of Immunodominant Responses to the Plasmodium falciparum Antigens PfUIS3, PfLSA1 and PfLSAP2 in Multiple Strains of Mice

scientific article published on 11 December 2015

Immunogenicity of ChAd63 + MVA ME-TRAP in Senegalese adults.

scientific article published on 22 September 2014

Impact of a T cell-based blood test for tuberculosis infection on clinical decision-making in routine practice

scientific article

Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909.

scientific article

Is interleukin-4delta3 splice variant expression in bovine tuberculosis a marker of protective immunity?

scientific article published on 26 March 2007

Methods for Measuring T-Cell Memory to Vaccination: From Mouse to Man

scientific article published on 21 July 2018

Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

scientific article

Phase Ia clinical evaluation of the Plasmodium falciparum blood-stage antigen MSP1 in ChAd63 and MVA vaccine vectors

scientific article published on 23 August 2011

Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors

scientific article (publication date: 2012)

Potency assays for novel T-cell-inducing vaccines against malaria.

scientific article published on February 2009

Potent CD8+ T-cell immunogenicity in humans of a novel heterosubtypic influenza A vaccine, MVA-NP+M1.

scientific article

Prime and target immunization protects against liver-stage malaria in mice

scholarly article by Anita Gola et al published 26 September 2018 in Science Translational Medicine

Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults

scientific article

Prime-boost vectored malaria vaccines: progress and prospects

scientific article published on 18 January 2010

Progress with viral vectored malaria vaccines: A multi-stage approach involving "unnatural immunity".

scientific article

Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation

scientific article published on January 2013

Qualified Biolayer Interferometry Avidity Measurements Distinguish the Heterogeneity of Antibody Interactions with Circumsporozoite Protein Antigens

scientific article published on 13 July 2018

Rapid detection of active and latent tuberculosis infection in HIV-positive individuals by enumeration of Mycobacterium tuberculosis-specific T cells

scientific article published in November 2002

Reduced Ebola vaccine responses in CMV+ young adults is associated with expansion of CD57+KLRG1+ T cells

scientific article published on 01 July 2020

Repeated tuberculin testing does not induce false positive ELISPOT results

scientific article published on February 2006

Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01B With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP.

scientific article published on 15 June 2016

Safety and Immunogenicity of Adenovirus and Poxvirus Vectored Vaccines against a Mycobacterium Avium Complex Subspecies

scientific article published on 16 March 2021

Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants

scientific article published on 25 April 2016

Safety and Immunogenicity of Malaria Vectored Vaccines Given with Routine Expanded Program on Immunization Vaccines in Gambian Infants and Neonates: A Randomized Controlled Trial

scientific article published on 20 November 2017

Safety and Immunogenicity of Novel Adenovirus Type 26- and Modified Vaccinia Ankara-Vectored Ebola Vaccines: A Randomized Clinical Trial

scientific article

Safety and Immunogenicity of a Novel Recombinant Simian Adenovirus ChAdOx2 as a Vectored Vaccine

scientific article published on 15 May 2019

Safety and Immunogenicity of the Heterosubtypic Influenza A Vaccine MVA-NP+M1 Manufactured on the AGE1.CR.pIX Avian Cell Line

scientific article published on 22 March 2019

Safety and efficacy of novel malaria vaccine regimens of RTS,S/AS01B alone, or with concomitant ChAd63-MVA-vectored vaccines expressing ME-TRAP

scientific article published on 09 October 2018

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

scientific article published on 08 December 2020

Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial

scientific article published on 18 November 2020

Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non-randomised, uncontrolled, phase 1 trial

scientific article published on 20 April 2020

Safety and immunogenicity of a heterologous prime-boost Ebola virus vaccine regimen - ChAd3-EBO-Z followed by MVA-EBO-Z in healthy adults in the UK and Senegal

scientific article published on 01 April 2019

Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Kenyan adults

scientific article

Safety and immunogenicity of heterologous prime-boost immunization with viral-vectored malaria vaccines adjuvanted with Matrix-M™.

scientific article published on 20 September 2017

Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

scientific article published on 20 July 2020

Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal.

scientific article

Screening of highly expressed mycobacterial genes identifies Rv3615c as a useful differential diagnostic antigen for the Mycobacterium tuberculosis complex

scientific article published on 2 June 2008

Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials

scientific article published in February 2021

T cell-based tracking of multidrug resistant tuberculosis infection after brief exposure

scientific article published on 6 May 2004

T-Cell-Based Diagnosis of Neonatal Multidrug-Resistant Latent Tuberculosis Infection

scientific article published on 01 January 2007

The early landscape of COVID-19 vaccine development in the UK and rest of the world

scientific article published on 27 May 2020

Translating the immunogenicity of prime-boost immunization with ChAd63 and MVA ME-TRAP from malaria naive to malaria-endemic populations

scientific article

Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species

scientific article published on January 2012

Viral Vector Malaria Vaccines Induce High-Level T Cell and Antibody Responses in West African Children and Infants

scientific article published on February 2017

Viral vectors as vaccine platforms: deployment in sight

scientific article published on 20 April 2011

Viral vectors as vaccine platforms: from immunogenicity to impact

scientific article

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