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List of works by Pedro Cravo

A primer-introduced restriction analysis-polymerase chain reaction method to detect knockdown resistance mutations in Anopheles gambiae.

scientific article published on March 2008

A systematic in silico search for target similarity identifies several approved drugs with potential activity against the Plasmodium falciparum apicoplast

scientific article

Amazonian plant natural products: perspectives for discovery of new antimalarial drug leads.

scientific article published on 02 August 2013

Analysis of genetic mutations associated with anti-malarial drug resistance in Plasmodium falciparum from the Democratic Republic of East Timor.

scientific article published on 09 April 2009

Analysis of sulphadoxine/pyrimethamine resistance-conferring mutations of Plasmodium falciparum from Mozambique reveals the absence of the dihydrofolate reductase 164L mutant

scientific article

Antimalarial drugs clear resistant parasites from partially immune hosts

scientific article

Antiplasmodial activity of lignans and extracts from Pycnanthus angolensis.

scientific article published on 31 July 2008

Artemisinin resistance in rodent malaria--mutation in the AP2 adaptor μ-chain suggests involvement of endocytosis and membrane protein trafficking

scientific article published on 5 April 2013

Chalcone Derivatives: Promising Starting Points for Drug Design.

scientific article published on 25 July 2017

Characterization of the Plasmodium falciparum sarcoplasmic/endoplasmic reticulum Ca2+-ATPase gene in samples from Equatorial Guinea before implementation of artemisinin-based combination therapy

scientific article published on 26 November 2012

Chloroquine resistance in Plasmodium chabaudi: are chloroquine-resistance transporter (crt) and multi-drug resistance (mdr1) orthologues involved?

scientific article published on January 2004

Conformation analysis of a novel fluorinated chalcone.

scientific article

Emerging Plasmodium vivax resistance to chloroquine in South America: an overview

scientific article

Epidemiological characterization of Plasmodium falciparum in the Republic of Cabo Verde: implications for potential large-scale re-emergence of malaria

scientific article

Experimental evolution of resistance to artemisinin combination therapy results in amplification of the mdr1 gene in a rodent malaria parasite

scientific article

Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites

scientific article

Failure to detect Plasmodium vivax in West and Central Africa by PCR species typing

scientific article

Gene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasites

scientific article

Genomewide scan reveals amplification of mdr1 as a common denominator of resistance to mefloquine, lumefantrine, and artemisinin in Plasmodium chabaudi malaria parasites

scientific article

Geographic structuring of the Plasmodium falciparum sarco(endo)plasmic reticulum Ca2+ ATPase (PfSERCA) gene diversity

scientific article

High frequency of the genetic polymorphisms associated with sulfadoxine-pyrimethamine resistance, among Plasmodium falciparum isolates from São Tomé and Príncipe, West Africa.

scientific article published on April 2004

How genomics is contributing to the fight against artemisinin-resistant malaria parasites

scientific article

Human lagochilascariasis-A rare helminthic disease

scientific article

Identification of genetic markers of resistance to Artemisinin Combination Therapy in the rodent model Plasmodium chabaudi.

scientific article

In Silico Chemogenomics Drug Repositioning Strategies for Neglected Tropical Diseases

scientific article published on 8 March 2018

In silico epitope mapping and experimental evaluation of the Merozoite Adhesive Erythrocytic Binding Protein (MAEBL) as a malaria vaccine candidate

scientific article published on 10 January 2018

In silico repositioning-chemogenomics strategy identifies new drugs with potential activity against multiple life stages of Schistosoma mansoni

scientific article

In silico search of energy metabolism inhibitors for alternative leishmaniasis treatments.

scientific article published on 30 March 2015

In vitro assessment of artesunate, artemether and amodiaquine susceptibility and molecular analysis of putative resistance-associated mutations of Plasmodium falciparum from São Tomé and Príncipe

scientific article published on March 2007

Is the expression of genes encoding enzymes of glutathione (GSH) metabolism involved in chloroquine resistance in Plasmodium chabaudi parasites?

scientific article published on July 2004

Is there still room to explore cyclodextrin glycosyltransferase-producers in Brazilian biodiversity?

scientific article published on 01 April 2018

MDR1-associated resistance to artesunate+mefloquine does not impair blood-stage parasite fitness in a rodent malaria model

scientific article published on 11 January 2013

Malaria parasites can develop stable resistance to artemisinin but lack mutations in candidate genes atp6 (encoding the sarcoplasmic and endoplasmic reticulum Ca2+ ATPase), tctp, mdr1, and cg10.

scientific article

Modern approaches to accelerate discovery of new antischistosomal drugs.

scientific article published on 13 April 2016

Natural products as leads in schistosome drug discovery.

scientific article

Outbreak of human malaria caused by Plasmodium simium in the Atlantic Forest in Rio de Janeiro: a molecular epidemiological investigation

scientific article

Phenotypic and genotypic profile of pyrethroid resistance in populations of the mosquito Aedes aegypti from Goiânia, Central West Brazil

scientific article

Plasmodium chabaudi: efficacy of artemisinin + curcumin combination treatment on a clone selected for artemisinin resistance in mice.

scientific article published on 7 March 2008

Plasmodium falciparum malarial parasites from Brazil lack artemisinin resistance-associated mutations in the kelch13 gene

scientific article published on 21 February 2019

Plasmodium falciparum: gene mutations and amplification of dihydrofolate reductase genes in parasites grown in vitro in presence of pyrimethamine.

scientific article published in June 2001

Plasmodium vivax in the Democratic Republic of East Timor: Parasite prevalence and antifolate resistance-associated mutations

scientific article published on 20 April 2010

QSAR-Driven Design and Discovery of Novel Compounds With Antiplasmodial and Transmission Blocking Activities.

scientific article published on 6 March 2018

Quantitative genome re-sequencing defines multiple mutations conferring chloroquine resistance in rodent malaria

scientific article

Simple and sensitive antimalarial drug screening in vitro and in vivo using transgenic luciferase expressing Plasmodium berghei parasites

scientific article published on 12 June 2008

Studies on antimalarial drug susceptibility in Colombia, in relation to Pfmdr1 and Pfcrt.

scientific article published on April 2008

Sulfadoxine-pyrimethamine resistance in Maputo, Mozambique: presence of mutations in the dhfr and dhps genes of Plasmodium falciparum

scientific article published in July 2007

The origins of African Plasmodium vivax; insights from mitochondrial genome sequencing

scientific article

Tracing the origins and signatures of selection of antifolate resistance in island populations of Plasmodium falciparum

scientific article

Validation of Pyrosequencing for accurate and high throughput estimation of allele frequencies in malaria parasites.

scientific article published on 21 December 2006

Whole genome re-sequencing identifies a mutation in an ABC transporter (mdr2) in a Plasmodium chabaudi clone with altered susceptibility to antifolate drugs ⬇️

scientific article published on September 19, 2010

pfcrt and pfmdr1 mutations and chloroquine resistance in Plasmodium falciparum from São Tomé and Príncipe, West Africa.

scientific article published on December 2002

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