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List of works by Sachel Mok

A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine

scientific article

A crucial piece in the puzzle of the artemisinin resistance mechanism in Plasmodium falciparum

scientific article

A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells

scientific article

A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria

scientific article

Adaptation of Plasmodium falciparum to its transmission environment

article

Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription

scientific article

Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival

scientific article published on 22 January 2021

Comparative transcriptional and genomic analysis of Plasmodium falciparum field isolates

scientific article published on 30 October 2009

DNA Microarray-Based Genome-Wide Analyses of Plasmodium Parasites ⬇️

scientific article published on January 1, 2013

Design of a variant surface antigen-supplemented microarray chip for whole transcriptome analysis of multiple Plasmodium falciparum cytoadherent strains, and identification of strain-transcendent rif and stevor genes

scientific article

Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

scientific article

Dynamic epigenetic regulation of gene expression during the life cycle of malaria parasite Plasmodium falciparum

scientific article

Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine

scientific article published in Nature Communications

Gene copy number variation in natural populations of Plasmodium falciparum in Eastern Africa.

scientific article

Integrated analysis of the Plasmodium species transcriptome.

scientific article published on 22 April 2016

Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance

scientific article published on 12 May 2020

New insights into the Plasmodium vivax transcriptome using RNA-Seq

scientific article published on 9 February 2016

Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites.

scientific article published on 14 March 2018

Plasmodium knowlesi gene expression differs in ex vivo compared to in vitro blood-stage cultures

scientific article

Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series

scientific article published on 20 April 2021

Quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites

scientific article published on 17 December 2008

Structural polymorphism in the promoter ofpfmrp2confersPlasmodium falciparumtolerance to quinoline drugs

scientific article (publication date: March 2014)

Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance

scientific article (publication date: April 2015)

The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background

scientific article published in Nature Communications

The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites

scholarly article

Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum

scientific article (publication date: 2010)

Transcriptional variation in the malaria parasite Plasmodium falciparum

scientific article published on 13 March 2012

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