List of works by Niraj H Tolia

A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes

scientific article published on 19 March 2021

A quantitative assay for binding and inhibition of Plasmodium falciparum Erythrocyte Binding Antigen 175 reveals high affinity binding depends on both DBL domains

scientific article published on 28 December 2013

A sugar phosphatase regulates the methylerythritol phosphate (MEP) pathway in malaria parasites

scientific article

Allosteric activation of ADAMTS13 by von Willebrand factor.

scientific article

An engineered vaccine of the Plasmodium vivax Duffy binding protein enhances induction of broadly neutralizing antibodies

scientific article published on 23 October 2017

Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi

scientific article

Argonaute slicing is required for heterochromatic silencing and spreading

scientific article

Author Correction: Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP

scientific article published on 01 November 2019

Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein

scientific article published on 18 May 2016

Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1

scientific article published on 25 August 2015

Comparison of Type 1 D-3-phosphoglycerate dehydrogenases reveals unique regulation in pathogenic Mycobacteria

scientific article published on 16 February 2015

Critical glycosylated residues in exon three of erythrocyte glycophorin A engage Plasmodium falciparum EBA-175 and define receptor specificity.

scientific article

Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion ⬇️

scientific article

DARC extracellular domain remodeling in maturating reticulocytes explains Plasmodium vivax tropism

scientific article

Data publication with the structural biology data grid supports live analysis

scientific article

Defining the interaction of the protease CpaA with its type II secretion chaperone CpaB and its contribution to virulence in Acinetobacter species

scientific article

Dimerization of Plasmodium vivax DBP is induced upon receptor binding and drives recognition of DARC

scientific article

Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.

scientific article

Exploring the "minimal" structure of a functional ADAMTS13 by mutagenesis and small-angle X-ray scattering

scientific article published on 28 January 2019

Getting in: The structural biology of malaria invasion

scientific article published on 05 September 2019

Inhibitory humoral responses to the Plasmodium falciparum vaccine candidate EBA-175 are independent of the erythrocyte invasion pathway ⬇️

scientific article published on 12 June 2013

Malaria adhesins: structure and function

scientific article published on 06 March 2014

Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption

scientific article published on December 2016

Moderately Neutralizing Epitopes in Nonfunctional Regions Dominate the Antibody Response to Plasmodium falciparum EBA-140

scientific article published on 25 March 2019

Molecular Basis for Sialic Acid-dependent Receptor Recognition by the Plasmodium falciparum Invasion Protein Erythrocyte-binding Antigen-140/BAEBL ⬇️

scientific article

Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspD

scientific article

Multimeric assembly of host-pathogen adhesion complexes involved in apicomplexan invasion ⬇️

scientific article

Native Mass Spectrometry, Ion mobility, and Collision-Induced Unfolding Categorize Malaria Antigen/Antibody Binding

scientific article

Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion.

scientific article published in October 2017

Plasmodium falciparum erythrocyte-binding antigen 175 triggers a biophysical change in the red blood cell that facilitates invasion ⬇️

scientific article (publication date: 18 April 2017)

Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion ⬇️

scientific article (publication date: 22 February 2017)

Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes

scientific article published on 8 May 2017

Prediction of New Stabilizing Mutations Based on Mechanistic Insights from Markov State Models

scientific article published on 21 November 2017

Purified Argonaute2 and an siRNA form recombinant human RISC

scientific article (publication date: April 2005)

Red blood cell invasion by Plasmodium vivax: structural basis for DBP engagement of DARC ⬇️

scientific article published in January 2014

Red cell receptors as access points for malaria infection

scientific article

Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii

scientific article published on 20 August 2015

Semisynthetic Analogues of Anhydrotetracycline as Inhibitors of Tetracycline Destructase Enzymes

scientific article published on 05 March 2019

Shed EBA-175 mediates red blood cell clustering that enhances malaria parasite growth and enables immune evasion

scientific article published on 17 December 2018

Slicer and the argonautes

scientific article published on January 2007

Strategies for protein coexpression in Escherichia coli

scientific article published in January 2006

Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum

scholarly article by Niraj H Tolia et al published August 2005 in Cell

Structural analysis of the synthetic Duffy Binding Protein (DBP) antigen DEKnull relevant for Plasmodium vivax malaria vaccine design

scientific article

Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175 ⬇️

scientific article

Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP

scientific article published on 27 May 2019

Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA

scientific article published on 15 January 2021

Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparum

scientific article published in July 2005

Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance

scientific article published on 15 May 2020

The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

scientific article

The structure of Acinetobacter-secreted protease CpaA complexed with its chaperone CpaB reveals a novel mode of a T2SS chaperone-substrate interaction

scientific article published on 18 July 2019

Paulina is supported by:

About Paulina

Help