List of works - Michelle J Boyle

A Novel Model of Asymptomatic Plasmodium Parasitemia That Recapitulates Elements of the Human Immune Response to Chronic Infection

scientific article

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation

scientific article

A phase 1 trial of MSP2-C1, a blood-stage malaria vaccine containing 2 isoforms of MSP2 formulated with Montanide® ISA 720

scientific article (publication date: 2011)

Age-dependent changes in circulating Tfh cells influence development of functional malaria antibodies in children

scientific article published in 2022

Antibody Targets on the Surface of Plasmodium falciparum-Infected Erythrocytes That Are Associated With Immunity to Severe Malaria in Young Children

scientific article published on 01 February 2019

Antigenic characterization of an intrinsically unstructured protein, Plasmodium falciparum merozoite surface protein 2.

scientific article

Challenges and strategies for developing efficacious and long-lasting malaria vaccines

scientific article published on 01 January 2019

Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria

scientific article published on 16 July 2015

Dichotomous miR expression and immune responses following primary blood-stage malaria

scientific article

Effective Antimalarial Chemoprevention in Childhood Enhances the Quality of CD4+ T Cells and Limits Their Production of Immunoregulatory Interleukin 10.

scientific article published on 10 April 2016

Effector Phenotype of Plasmodium falciparum-Specific CD4+ T Cells Is Influenced by Both Age and Transmission Intensity in Naturally Exposed Populations

scientific article

Effects of Aging on Parasite Biomass, Inflammation, Endothelial Activation, Microvascular Dysfunction and Disease Severity in Plasmodium knowlesi and Plasmodium falciparum Malaria

scientific article

Evaluating Complement-Mediated Humoral Immunity to P. falciparum Blood Stages.

scientific article published on 19 November 2016

FCRL5 Delineates Functionally Impaired Memory B Cells Associated with Plasmodium falciparum Exposure

scientific article published on 19 May 2015

Frequent Malaria Drives Progressive Vδ2 T-Cell Loss, Dysfunction, and CD16 Up-regulation During Early Childhood

scientific article published on 13 December 2015

Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malaria ⬇️

scientific article

Human immunization with a polymorphic malaria vaccine candidate induced antibodies to conserved epitopes that promote functional antibodies to multiple parasite strains.

scientific article

Identification of Heparin Modifications and Polysaccharide Inhibitors of Plasmodium falciparum Merozoite Invasion That Have Potential for Novel Drug Development ⬇️

scientific article published on 11 September 2017

IgM in human immunity to Plasmodium falciparum malaria

scientific article published on 25 September 2019

Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria

scientific article published on 18 May 2020

Interactions with heparin-like molecules during erythrocyte invasion by Plasmodium falciparum merozoites

scientific article published on 10 March 2010

Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development ⬇️

scientific article

Loss of complement regulatory proteins on red blood cells in mild malarial anaemia and in Plasmodium falciparum induced blood-stage infection

scientific article published on 18 September 2019

Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia

scientific article published on 15 November 2018

Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria

scientific article

New approaches to studying Plasmodium falciparum merozoite invasion and insights into invasion biology

scientific article published on 05 December 2012

Novel Bcl-2 homology-3 domain-like sequences identified from screening randomized peptide libraries for inhibitors of the pro-survival Bcl-2 proteins.

scientific article published on 10 September 2009

Opsonic phagocytosis of Plasmodium falciparum merozoites: mechanism in human immunity and a correlate of protection against malaria

scientific article

Plasmodium falciparum Activates CD16+ Dendritic Cells to Produce Tumor Necrosis Factor and Interleukin-10 in Subpatent Malaria.

scientific article published in January 2019

Quantifying Heterogeneous Malaria Exposure and Clinical Protection in a Cohort of Ugandan Children

scientific article published on August 2016

Recent insights into humoral immunity targeting Plasmodium falciparum and Plasmodium vivax malaria

scientific article

Reduced risk of placental parasitemia associated with complement fixation on Plasmodium falciparum by antibodies among pregnant women

scientific article published on 24 August 2021

Reticulocyte-binding protein homologue 5 - an essential adhesin involved in invasion of human erythrocytes by Plasmodium falciparum

scientific article published on 25 October 2008

Sequential processing of merozoite surface proteins during and after erythrocyte invasion by Plasmodium falciparum ⬇️

scientific article

Structural basis for binding of Plasmodium falciparum erythrocyte membrane protein 1 to chondroitin sulfate and placental tissue and the influence of protein polymorphisms on binding specificity

scientific article published on 11 June 2007

Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte

scientific article published in January 2011

Targeting malaria parasite invasion of red blood cells as an antimalarial strategy

scientific article published on 01 May 2019

Targets of complement-fixing antibodies in protective immunity against malaria in children

scientific article published in Nature Communications

The Development of Plasmodium falciparum-Specific IL10 CD4 T Cells and Protection from Malaria in Children in an Area of High Malaria Transmission

scientific article published on 19 October 2017

Transcriptional profiling and immunophenotyping show sustained activation of blood monocytes in subpatent Plasmodium falciparum infection

scientific article published on 18 June 2020

Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure

scientific article published on 13 September 2017

List of works by Michelle J Boyle

A Novel Model of Asymptomatic Plasmodium Parasitemia That Recapitulates Elements of the Human Immune Response to Chronic Infection

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation

A phase 1 trial of MSP2-C1, a blood-stage malaria vaccine containing 2 isoforms of MSP2 formulated with Montanide® ISA 720

Age-dependent changes in circulating Tfh cells influence development of functional malaria antibodies in children

Antibody Targets on the Surface of Plasmodium falciparum-Infected Erythrocytes That Are Associated With Immunity to Severe Malaria in Young Children

Antigenic characterization of an intrinsically unstructured protein, Plasmodium falciparum merozoite surface protein 2.

Challenges and strategies for developing efficacious and long-lasting malaria vaccines

Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria

Dichotomous miR expression and immune responses following primary blood-stage malaria

Effective Antimalarial Chemoprevention in Childhood Enhances the Quality of CD4+ T Cells and Limits Their Production of Immunoregulatory Interleukin 10.

Effector Phenotype of Plasmodium falciparum-Specific CD4+ T Cells Is Influenced by Both Age and Transmission Intensity in Naturally Exposed Populations

Effects of Aging on Parasite Biomass, Inflammation, Endothelial Activation, Microvascular Dysfunction and Disease Severity in Plasmodium knowlesi and Plasmodium falciparum Malaria

Evaluating Complement-Mediated Humoral Immunity to P. falciparum Blood Stages.

FCRL5 Delineates Functionally Impaired Memory B Cells Associated with Plasmodium falciparum Exposure

Frequent Malaria Drives Progressive Vδ2 T-Cell Loss, Dysfunction, and CD16 Up-regulation During Early Childhood

Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malaria ⬇️

Human immunization with a polymorphic malaria vaccine candidate induced antibodies to conserved epitopes that promote functional antibodies to multiple parasite strains.

Identification of Heparin Modifications and Polysaccharide Inhibitors of Plasmodium falciparum Merozoite Invasion That Have Potential for Novel Drug Development ⬇️

IgM in human immunity to Plasmodium falciparum malaria

Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria

Interactions with heparin-like molecules during erythrocyte invasion by Plasmodium falciparum merozoites

Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development ⬇️

Loss of complement regulatory proteins on red blood cells in mild malarial anaemia and in Plasmodium falciparum induced blood-stage infection

Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia

Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria

New approaches to studying Plasmodium falciparum merozoite invasion and insights into invasion biology

Novel Bcl-2 homology-3 domain-like sequences identified from screening randomized peptide libraries for inhibitors of the pro-survival Bcl-2 proteins.

Opsonic phagocytosis of Plasmodium falciparum merozoites: mechanism in human immunity and a correlate of protection against malaria

Plasmodium falciparum Activates CD16+ Dendritic Cells to Produce Tumor Necrosis Factor and Interleukin-10 in Subpatent Malaria.

Quantifying Heterogeneous Malaria Exposure and Clinical Protection in a Cohort of Ugandan Children

Recent insights into humoral immunity targeting Plasmodium falciparum and Plasmodium vivax malaria

Reduced risk of placental parasitemia associated with complement fixation on Plasmodium falciparum by antibodies among pregnant women

Reticulocyte-binding protein homologue 5 - an essential adhesin involved in invasion of human erythrocytes by Plasmodium falciparum

Sequential processing of merozoite surface proteins during and after erythrocyte invasion by Plasmodium falciparum ⬇️

Structural basis for binding of Plasmodium falciparum erythrocyte membrane protein 1 to chondroitin sulfate and placental tissue and the influence of protein polymorphisms on binding specificity

Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte

Targeting malaria parasite invasion of red blood cells as an antimalarial strategy

Targets of complement-fixing antibodies in protective immunity against malaria in children

The Development of Plasmodium falciparum-Specific IL10 CD4 T Cells and Protection from Malaria in Children in an Area of High Malaria Transmission

Transcriptional profiling and immunophenotyping show sustained activation of blood monocytes in subpatent Plasmodium falciparum infection

Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure