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List of works by Lars Hviid

A longitudinal study of type-specific antibody responses to Plasmodium falciparum merozoite surface protein-1 in an area of unstable malaria in Sudan.

scientific article published in July 1998

A new portable device for automatic controlled-gradient cryopreservation of blood mononuclear cells

scientific article published in January 1993

A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies

scientific article published on 3 December 2012

A sub-family of common and highly conserved Plasmodium falciparum var genes.

scientific article

A vaccine targeted specifically to prevent cerebral malaria - is there hope?

scholarly article by Lars Hviid et al published July 2018 in Expert Review of Vaccines

Acquisition and decay of antibodies to pregnancy-associated variant antigens on the surface of Plasmodium falciparum-infected erythrocytes that protect against placental parasitemia.

scientific article published on 9 August 2001

Acquisition of IGG to ICAM-1-Binding DBLΒ Domains in the plasmodium falciparum erythrocyte membrane protein 1 antigen family varies between groups A, B, and C

scientific article published on 19 September 2019

Acute P. falciparum malaria induces a loss of CD28- T IFN-gamma producing cells

scientific article

Adhesion specificities of Plasmodium falciparum-infected erythrocytes involved in the pathogenesis of pregnancy-associated malaria

scientific article published in June 2007

Aligned hemozoin crystals in curved clusters in malarial red blood cells revealed by nanoprobe X-ray Fe fluorescence and diffraction

scientific article published on 25 June 2012

Alkamides fromPhyllanthus fraternus ⬇️

scientific article published on March 1, 1998

Analysis of IgG with specificity for variant surface antigens expressed by placental Plasmodium falciparum isolates

scientific article

Antibodies to the N-terminal block 2 of plasmodium falciparum merozoite surface protein 1 are associated with protection against clinical malaria ⬇️

scientific article published in November 2004

Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children.

scholarly article

Antibody responses to Rhoptry-Associated Protein-1 (RAP-1) of Plasmodium falciparum parasites in humans from areas of different malaria endemicity.

scientific article published on September 1997

B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites

scientific article published on 24 February 2014

Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes

scientific article

Biochemical characterization, localization and immunostimulating properties of a soluble glycoprotein, Ag1, isolated from in vitro cultures of Plasmodium falciparum

scientific article published in January 1990

Blood outgrowth endothelial cells (BOECs) as a novel tool for studying adhesion of Plasmodium falciparum-infected erythrocytes

scientific article published in PLoS ONE

CCR3 Expression Induced by IL-2 and IL-4 Functioning as a Death Receptor for B Cells

scientific article published on 5 August 2003

CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression

scientific article

Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1-based vaccines to prevent it

scientific article published on 27 September 2019

Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites

scientific article published on 12 June 2007

Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants

scientific article published on 15 November 2010

Complement binding to erythrocytes is associated with macrophage activation and reduced haemoglobin in Plasmodium falciparum malaria

scientific article published in September 2001

Comprehensive analysis of Fc-mediated IgM binding to the Plasmodium falciparum erythrocyte membrane protein 1 family in three parasite clones

scientific article published on 15 April 2019

Cytokine production and apoptosis among T cells from patients under treatment for Plasmodium falciparum malaria

scientific article published in January 2002

Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria

scientific article

Danish malaria research from the frail beginning to internationally acknowledged research ⬇️

scientific article published in May 2017

Detection of antibodies to variant antigens on Plasmodium falciparum-infected erythrocytes by flow cytometry

scientific article published on 01 April 1999

Detection of very low level Plasmodium falciparum infections using the nested polymerase chain reaction and a reassessment of the epidemiology of unstable malaria in Sudan.

scientific article published in April 1996

Developing Plasmodium falciparum malaria vaccines for populations living in areas with stable parasite transmission

article

Development of vaccines against Plasmodium falciparum malaria: taking lessons from naturally acquired protective immunity

scientific article published on 21 February 2007

Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania

scientific article published on 4 February 2008

Differential T-cell expression of LFA-1 in residents from Africa and Denmark. Description of the phenomenon and its possible basis.

scientific article published in February 1994

Differential induction of immunoglobulin G to Plasmodium falciparum variant surface antigens during the transmission season in Daraweesh, Sudan

scientific article published on 27 June 2005

Effects of pregnancy and intensity of Plasmodium falciparum transmission on immunoglobulin G subclass responses to variant surface antigens

scientific article

Elevated levels of nitric oxide and low levels of haptoglobin are associated with severe malarial anaemia in African children

scientific article published in August 2002

Endemic Burkitt lymphoma – an aggressive childhood cancer linked to Plasmodium falciparum exposure, but not to exposure to other malaria parasites

scientific article published on 04 March 2020

Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration

scientific article

Evasion of Classical Complement Pathway Activation on -Infected Erythrocytes Opsonized by PfEMP1-Specific IgG

scientific article published in 2018

Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1

scientific article

Evidence for the involvement of VAR2CSA in pregnancy-associated malaria

scientific article

Evidence of Endothelial Inflammation, T Cell Activation, and T Cell Reallocation in Uncomplicated Plasmodium Falciparum Malaria

scientific article published on September 1, 1994

Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans

scientific article

Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection

scientific article

Functional Antibodies against Placental Malaria Parasites Are Variant Dependent and Differ by Geographic Region

scientific article published on 20 June 2019

Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigens

scientific article

Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children

scientific article

High frequency of circulating gamma delta T cells with dominance of the v(delta)1 subset in a healthy population.

scientific article published in June 2000

Human T-cell recognition of synthetic peptides representing conserved and variant sequences from the merozoite surface protein 2 of Plasmodium falciparum ⬇️

scientific article published on June 1, 1997

Human Vδ1 T Cells in the Immune Response to Infection

scientific article published on 14 February 2019

Human monoclonal IgG selection of Plasmodium falciparum for the expression of placental malaria-specific variant surface antigens

scientific article published in June 2009

Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA

scientific article published on 14 December 2006

IgG Responses to the Plasmodium falciparum Antigen VAR2CSA in Colombia Are Restricted to Pregnancy and Are Not Induced by Exposure to Plasmodium vivax

article

Immune selection and within-host competition can structure the repertoire of variant surface antigens in Plasmodium falciparum--a mathematical model

scientific article

Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria

scientific article published on 5 February 2007

Immunoglobulin M: Restrainer of Inflammation and Mediator of Immune Evasion by Plasmodium falciparum Malaria

scientific article published on 17 November 2015

In vitro Plasmodium falciparum drug sensitivity assay: inhibition of parasite growth by incorporation of stomatocytogenic amphiphiles into the erythrocyte membrane

scientific article published in May 2002

In vitro selection for adhesion of Plasmodium falciparum-infected erythrocytes to ABO antigens does not affect PfEMP1 and RIFIN expression

scientific article published on 30 July 2020

In vitro selection of Plasmodium falciparum 3D7 for expression of variant surface antigens associated with severe malaria in African children

scientific article published in August 2003

In vivo switching between variant surface antigens in human Plasmodium falciparum infection.

scientific article published on 5 August 2002

Increased Plasmodium chabaudi malaria mortality in mice with nutritional iron deficiency can be reduced by short-term adjunctive iron supplementation.

scientific article published on 16 January 2018

Increased eosinophil activity in acute plasmodium falciparum infection - association with cerebral malaria

scientific article published in May 1998

Increased levels of soluble CD30 in plasma of patients with Plasmodium falciparum malaria

scientific article published on May 2002

Increased plasma levels of soluble ICAM-1 and ELAM-1 (E-selectin) during acute Plasmodium falciparum malaria.

scientific article published in April 1993

Increased plasma levels of soluble IL-2R are associated with severe Plasmodium falciparum malaria.

scientific article published in April 1994

Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites

scientific article (publication date: July 2014)

Insecticide-Treated Bed Nets Reduce Plasma Antibody Levels and Limit the Repertoire of Antibodies to Plasmodium falciparum Variant Surface Antigens ⬇️

scientific article published on November 1, 2001

Insights into deregulated TNF and IL-10 production in malaria: Implications for understanding severe malarial anaemia

scientific article

Interferon-gamma Production by Human T Cells and Natural Killer Cells In Vitro in Response to Antigens from the Two Intracellular Pathogens Mycobacterium tuberculosis and Leishmania major

article

Interferon-γ- and Tumour Necrosis Factor-α-Producing Cells in Humans who are Immune to Cutaneous Leishmaniasis

article

Intermittent preventive sulfadoxine-pyrimethamine treatment of primigravidae reduces levels of plasma immunoglobulin G, which protects against pregnancy-associated Plasmodium falciparum malaria

scientific article published on September 2004

Investigating the function of Fc-specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting

scientific article

Kinetics of B cell responses to plasmodium falciparum erythrocyte membrane protein 1 in ghanaian women naturally exposed to malaria parasites

research work

Kinetics of antibody responses to pfrh5-complex antigens in ghanaian children with plasmodium falciparum malaria

scientific article published on 8 June 2018

Kinetics of human T-cell expression of LFA-1, IL-2 receptor, and ICAM-1 following antigenic stimulation in vitro.

scientific article published in January 1993

Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria

scientific article

Late recrudescence of Plasmodium falciparum malaria in pregnancy

scientific article published on 24 April 2006

Leishmania-specific T cells expressing interferon-gamma (IFN-gamma) and IL-10 upon activation are expanded in individuals cured of visceral leishmaniasis

scientific article published on 01 June 1999

Levels of antibody to conserved parts of Plasmodium falciparum merozoite surface protein 1 in Ghanaian children are not associated with protection from clinical malaria.

scientific article

Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodes

scientific article published in May 2006

Licochalcone A, a new antimalarial agent, inhibits in vitro growth of the human malaria parasite Plasmodium falciparum and protects mice from P. yoelii infection

scientific article

Looking for Needles in the Plasmodial Haystack

scientific article published on 27 March 2019

Loss of cellular immune reactivity during acutePlasmodium falciparummalaria

article

Low plasma concentrations of interleukin-10 in severe malarial anaemia compared with cerebral and uncomplicated malaria.

scientific article published in June 1998

Lymphoproliferative Responses to Plasmodium falciparum Antigens in Children With and Without the Sickle Cell Trait ⬇️

scientific article published on August 1, 1991

Malaria causes long-term effects on markers of iron status in children: a critical assessment of existing clinical and epidemiological tools

scientific article published on 11 December 2018

Malaria immunity in infants: a special case of a general phenomenon?

scientific article published on February 2004

Malaria in pregnancy: pathogenesis and immunity

scientific article published on February 2007

Malaria parasite evasion of classical complement pathway attack

scientific article published in September 2017

Malaria vaccines: immunity, models and monoclonal antibodies

scientific article published on 31 July 2008

Malaria-induced acquisition of antibodies to plasmodium falciparum variant surface antigens

scientific article published on June 2002

Mannose-binding lectin is a disease modifier in clinical malaria and may function as opsonin for Plasmodium falciparum-infected erythrocytes

scientific article published on September 2003

Maternal vitamin A supplementation and immunity to malaria in pregnancy in Ghanaian primigravids

scientific article published on December 2005

Maternally transmitted antibodies to pregnancy-associated variant antigens on the surface of erythrocytes infected with Plasmodium falciparum: relation to child susceptibility to malaria

scientific article published on February 2003

Measuring Naturally Acquired Phagocytosis-Inducing Antibodies to Plasmodium falciparum Parasites by a Flow Cytometry-Based Assay

scientific article published on 06 August 2020

Modeling malaria infection and immunity against variant surface antigens in Príncipe Island, West Africa.

scientific article

Modulation of the cellular immune response during Plasmodium falciparum infections in sickle cell trait individuals

scientific article published in April 1992

Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 Variants per Genome Can Bind IgM via Its Fc Fragment Fcμ

scientific article

Natural and vaccine-induced acquisition of cross-reactive IgG inhibiting ICAM-1-specific binding of a PfEMP1 subtype associated specifically with cerebral malaria

scientific article published on 5 February 2018

Naturally acquired immunity to Plasmodium falciparum malaria in Africa

scientific article

Novel Plasmodium falciparum malaria vaccines: evidence-based searching for variant surface antigens as candidates for vaccination against pregnancy-associated malaria

scientific article

Of mice and women: rodent models of placental malaria

scientific article published on 31 May 2010

Peripheral T-cell non-responsiveness in individuals exposed to Plasmodium falciparum malaria.

scientific article published on January 1995

Perturbation and proinflammatory type activation of V delta 1(+) gamma delta T cells in African children with Plasmodium falciparum malaria

scientific article published on May 2001

PfEMP1 - A Parasite Protein Family of Key Importance in Plasmodium falciparum Malaria Immunity and Pathogenesis

scientific article published on 23 March 2015

PfEMP1-Specific Immunoglobulin G Reactivity Among Beninese Pregnant Women With Sickle Cell Trait

scientific article published on 15 November 2021

Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes

scientific article

Plasmodium falciparum expressing domain cassette 5 type PfEMP1 (DC5-PfEMP1) bind PECAM1.

scientific article

Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo

scientific article

Plasmodium falciparum variant surface antigen expression varies between isolates causing severe and nonsevere malaria and is modified by acquired immunity

scientific article published in April 2002

Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed

scientific article

Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin

scientific article published on 14 March 2007

Pregnancy-Associated Malaria in a Rural Community of Ghana

scientific article published on March 2009

Pregnancy-associated malaria

scientific article published on April 2006

Rapid acquisition of isolate-specific antibodies to chondroitin sulfate A-adherent plasmodium falciparum isolates in Ghanaian primigravidae

scientific article published in May 2005

Rapid reemergence of T cells into peripheral circulation following treatment of severe and uncomplicated plasmodium falciparum malaria.

scientific article

Recombinant human tumour necrosis factor is not inhibitory to Plasmodium falciparum in vitro

Reliable cell and tissue morphology-based diagnosis of endemic Burkitt lymphoma in resource-constrained settings in Ghana

scientific article published on 30 December 2019

Rifins, rosetting, and red blood cells

scientific article

Seasonal changes in cell mediated immune responses to soluble Plasmodium falciparum antigens in children with haemoglobin AA and haemoglobin AS.

scientific article published in January 1992

Seasonal changes in the Plasmodium falciparum population in individuals and their relationship to clinical malaria: a longitudinal study in a Sudanese village.

scientific article

Seasonal variation in agglutination of Plasmodium falciparum-infected erythrocytes ⬇️

scientific article published on April 1, 1998

Selective activation of TCR-gammadelta+ cells in endemic Burkitt's lymphoma

scientific article published on 23 May 2007

Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria

scientific article (publication date: 30 May 2003)

Specificity and cross-reactivity of Plasmodium falciparum variant surface antigen-specific antibody responses

scientific article published on April 2003

Structure-Activity Studies:In vitroAntileishmanial and Antimalarial Activities of Anthraquinones fromMorinda lucida

Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria

scientific article published on March 2017

The Density of Knobs on Plasmodium falciparum-Infected Erythrocytes Depends on Developmental Age and Varies among Isolates

scientific article

The Etiology of Placental Plasmodium Falciparum Malaria in African Women

scientific article published on 22 March 2018

The case for PfEMP1-based vaccines to protect pregnant women against Plasmodium falciparum malaria ⬇️

scientific article published on October 1, 2011

The concentration of the C-type lectin, mannan-binding protein, in human plasma increases during an acute phase response.

scientific article published on October 1992

The epidemiology of febrile malaria episodes in an area of unstable and seasonal transmission

scientific article published on November 2000

The gamma/delta T-cell response to Plasmodium falciparum malaria in a population in which malaria is endemic.

scientific article

The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs

scientific article

The major surface glycoprotein (gp63) from Leishmania major and Leishmania donovani cleaves CD4 molecules on human T cells.

scientific article published in May 1994

The role of Plasmodium falciparum variant surface antigens in protective immunity and vaccine development.

scientific article published on 23 January 2010

Transfected HEK293 cells expressing functional recombinant intercellular adhesion molecule 1 (ICAM-1)--a receptor associated with severe Plasmodium falciparum malaria

scientific article

Transient depletion of T cells with high LFA-1 expression from peripheral circulation during acute Plasmodium falciparum malaria.

scientific article published in May 1991

Trying to remember: immunological B cell memory to malaria

scientific article

Unraveling the impact of malaria exposure before birth

scientific article published on 28 July 2009

V beta profiles in African children with acute cerebral or uncomplicated malaria: very focused changes among a remarkable global stability

scientific article

VAR2CSA and protective immunity against pregnancy-associated Plasmodium falciparum malaria.

scientific article

VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes

scientific article

Variant surface antigen-specific IgG and protection against clinical consequences of pregnancy-associated Plasmodium falciparum malaria

scientific article published in January 2004

Variant surface antigens, virulence genes and the pathogenesis of malaria

scientific article published in December 2004

Variant-specific immunity to Plasmodium berghei in pregnant mice

scientific article published on 23 February 2009

West African donors have high percentages of activated cytokine producing T cells that are prone to apoptosis

scientific article published in October 2001

What is the cause of lymphopenia in malaria?

scientific article published on October 2000

[A worm in the toilet] ⬇️

α2-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized Erythrocytes

scientific article published on 2 July 2015

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