List of works by Ali Salanti

A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA.

scientific article published on 23 November 2015

A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in Plasmodium falciparum infected erythrocytes

scientific article

A proof-of-concept study for the design of a VLP-based combinatorial HPV and placental malaria vaccine

scholarly article by Christoph M Janitzek et al published 27 March 2019 in Scientific Reports

A sub-family of common and highly conserved Plasmodium falciparum var genes.

scientific article

A versatile, high through-put, bead-based phagocytosis assay for Plasmodium falciparum

scientific article published on 31 October 2017

Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria

scientific article published on 26 May 2016

An Oncofetal Glycosaminoglycan Modification Provides Therapeutic Access to Cisplatin-resistant Bladder Cancer

scientific article published on 10 April 2017

An upstream open reading frame controls translation of var2csa, a gene implicated in placental malaria

scientific article

Analysis of antibodies to newly described Plasmodium falciparum merozoite antigens supports MSPDBL2 as a predicted target of naturally acquired immunity

scientific article published on 29 July 2013

Antibodies to Cryptic Epitopes in Distant Homologues Underpin a Mechanism of Heterologous Immunity between Plasmodium vivax PvDBP and Plasmodium falciparum VAR2CSA

scientific article published on 08 October 2019

Antibody responses to the full-length VAR2CSA and its DBL domains in Cameroonian children and teenagers

scientific article

Association of Antibodies to VAR2CSA and Merozoite Antigens with Pregnancy Outcomes in Women Living in Yaoundé, Cameroon

scientific article published on 22 August 2018

Atovaquone/proguanil resistance in Africa: a case report.

scientific article

Bacterial superglue enables easy development of efficient virus-like particle based vaccines

scientific article

Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses

scientific article

Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes

scientific article

Burkitt lymphoma expresses oncofetal chondroitin sulfate without being a reservoir for placental malaria sequestration

scientific article published on 20 December 2016

Can any lessons be learned from the ambiguous glycan binding of PfEMP1 domains?

scientific article published on 26 February 2010

Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

scientific article published on 12 January 2021

Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites

scientific article published on 12 June 2007

Characterization of human placental glycosaminoglycans and regional binding to VAR2CSA in malaria infected erythrocytes

scientific article published on 25 October 2013

Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants

scientific article published on 15 November 2010

Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 expressed by CSA-binding parasites

scientific article published on 24 March 2009

Clinical Outcomes of Submicroscopic Infections and Correlates of Protection of VAR2CSA Antibodies in a Longitudinal Study of Pregnant Women in Colombia

scientific article published on 29 January 2018

Clinical development of a VAR2CSA-based placental malaria vaccine PAMVAC: Quantifying vaccine antigen-specific memory B & T cell activity in Beninese primigravidae

scientific article published on 17 May 2017

Comparison of functional assays used in the clinical development of a placental malaria vaccine

scientific article published on 21 December 2016

Comparison of the specificity of antibodies to VAR2CSA in Cameroonian multigravidae with and without placental malaria: a retrospective case-control study

scientific article

Cross-Species Immune Recognition Between Plasmodium vivax Duffy Binding Protein Antibodies and the Plasmodium falciparum Surface Antigen VAR2CSA

scientific article published in 2019

Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding

scientific article published on 19 May 2021

Cytoadhesion of Plasmodium falciparum-infected erythrocytes to chondroitin-4-sulfate is cooperative and shear enhanced

scientific article

DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families

scientific article

Different mutation patterns of atovaquone resistance to Plasmodium falciparum in vitro and in vivo: rapid detection of codon 268 polymorphisms in the cytochrome b as potential in vivo resistance marker

scientific article

Differential adhesion-inhibitory patterns of antibodies raised against two major variants of the NTS-DBL2X region of VAR2CSA.

scientific article

Differential evolution of anti-VAR2CSA- IgG3 in primigravidae and multigravidae pregnant women infected by Plasmodium falciparum

scientific article

Differential induction of functional IgG using the Plasmodium falciparum placental malaria vaccine candidate VAR2CSA

scientific article

Dual stage synthesis and crucial role of cytoadherence-linked asexual gene 9 in the surface expression of malaria parasite var proteins

scientific article

Dynamics of anti-VAR2CSA immunoglobulin G response in a cohort of senegalese pregnant women.

scientific article published on 30 January 2006

Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration

scientific article

Evidence for globally shared, cross-reacting polymorphic epitopes in the pregnancy-associated malaria vaccine candidate VAR2CSA.

scientific article published on 4 February 2008

Evidence for the involvement of VAR2CSA in pregnancy-associated malaria

scientific article

Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans

scientific article

Fighting Cancer Using an Oncofetal Glycosaminoglycan-Binding Protein from Malaria Parasites

scientific article published on 11 December 2018

First-in-human, Randomized, Double-blind Clinical Trial of Differentially Adjuvanted PAMVAC, A Vaccine Candidate to Prevent Pregnancy-associated Malaria

scientific article published on 01 October 2019

Full-length recombinant Plasmodium falciparum VAR2CSA binds specifically to CSPG and induces potent parasite adhesion-blocking antibodies

scientific article

High avidity antibodies to full-length VAR2CSA correlate with absence of placental malaria ⬇️

scientific article

High efficacy of anti DBL4ɛ-VAR2CSA antibodies in inhibition of CSA-binding Plasmodium falciparum-infected erythrocytes from pregnant women

scientific article

High level of var2csa transcription by Plasmodium falciparum isolated from the placenta

scientific article

High levels of antibodies to multiple domains and strains of VAR2CSA correlate with the absence of placental malaria in Cameroonian women living in an area of high Plasmodium falciparum transmission

scientific article published on 13 February 2012

High-Throughput Testing of Antibody-Dependent Binding Inhibition of Placental Malaria Parasites

scientific article published on January 2015

Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA

scientific article published on 14 December 2006

Identification and characterization of B-cell epitopes in the DBL4ε domain of VAR2CSA

scientific article

Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA.

scientific article published on 22 September 2015

Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA

scientific article

IgM, Fc mu Rs, and malarial immune evasion

scientific article

Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display

scientific article published on 31 May 2017

Induction of adhesion-inhibitory antibodies against placental Plasmodium falciparum parasites by using single domains of VAR2CSA.

scientific article published on 23 March 2009

Infections with Plasmodium falciparum during pregnancy affect VAR2CSA DBL-5 domain-specific T cell cytokine responses

scientific article published on 21 September 2016

Influence of Intermittent Preventive Treatment on Antibodies to VAR2CSA in Pregnant Cameroonian Women

scientific article published on 28 December 2015

Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells

scientific article published on 23 February 2022

Island-wide diversity in single nucleotide polymorphisms of the Plasmodium vivax dihydrofolate reductase and dihydropteroate synthetase genes in Sri Lanka.

scientific article published on 9 March 2007

Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria

scientific article

Limited cross-reactivity among domains of the Plasmodium falciparum clone 3D7 erythrocyte membrane protein 1 family

scientific article

Molecular cloning of a K(+) channel from the malaria parasite Plasmodium falciparum

scientific article

Molecular dissection of placental malaria protein VAR2CSA interaction with a chemo-enzymatically synthesized chondroitin sulfate library

scientific article

Multilaboratory approach to preclinical evaluation of vaccine immunogens for placental malaria

scientific article published on 3 December 2012

Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates

scientific article

Novel adenovirus encoded virus-like particles displaying the placental malaria associated VAR2CSA antigen

scientific article published on 25 January 2017

Oncofetal Chondroitin Sulfate Glycosaminoglycans Are Key Players in Integrin Signaling and Tumor Cell Motility.

scientific article published on 21 September 2016

Persistent Plasmodium falciparum Infection in Women With an Intent to Become Pregnant as a Risk Factor for Pregnancy-associated Malaria

scientific article published on 4 May 2018

Pfs230 and Pfs48/45 Fusion Proteins Elicit Strong Transmission-Blocking Antibody Responses Against Plasmodium falciparum.

scientific article

Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1

scientific article (publication date: August 2016)

Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes

scientific article

Plasmodium falciparum infection early in pregnancy has profound consequences for foetal growth

scientific article published on 6 October 2017

Plasmodium falciparum mutant haplotype infection during pregnancy associated with reduced birthweight, Tanzania

scientific article published on January 2013

Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression

scientific article

Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin

scientific article published on 14 March 2007

Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women

scientific article

Pre-clinical and clinical development of the first placental malaria vaccine

scientific article

Protective Antibodies against Placental Malaria and Poor Outcomes during Pregnancy, Benin

scientific article published on May 2015

Rainbow trout (Oncorhynchus mykiss) immune response towards a recombinant vaccine targeting the parasitic ciliate Ichthyophthirius multifiliis

scientific article published on 26 May 2017

Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting.

scientific article

Reliability of rapid diagnostic tests in diagnosing pregnancy-associated malaria in north-eastern Tanzania.

scientific article

Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria

scientific article (publication date: 30 May 2003)

Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains

scientific article published on 12 August 2009

Several domains from VAR2CSA can induce Plasmodium falciparum adhesion-blocking antibodies

scientific article

Statistical prediction of immunity to placental malaria based on multi-assay antibody data for malarial antigens

scientific article published on 29 September 2017

Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria.

scientific article

Structural insight into epitopes in the pregnancy-associated malaria protein VAR2CSA

scientific article

Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regions

scientific article

Targeted disruption of a ring-infected erythrocyte surface antigen (RESA)-like export protein gene in Plasmodium falciparum confers stable chondroitin 4-sulfate cytoadherence capacity

scientific article (publication date: 5 December 2014)

Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein

scientific article published on October 2015

The GAGOme: a cell-based library of displayed glycosaminoglycans

scientific article published on 13 August 2018

The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine

scientific article

The NTS-DBL2X region of VAR2CSA induces cross-reactive antibodies that inhibit adhesion of several Plasmodium falciparum isolates to chondroitin sulfate A.

scientific article published in October 2011

The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner

scientific article published in Nature Communications

The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site

research work

The chondroitin sulfate A-binding site of the VAR2CSA protein involves multiple N-terminal domains

scientific article

The effect of adjuvants on the immune response induced by a DBL4ɛ-ID4 VAR2CSA based Plasmodium falciparum vaccine against placental malaria.

scientific article published on 26 November 2011

The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs

scientific article

The specificity of the malarial VAR2CSA protein for chondroitin sulfate depends on 4-O-sulfation and ligand accessibility

scientific article published on 08 November 2021

Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA.

scientific article published on 21 January 2014

VAR2CSA and protective immunity against pregnancy-associated Plasmodium falciparum malaria.

scientific article

VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes

scientific article

Virus-like particle display of HER2 induces potent anti-cancer responses.

scientific article published on 5 January 2018

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