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List of works by Nick J Edwards

A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA

scientific article

A defined mechanistic correlate of protection against Plasmodium falciparum malaria in non-human primates

scientific article published on 26 April 2019

A novel chimpanzee adenovirus vector with low human seroprevalence: improved systems for vector derivation and comparative immunogenicity

scientific article (publication date: 2012)

A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques

scientific article published on 01 May 2020

Assessment of chimpanzee adenovirus serotype 63 neutralizing antibodies prior to evaluation of a candidate malaria vaccine regimen based on viral vectors

scientific article

ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans

scientific article

ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

scientific article published on 30 July 2020

Clinical assessment of a recombinant simian adenovirus ChAd63: a potent new vaccine vector

scientific article published on 24 January 2012

Cloning and characterization of hIF2, a human homologue of bacterial translation initiation factor 2, and its interaction with HIV-1 matrix

scientific article

Comparison of clinical and parasitological data from controlled human malaria infection trials

scientific article (publication date: 2012)

Comparison of modeling methods to determine liver-to-blood inocula and parasite multiplication rates during controlled human malaria infection ⬇️

scientific article published on 09 April 2013

Correction for Nébié et al., Assessment of Chimpanzee Adenovirus Serotype 63 Neutralizing Antibodies Prior to Evaluation of a Candidate Malaria Vaccine Regimen Based on Viral Vectors.

scientific article

Demonstration of the Blood-Stage Plasmodium falciparum Controlled Human Malaria Infection Model to Assess Efficacy of the P. falciparum Apical Membrane Antigen 1 Vaccine, FMP2.1/AS01

scientific article published on 4 February 2016

Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals

scientific article

External quality assurance of malaria nucleic acid testing for clinical trials and eradication surveillance

scientific article (publication date: 2014)

Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies.

scientific article

Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions

scientific article published on 2 November 2017

Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909.

scientific article

Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies

scientific article

Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe

scientific article

Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors

scientific article (publication date: 2012)

Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults

scientific article

Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts

scientific article

Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation

scientific article published on January 2013

Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01B With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP.

scientific article published on 15 June 2016

Safety and Immunogenicity of a Novel Recombinant Simian Adenovirus ChAdOx2 as a Vectored Vaccine

scientific article published on 15 May 2019

Safety and efficacy of novel malaria vaccine regimens of RTS,S/AS01B alone, or with concomitant ChAd63-MVA-vectored vaccines expressing ME-TRAP

scientific article published on 09 October 2018

Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal.

scientific article

Translating the immunogenicity of prime-boost immunization with ChAd63 and MVA ME-TRAP from malaria naive to malaria-endemic populations

scientific article

Viral Vector Malaria Vaccines Induce High-Level T Cell and Antibody Responses in West African Children and Infants

scientific article published on February 2017

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