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List of works by Max Nobis

A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.

scientific article published in October 2017

Acute compressive stress activates RHO/ROCK-mediated cellular processes.

scientific article published on 17 February 2018

Advanced intravital subcellular imaging reveals vital three-dimensional signalling events driving cancer cell behaviour and drug responses in live tissue

scientific article published on 28 June 2013

Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis

scientific article

Interaction of p53 with the CCT complex promotes protein folding and wild-type p53 activity

scientific article

Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of src in pancreatic cancer

scientific article published on 7 June 2013

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue

scientific article published on 22 December 2015

MMP-9 triggered micelle-to-fibre transitions for slow release of doxorubicin

scientific article published on 28 October 2014

MMP-9 triggered self-assembly of doxorubicin nanofiber depots halts tumor growth

scientific article

MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer

scientific article published on 01 June 2020

Monitoring the dynamics of Src activity in response to anti-invasive dasatinib treatment at a subcellular level using dual intravital imaging

scientific article

Organotypic collagen I assay: a malleable platform to assess cell behaviour in a 3-dimensional context

scientific article

PtdIns(3,4,5)P3-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis

scientific article published on 23 October 2020

Removing physiological motion from intravital and clinical functional imaging data

scientific article published on 09 July 2018

Shedding new light on RhoA signalling as a drug target in vivo using a novel RhoA-FRET biosensor mouse.

scientific article published on 18 February 2018

Synthesis of Migrastatin and its Macroketone Analogue and In Vivo FRAP Analysis of the Macroketone on E-Cadherin Dynamics

scientific article published on 11 June 2014

TGFβ pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesis

scientific article published on 16 June 2017

The ATG16L1 risk allele associated with Crohn's disease results in a Rac1-dependent defect in dendritic cell migration that is corrected by thiopurines

scientific article published on 20 July 2016

The Rac-FRET mouse reveals tight spatiotemporal control of Rac activity in primary cells and tissues

scientific article published on 13 March 2014

Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.

scientific article published in April 2017

Visualizing Cancer Cell Chemotaxis and Invasion in 2D and 3D.

scientific article published in January 2016

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