List of works - Giovanna R Mallucci

Can mutations of prion protein shed light on its normal function?

scientific article published on 01 December 2009

Cooling-induced SUMOylation of EXOSC10 down-regulates ribosome biogenesis.

scientific article published on 8 February 2016

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

scientific article

Dysfunction and recovery of synapses in prion disease: implications for neurodegeneration.

scientific article published on April 2010

Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease

scientific article

Eukaryotic Elongation Factor 2 Kinase Activity Is Required for the Phenotypes of the Rpl24 Mouse

scientific article published in 2022

Evaluating data integrity in ribosome footprinting datasets through modelled polysome profiles

scientific article published in 2022

Fine-tuning PERK signaling for neuroprotection.

scientific article

Inherited prion disease with an alanine to valine mutation at codon 117 in the prion protein gene

scientific article

M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss

scientific article

Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson's disease

scientific article

Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.

scientific article

Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability.

scientific article published on 9 April 2018

Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice

scientific article

PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia

scientific article

Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity

scientific article

Prion neurodegeneration: starts and stops at the synapse

scientific article published on 02 October 2009

Prions: generation and spread versus neurotoxicity.

scientific article published on 23 May 2014

Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing

scientific article published on 17 August 2018

RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration

scientific article

RNAi for the treatment of prion disease: a window for intervention in neurodegeneration?

scientific article

RTN3 Is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3.

scientific article

Rational targeting for prion therapeutics.

scientific article

Reply: Trazodone to change the risk of neurodegeneration: bedside to bench.

scientific article published on 20 June 2017

Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice

scientific article

Review: Modulating the unfolded protein response to prevent neurodegeneration and enhance memory

scientific article

Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease

scientific article

Spreading proteins in neurodegeneration: where do they take us?

scientific article published on 21 March 2013

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

scientific article

Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice

scientific article

Targeting the kinase insert loop of PERK selectively modulates PERK signaling without systemic toxicity in mice

scientific article published on 11 August 2020

Targeting the unfolded protein response in neurodegeneration: A new approach to therapy

scientific article published on 10 September 2013

The UPR and synaptic dysfunction in neurodegeneration.

scientific article published on 25 March 2016

The role of GPI-anchored PrP C in mediating the neurotoxic effect of scrapie prions in neurons.

scientific article published on 18 September 2009

The unfolded protein response in neurodegenerative disorders - therapeutic modulation of the PERK pathway.

scientific article published on 24 February 2018

The unfolded protein response: mechanisms and therapy of neurodegeneration

scientific article published on 11 May 2016

Therapy for prion diseases: Insights from the use of RNA interference.

scientific article published on 16 July 2009

Update on Creutzfeldt-Jakob disease.

scientific article

miRNAs-19b, -29b-2* and -339-5p show an early and sustained up-regulation in ischemic models of stroke

scientific article

List of works by Giovanna R Mallucci

Can mutations of prion protein shed light on its normal function?

Cooling-induced SUMOylation of EXOSC10 down-regulates ribosome biogenesis.

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

Dysfunction and recovery of synapses in prion disease: implications for neurodegeneration.

Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease

Eukaryotic Elongation Factor 2 Kinase Activity Is Required for the Phenotypes of the Rpl24 Mouse

Evaluating data integrity in ribosome footprinting datasets through modelled polysome profiles

Fine-tuning PERK signaling for neuroprotection.

Inherited prion disease with an alanine to valine mutation at codon 117 in the prion protein gene

M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss

Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson's disease

Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.

Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability.

Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice

PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia

Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity

Prion neurodegeneration: starts and stops at the synapse

Prions: generation and spread versus neurotoxicity.

Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing

RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration

RNAi for the treatment of prion disease: a window for intervention in neurodegeneration?

RTN3 Is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3.

Rational targeting for prion therapeutics.

Reply: Trazodone to change the risk of neurodegeneration: bedside to bench.

Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice

Review: Modulating the unfolded protein response to prevent neurodegeneration and enhance memory

Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease

Spreading proteins in neurodegeneration: where do they take us?

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice

Targeting the kinase insert loop of PERK selectively modulates PERK signaling without systemic toxicity in mice

Targeting the unfolded protein response in neurodegeneration: A new approach to therapy

The UPR and synaptic dysfunction in neurodegeneration.

The role of GPI-anchored PrP C in mediating the neurotoxic effect of scrapie prions in neurons.

The unfolded protein response in neurodegenerative disorders - therapeutic modulation of the PERK pathway.

The unfolded protein response: mechanisms and therapy of neurodegeneration

Therapy for prion diseases: Insights from the use of RNA interference.

Update on Creutzfeldt-Jakob disease.

miRNAs-19b, -29b-2* and -339-5p show an early and sustained up-regulation in ischemic models of stroke