List of works - Ana Barbas

Antigenic response to CT-P13 and infliximab originator in inflammatory bowel disease patients shows similar epitope recognition

scientific article published on 05 June 2018

Biochemical characterization of the RNase II family of exoribonucleases from the human pathogens Salmonella typhimurium and Streptococcus pneumoniae

scientific article published in December 2009

Challenges in Antibody Development against Tn and Sialyl-Tn Antigens

scientific article

Characterization of the functional domains of Escherichia coli RNase II.

scientific article

Characterizing ribonucleases in vitro examples of synergies between biochemical and structural analysis.

scientific article

Comparison of EMSA and SPR for the characterization of RNA-RNase II complexes

scientific article published in August 2010

Correction: Modulating the RNA Processing and Decay by the Exosome: Altering Rrp44/Dis3 Activity and End-Product

scientific article published on 21 August 2015

Determination of key residues for catalysis and RNA cleavage specificity: one mutation turns RNase II into a "SUPER-ENZYME".

scientific article published on 19 May 2009

Evaluation of AAV-mediated delivery of shRNA to target basal-like breast cancer genetic vulnerabilities

scientific article published on 28 May 2019

Expression, purification, crystallization and preliminary diffraction data characterization of Escherichia coli ribonuclease II (RNase II).

scientific article

Modulating the RNA processing and decay by the exosome: altering Rrp44/Dis3 activity and end-product

scientific article

New Insights into the Mechanism of RNA Degradation by Ribonuclease II

scientific article published in Journal of Biological Chemistry

Notch-out for breast cancer therapies.

scientific article

Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glycans terminated by alpha-2-6 sialic acids

scientific article published in Scientific Reports

Production and characterization of a novel Delta-like 1 functional unit as a tool for Notch pathway activation and generation of a specific antibody.

scientific article published on 20 January 2018

RNase R mutants elucidate the catalysis of structured RNA: RNA-binding domains select the RNAs targeted for degradation.

scientific article published on 25 September 2009

Retroviral particles are effectively purified on an affinity matrix containing peptides selected by phage-display

scientific article

Rossmann-fold motifs can confer multiple functions to metabolic enzymes: RNA binding and ribonuclease activity of a UDP-glucose dehydrogenase.

scientific article

Swapping the domains of exoribonucleases RNase II and RNase R: Conferring upon RNase II the ability to degrade ds RNA

scientific article published on 04 April 2011

The Notch ligand DLL1 exerts carcinogenic features in human breast cancer cells.

scientific article published on 20 May 2019

The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.

scientific article

The role of the S1 domain in exoribonucleolytic activity: substrate specificity and multimerization

scientific article published on 22 January 2007

Unravelling the dynamics of RNA degradation by ribonuclease II and its RNA-bound complex.

scientific article

List of works by Ana Barbas

Antigenic response to CT-P13 and infliximab originator in inflammatory bowel disease patients shows similar epitope recognition

Biochemical characterization of the RNase II family of exoribonucleases from the human pathogens Salmonella typhimurium and Streptococcus pneumoniae

Challenges in Antibody Development against Tn and Sialyl-Tn Antigens

Characterization of the functional domains of Escherichia coli RNase II.

Characterizing ribonucleases in vitro examples of synergies between biochemical and structural analysis.

Comparison of EMSA and SPR for the characterization of RNA-RNase II complexes

Correction: Modulating the RNA Processing and Decay by the Exosome: Altering Rrp44/Dis3 Activity and End-Product

Determination of key residues for catalysis and RNA cleavage specificity: one mutation turns RNase II into a "SUPER-ENZYME".

Evaluation of AAV-mediated delivery of shRNA to target basal-like breast cancer genetic vulnerabilities

Expression, purification, crystallization and preliminary diffraction data characterization of Escherichia coli ribonuclease II (RNase II).

Modulating the RNA processing and decay by the exosome: altering Rrp44/Dis3 activity and end-product

New Insights into the Mechanism of RNA Degradation by Ribonuclease II

Notch-out for breast cancer therapies.

Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glycans terminated by alpha-2-6 sialic acids

Production and characterization of a novel Delta-like 1 functional unit as a tool for Notch pathway activation and generation of a specific antibody.

RNase R mutants elucidate the catalysis of structured RNA: RNA-binding domains select the RNAs targeted for degradation.

Retroviral particles are effectively purified on an affinity matrix containing peptides selected by phage-display

Rossmann-fold motifs can confer multiple functions to metabolic enzymes: RNA binding and ribonuclease activity of a UDP-glucose dehydrogenase.

Swapping the domains of exoribonucleases RNase II and RNase R: Conferring upon RNase II the ability to degrade ds RNA

The Notch ligand DLL1 exerts carcinogenic features in human breast cancer cells.

The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.

The role of the S1 domain in exoribonucleolytic activity: substrate specificity and multimerization

Unravelling the dynamics of RNA degradation by ribonuclease II and its RNA-bound complex.