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List of works by Sandrine Cestèle

A rescuable folding defective Nav1.1 (SCN1A) sodium channel mutant causes GEFS+: common mechanism in Nav1.1 related epilepsies?

scientific article published on July 2009

Beta-scorpion toxin effects suggest electrostatic interactions in domain II of voltage-dependent sodium channels.

scientific article published on 14 July 2005

BotIT6: a potent depressant insect toxin from Buthus occitanus tunetanus venom.

scientific article

Delta-atracotoxins from Australian funnel-web spiders compete with scorpion alpha-toxin binding on both rat brain and insect sodium channels

scientific article published in November 1998

Depletion of the Fragile X Mental Retardation Protein in Embryonic Stem Cells Alters the Kinetics of Neurogenesis

scientific article published on 24 September 2016

Depolarization differentially affects allosteric modulation by neurotoxins of scorpion alpha-toxin binding on voltage-gated sodium channels.

scientific article

First chemical synthesis of a scorpion alpha-toxin affecting sodium channels: the Aah I toxin of Androctonus australis hector

scientific article published in November 2004

Gain of Function for the SCN1A/hNav1.1-L1670W Mutation Responsible for Familial Hemiplegic Migraine.

scientific article published on 9 July 2018

Isolation and molecular cloning of beta-neurotoxins from the venom of the scorpion Centruroides suffusus suffusus.

scientific article

Loss-of-function KCNH2 mutation in a family with long QT syndrome, epilepsy, and sudden death.

scientific article published on August 2013

Molecular cloning and functional expression of the alpha-scorpion toxin BotIII: pivotal role of the C-terminal region for its interaction with voltage-dependent sodium channels.

scientific article published in February 2004

Molecular mechanisms of neurotoxin action on voltage-gated sodium channels.

scientific article

New toxins acting on sodium channels from the scorpion Leiurus quinquestriatus hebraeus suggest a clue to mammalian vs insect selectivity.

scientific article published in August 1998

Nonfunctional NaV1.1 familial hemiplegic migraine mutant transformed into gain of function by partial rescue of folding defects

scientific article published on 07 October 2013

Pathophysiological mechanisms of migraine and epilepsy: Similarities and differences.

scientific article published on 9 November 2017

Post-translational dysfunctions in channelopathies of the nervous system

scientific article published on 29 May 2017

Purification, structure and activity of three insect toxins from Buthus occitanus tunetanus venom.

scientific article

Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study

article

Rescuable folding defective NaV1.1 (SCN1A) mutants in epilepsy: properties, occurrence, and novel rescuing strategy with peptides targeted to the endoplasmic reticulum

scientific article

Scorpion alpha-like toxins, toxic to both mammals and insects, differentially interact with receptor site 3 on voltage-gated sodium channels in mammals and insects.

scientific article

Self-limited hyperexcitability: functional effect of a familial hemiplegic migraine mutation of the Nav1.1 (SCN1A) Na+ channel

scientific article

Structure and function of the voltage sensor of sodium channels probed by a beta-scorpion toxin.

scientific article

Toxin III from Leiurus quinquestriatus quinquestriatus: a specific probe for receptor site 3 on insect sodium channels.

scientific article published in June 1997

Voltage sensor-trapping: enhanced activation of sodium channels by beta-scorpion toxin bound to the S3-S4 loop in domain II.

scientific article

Voltage-gated ion channels and gating modifier toxins.

scientific article