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List of works by Mark Pinese

Adar3 Is Involved in Learning and Memory in Mice.

scientific article

Adjuvant chemotherapy in elderly patients with pancreatic cancer.

scientific article

Author Correction: Therapeutic implications of germline genetic findings in cancer

scientific article published on 01 June 2019

BAG-1 predicts patient outcome and tamoxifen responsiveness in ER-positive invasive ductal carcinoma of the breast.

scientific article published on 09 December 2008

Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma

scientific article published on 17 September 2018

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

scientific article published on 12 August 2019

Clinical and molecular characterization of HER2 amplified-pancreatic cancer.

scientific article published on 31 August 2013

Clinical and pathologic features of familial pancreatic cancer

scientific article published on 14 October 2014

Defining the genetic basis of early onset hereditary spastic paraplegia using whole genome sequencing

scientific article published on 28 September 2016

Expression of S100A2 calcium-binding protein predicts response to pancreatectomy for pancreatic cancer

scientific article published on 16 April 2009

Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling.

scientific article published on 9 May 2014

Genomic analyses identify molecular subtypes of pancreatic cancer

scientific article published on 24 February 2016

Genomic stratification and liquid biopsy in a rare adrenocortical carcinoma (ACC) case, with dual lung metastases.

scientific article

High Notch1 protein expression is an early event in breast cancer development and is associated with the HER-2 molecular subtype.

scientific article published in February 2010

Histomolecular phenotypes and outcome in adenocarcinoma of the ampulla of vater

scientific article published on 25 February 2013

Hypermutation In Pancreatic Cancer

scientific article

Identification of PUMA as an estrogen target gene that mediates the apoptotic response to tamoxifen in human breast cancer cells and predicts patient outcome and tamoxifen responsiveness in breast cancer.

scientific article published on 7 March 2011

Identification of functional networks of estrogen- and c-Myc-responsive genes and their relationship to response to tamoxifen therapy in breast cancer

scientific article

Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer

scientific article published on 09 October 2018

Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer.

scientific article

Lost in translation: returning germline genetic results in genome-scale cancer research

scientific article

Messina: a novel analysis tool to identify biologically relevant molecules in disease.

scientific article

PINA v2.0: mining interactome modules.

scientific article published on 8 November 2011

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

scientific article

Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways.

scientific article

Recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer: a model of tumor-host interaction

scientific article

Recurrent SPECC1L-NTRK fusions in paediatric sarcoma and brain tumours

scientific article published on 03 November 2020

Retinoid signaling in pancreatic cancer, injury and regeneration.

scientific article

SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer.

scientific article published on 27 March 2017

Somatic point mutation calling in low cellularity tumors.

scientific article

Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy.

scientific article published on 15 June 2015

The Medical Genome Reference Bank: a whole-genome data resource of 4000 healthy elderly individuals. Rationale and cohort design

scientific article published on 24 October 2018

The effect of resveratrol on a cell model of human aging.

scientific article

The epigenetic agents suberoylanilide hydroxamic acid and 5‑AZA‑2' deoxycytidine decrease cell proliferation, induce cell death and delay the growth of MiaPaCa2 pancreatic cancer cells in vivo.

scientific article

The pseudokinase SgK223 promotes invasion of pancreatic ductal epithelial cells through JAK1/Stat3 signaling

scientific article published on 29 July 2015

Therapeutic implications of germline genetic findings in cancer

scientific article published on 01 June 2019

Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.

scientific article published in April 2017

Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells.

scientific article published on 21 September 2010

Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer

scientific article published on 05 October 2020

Whole genomes redefine the mutational landscape of pancreatic cancer

scientific article published in February 2015

Whole-genome landscape of pancreatic neuroendocrine tumours.

scientific article published on 15 February 2017

qpure: A tool to estimate tumor cellularity from genome-wide single-nucleotide polymorphism profiles

scientific article

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