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List of works by Y. Lynn Wang

Activation of MYC, a bona fide client of HSP90, contributes to intrinsic ibrutinib resistance in mantle cell lymphoma

scientific article published on 01 August 2018

Activation of peroxisome proliferator-activated receptor gamma contributes to the survival of T lymphoma cells by affecting cellular metabolism.

scientific article published on February 2007

Activities of SYK and PLCgamma2 predict apoptotic response of CLL cells to SRC tyrosine kinase inhibitor dasatinib.

scientific article published on 12 January 2010

Amplicon Indel Hunter Is a Novel Bioinformatics Tool to Detect Large Somatic Insertion/Deletion Mutations in Amplicon-Based Next-Generation Sequencing Data.

scientific article

Amplification refractory mutation system, a highly sensitive and simple polymerase chain reaction assay, for the detection of JAK2 V617F mutation in chronic myeloproliferative disorders

scientific article published on April 2007

An evaluation of the Factor V Leiden mutation in a cohort of African-American pregnant women

scientific article published on April 1, 1998

Atypical serum immunofixation patterns frequently emerge in immunomodulatory therapy and are associated with a high degree of response in multiple myeloma

scientific article published on 16 October 2008

B-Cell Lymphoma Patient-Derived Xenograft Models Enable Drug Discovery and Are a Platform for Personalized Therapy

scientific article published on 27 March 2017

BTK inhibition targets in vivo CLL proliferation through its effects on B-cell receptor signaling activity

scientific article published on 25 November 2013

Bone marrow morphology predicts additional chromosomal abnormalities in patients with myelodysplastic syndrome with del(5q)

scientific article published on September 17, 2012

Cerdulatinib pharmacodynamics and relationships to tumor response following oral dosing in patients with relapsed/refractory B-cell malignancies

scientific article published on 17 October 2018

Cerdulatinib, a novel dual SYK/JAK kinase inhibitor, has broad anti-tumor activity in both ABC and GCB types of diffuse large B cell lymphoma.

scientific article published on 5 November 2015

Certification in molecular pathology in the United States: an update from the Association for Molecular Pathology Training and Education Committee.

scientific article

Characterization of ibrutinib-sensitive and -resistant mantle lymphoma cells.

scientific article published on 24 June 2014

Clonal evolution underlying leukemia progression and Richter transformation in patients with ibrutinib-relapsed CLL

scientific article published on 02 May 2017

Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials.

scientific article published on 6 August 2008

Detection of BCL2-IGH using single-round PCR assays.

scientific article published in March 2005

Evaluation of JAK2 in B and T cell neoplasms: identification of JAK2(V617F) mutation of undetermined significance (JMUS) in the bone marrow of three individuals

scientific article published on 21 November 2007

Functional characterization of BTK(C481S) mutation that confers ibrutinib resistance: exploration of alternative kinase inhibitors.

scientific article published on 5 September 2014

Heightened BTK-dependent cell proliferation in unmutated chronic lymphocytic leukemia confers increased sensitivity to ibrutinib

scientific article published on 22 December 2015

Ibrutinib resistance in chronic lymphocytic leukemia

scientific article published on 28 May 2014

Identification of a structurally novel BTK mutation that drives ibrutinib resistance in CLL.

scientific article published on 10 September 2016

JAK2 Mutations are present in all cases of polycythemia vera

scientific article published on 13 December 2007

JAK2(V617F) allele burden in polycythemia vera correlates with grade of myelofibrosis, but is not substantially affected by therapy

scientific article published on 22 July 2010

JAK2V617F allele burden is reduced by busulfan therapy: a new observation using an old drug.

scientific article published on November 2013

Laboratory detection of JAK2V617F in human myeloproliferative neoplasms

scientific article published in January 2013

Laboratory practice guidelines for detecting and reporting JAK2 and MPL mutations in myeloproliferative neoplasms: a report of the Association for Molecular Pathology.

scientific article

Metabolic Detection of Bruton's Tyrosine Kinase Inhibition in Mantle Cell Lymphoma Cells

scientific article published on 12 March 2019

Molecular monitoring of chronic myelogenous leukemia: identification of the most suitable internal control gene for real-time quantification of BCR-ABL transcripts.

scientific article published on May 2006

Molecular monitoring of chronic myeloid leukemia: international standardization of BCR-ABL1 quantitation.

scientific article published on 20 July 2013

NK/T cell non-Hodgkin lymphoma in a HIV-positive patient.

scientific article published on 4 March 2010

Novel bcl-2 breakpoints in patients with follicular lymphoma

scientific article published on 01 April 1998

Predicting Prognosis in Chronic Lymphocytic Leukemia in the Contemporary Era.

scientific article published on 07 May 2015

Prognosis in Chronic Lymphocytic Leukemia-Reply.

scientific article published in October 2015

Regulation of self-tolerance by CD80/CD86 interactions

scientific article published on December 1997

Requirements for U2 snRNP addition to yeast pre-mRNA.

scientific article published in August 1992

SYK inhibition and response prediction in diffuse large B-cell lymphoma

scientific article published on October 24, 2011

Splenic extramedullary hematopoietic proliferation in Philadelphia chromosome-negative myeloproliferative neoplasms: heterogeneous morphology and cytological composition.

scientific article published on 2 March 2012

Strongyloides stercoralis infection presenting as an unusual cause of massive upper gastrointestinal bleeding in an immunosuppressed patient: a case report.

scientific article published in January 2013

The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis

scientific article published on 09 August 2007

Thiazolidinedione activation of peroxisome proliferator-activated receptor gamma can enhance mitochondrial potential and promote cell survival.

scientific article published on 24 June 2002

To Live or to Die: Prosurvival Activity of PPARgamma in Cancers

scientific article published on January 2008

Translating Trial-Based Molecular Monitoring Into Clinical Practice: Importance of International Standards and Practical Considerations for Community Practitioners

scientific article published on May 10, 2011

Tyrosine kinase inhibition in diffuse large B-cell lymphoma: molecular basis for antitumor activity and drug resistance of dasatinib.

scientific article

XPO1 Inhibitor Selinexor Overcomes Intrinsic Ibrutinib Resistance in Mantle Cell Lymphoma via Nuclear Retention of IκB

scientific article published on 01 December 2018