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List of works by Alastair Droop

A Case-Matched Gender Comparison Transcriptomic Screen Identifies eIF4E and eIF5 as Potential Prognostic Markers in Male Breast Cancer ⬇️

scientific article published on 16 December 2016

A Detailed Analysis of Gene Expression in Human Basal, Luminal, and Stromal Cell Populations from Benign Prostatic Hyperplasia Tissues and Comparisons with Cultured Basal Cells ⬇️

scientific article

ANGI-14. A GSK-3/b-CATENIN/ARHGAP AXIS REGULATES GLIOBLASTOMA INVASION ⬇️

ATPS-48A HIGH-THROUGHPUT SCREEN IDENTIFIES microRNA-1300 AS A POTENTIAL THERAPEUTIC microRNA CAUSING CYTOKINESIS FAILURE AND APOPTOSIS IN GLIOBLASTOMA CELLS.

scientific article

Benchmarking pipelines for subclonal deconvolution of bulk tumour sequencing data

scientific article published on 04 November 2021

CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation

scientific article published on 23 March 2021

Changes in plasma chemokine C-C motif ligand 2 levels during treatment with eicosapentaenoic acid predict outcome in patients undergoing surgery for colorectal cancer liver metastasis ⬇️

scientific article published on 04 April 2016

Chemically induced neurite-like outgrowth reveals a multicellular network function in patient-derived glioblastoma cells

scientific article published on 10 October 2019

Chemically-induced Neurite-like Outgrowth Reveals Multicellular Network Function in Patient-derived Glioblastoma Cells

scientific article published on 10 November 2018

Conserved two-step regulatory mechanism of human epithelial differentiation ⬇️

scientific article published on 6 February 2014

Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia

scientific article published on 30 April 2021

DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation.

scientific article published on 24 January 2014

Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq ⬇️

scientific article

Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma

scientific article published on 16 December 2019

Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions.

scientific article published on 20 May 2008

Genetic and Environmental Determinants of Immune Response to Cutaneous Melanoma

scientific article published on 17 February 2019

Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency ⬇️

scientific article published in November 2017

Hematopoietic stem cell gene therapy for brain metastases using myeloid cell-specific gene promoters

scientific article published on 10 September 2019

High-Resolution Copy Number Patterns From Clinically Relevant FFPE Material.

scientific article published on 20 June 2019

How to analyse the spatiotemporal tumour samples needed to investigate cancer evolution: A case study using paired primary and recurrent glioblastoma ⬇️

scientific article

Identification of transcriptional targets of GSK3 involved in glioblastoma invasion

KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice ⬇️

scientific article published on 01 August 2018

Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature ⬇️

scientific article published on 28 November 2014

Prognostic microRNAs in high-grade glioma reveal a link to oligodendrocyte precursor differentiation.

scientific article

Properties of biological mutation networks and their implications for ALife

scientific article

RNA sequencing and functional studies of patient-derived cells reveal that neurexin-1 and regulators of this pathway are associated with poor outcomes in Ewing sarcoma

scientific article published on 17 August 2021

Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance. ⬇️

scientific article

Simulation of heterogeneous tumour genomes with HeteroGenesis and in silico whole exome sequencing ⬇️

scientific article published in 2019

Stanniocalcin 2 expression is associated with a favourable outcome in male breast cancer ⬇️

article published in 2018

The calcium sensor STIM1 is regulated by androgens in prostate stromal cells

scientific article

The mutational signature profile of known and suspected human carcinogens in mice

scientific article published on 28 September 2020

The small molecule KHS101 induces bioenergetic dysfunction in glioblastoma cells through inhibition of mitochondrial HSPD1

scientific article published on 18 October 2017

Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastases ⬇️

scientific article published on 2 February 2017

Yeast ntr1/spp382 mediates prp43 function in postspliceosomes.

scientific article

β-Catenin-mediated immune evasion pathway frequently operates in primary cutaneous melanomas. ⬇️

scientific article published on 16 April 2018

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