List of works - Derek J. Richard

A distinct ssDNA/RNA binding interface in the Nsp9 protein from SARS-CoV-2

scientific article published on 13 August 2021

A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP.

scientific article published on 22 March 2007

ATM mediated phosphorylation of CHD4 contributes to genome maintenance

scientific article published on 10 January 2011

Antiproton induced DNA damage: proton like in flight, carbon-ion like near rest.

scientific article published on January 2013

BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability

scientific article

BRCA1 is an essential mediator of vinorelbine-induced apoptosis in mesothelioma.

scientific article

Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising

scientific article

Circulating tumour cell clusters: Insights into tumour dissemination and metastasis

scientific article published on 03 November 2020

Circulating tumour cells, their role in metastasis and their clinical utility in lung cancer.

scientific article published on 29 December 2011

Cold atmospheric plasma for preventing infection of viruses that use ACE2 for entry

scientific article published on 14 March 2022

Conformational flexibility revealed by the crystal structure of a crenarchaeal RadA

scientific article

Contribution of DEAF1 structural domains to the interaction with the breast cancer oncogene LMO4.

scientific article

Crystallization and preliminary X-ray diffraction studies of Hje, a HolliDay junction resolving enzyme from Sulfolobus solfataricus

scientific article

Elevating CDCA3 levels in non-small cell lung cancer enhances sensitivity to platinum-based chemotherapy

scientific article published on 28 May 2021

Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small-Cell Lung Cancer (NSCLC)

scientific article published on 25 September 2020

Functions and therapeutic roles of exosomes in cancer.

scientific article

Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature

scientific article

Genome stability pathways in head and neck cancers

scientific article

HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response

scientific article

Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks.

scientific article

Human single-stranded DNA binding proteins are essential for maintaining genomic stability

scientific article

INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells

scientific article published in April 2012

INTS3 controls the hSSB1-mediated DNA damage response

scientific article published on 28 September 2009

Identification of a BRCA1-mRNA splicing complex required for efficient DNA repair and maintenance of genomic stability

scientific article

Involvement of Exo1b in DNA damage-induced apoptosis

scientific article published on April 2009

Kruppel-associated Box (KRAB)-associated co-repressor (KAP-1) Ser-473 phosphorylation regulates heterochromatin protein 1β (HP1-β) mobilization and DNA repair in heterochromatin

scientific article

Modeling 5-FU clearance during a chronomodulated infusion

scientific article

Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis

scientific article

Novel insight into the composition of human single-stranded DNA-binding protein 1 (hSSB1)-containing protein complexes

scientific article

Nucleolar caspase-2: Protecting us from DNA damage.

scientific article

Nucleophosmin: from structure and function to disease development

scientific article

Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation

scientific article published on 12 December 2014

PARP inhibition induces BAX/BAK-independent synthetic lethality of BRCA1-deficient non-small cell lung cancer

scientific article published on 27 June 2011

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks

scientific article

Physical and functional interaction of the archaeal single-stranded DNA-binding protein SSB with RNA polymerase

scientific article published on 10 February 2004

Recent advances in cancer therapy targeting proteins involved in DNA double-strand break repair.

scientific article

Rodent blood-stage Plasmodium survive in dendritic cells that infect naive mice

scientific article

SASH1 is a prognostic indicator and potential therapeutic target in non-small cell lung cancer

scientific article published on 29 October 2020

Sex Hormone Binding Globulin Modifies Testosterone Action and Metabolism in Prostate Cancer Cells

scientific article

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

scientific article

Spatiotemporal investigations of DNA damage repair using microbeams

scientific article published on 12 December 2010

Structure of Hjc, a Holliday junction resolvase, from Sulfolobus solfataricus

scientific article

Substrate recognition and catalysis by the Holliday junction resolving enzyme Hje.

scientific article published on 12 October 2004

The Impact of Rare Human Variants on Barrier-To-Auto-Integration Factor 1 (Banf1) Structure and Function

scientific article published on 08 November 2021

The role of DNA repair pathways in cisplatin resistant lung cancer

scientific article published on 18 October 2014

The structural basis of DNA binding by the single-stranded DNA-binding protein from Sulfolobus solfataricus

scientific article

Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer

scientific article

WT1 interacts with MAD2 and regulates mitotic checkpoint function

scientific article

hSSB1 associates with and promotes stability of the BLM helicase

scientific article

hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity

scientific article

hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex

scientific article

hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage

scientific article published on 12 October 2021

List of works by Derek J. Richard

A distinct ssDNA/RNA binding interface in the Nsp9 protein from SARS-CoV-2

A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP.

ATM mediated phosphorylation of CHD4 contributes to genome maintenance

Antiproton induced DNA damage: proton like in flight, carbon-ion like near rest.

BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability

BRCA1 is an essential mediator of vinorelbine-induced apoptosis in mesothelioma.

Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising

Circulating tumour cell clusters: Insights into tumour dissemination and metastasis

Circulating tumour cells, their role in metastasis and their clinical utility in lung cancer.

Cold atmospheric plasma for preventing infection of viruses that use ACE2 for entry

Conformational flexibility revealed by the crystal structure of a crenarchaeal RadA

Contribution of DEAF1 structural domains to the interaction with the breast cancer oncogene LMO4.

Crystallization and preliminary X-ray diffraction studies of Hje, a HolliDay junction resolving enzyme from Sulfolobus solfataricus

Elevating CDCA3 levels in non-small cell lung cancer enhances sensitivity to platinum-based chemotherapy

Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small-Cell Lung Cancer (NSCLC)

Functions and therapeutic roles of exosomes in cancer.

Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature

Genome stability pathways in head and neck cancers

HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response

Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks.

Human single-stranded DNA binding proteins are essential for maintaining genomic stability

INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells

INTS3 controls the hSSB1-mediated DNA damage response

Identification of a BRCA1-mRNA splicing complex required for efficient DNA repair and maintenance of genomic stability

Involvement of Exo1b in DNA damage-induced apoptosis

Kruppel-associated Box (KRAB)-associated co-repressor (KAP-1) Ser-473 phosphorylation regulates heterochromatin protein 1β (HP1-β) mobilization and DNA repair in heterochromatin

Modeling 5-FU clearance during a chronomodulated infusion

Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis

Novel insight into the composition of human single-stranded DNA-binding protein 1 (hSSB1)-containing protein complexes

Nucleolar caspase-2: Protecting us from DNA damage.

Nucleophosmin: from structure and function to disease development

Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation

PARP inhibition induces BAX/BAK-independent synthetic lethality of BRCA1-deficient non-small cell lung cancer

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks

Physical and functional interaction of the archaeal single-stranded DNA-binding protein SSB with RNA polymerase

Recent advances in cancer therapy targeting proteins involved in DNA double-strand break repair.

Rodent blood-stage Plasmodium survive in dendritic cells that infect naive mice

SASH1 is a prognostic indicator and potential therapeutic target in non-small cell lung cancer

Sex Hormone Binding Globulin Modifies Testosterone Action and Metabolism in Prostate Cancer Cells

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

Spatiotemporal investigations of DNA damage repair using microbeams

Structure of Hjc, a Holliday junction resolvase, from Sulfolobus solfataricus

Substrate recognition and catalysis by the Holliday junction resolving enzyme Hje.

The Impact of Rare Human Variants on Barrier-To-Auto-Integration Factor 1 (Banf1) Structure and Function

The role of DNA repair pathways in cisplatin resistant lung cancer

The structural basis of DNA binding by the single-stranded DNA-binding protein from Sulfolobus solfataricus

Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer

WT1 interacts with MAD2 and regulates mitotic checkpoint function

hSSB1 associates with and promotes stability of the BLM helicase

hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity

hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex

hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage