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List of works by Erik Hooijberg

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Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation

scientific article
Codon modification of T cell receptors allows enhanced functional expression in transgenic human T cells

scientific article published on 2 February 2006
Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptase

scientific article
Signal-regulatory protein alpha-CD47 interactions are required for the transmigration of monocytes across cerebral endothelium

scientific journal article
Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory act

scientific article
Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T-lymphocytes and preserved MHC class I antigen expression

scientific article published in August 2008
Glycan-modified liposomes boost CD4+ and CD8+ T-cell responses by targeting DC-SIGN on dendritic cells

scientific article published on 15 February 2012
Reduced human leukocyte antigen expression in advanced-stage Ewing sarcoma: implications for immune recognition

scientific article published on June 2009
Changing T cell specificity by retroviral T cell receptor display

scientific article
Expression of the apoptosis inhibitor protease inhibitor 9 predicts clinical outcome in vaccinated patients with stage III and IV melanoma

scientific article
In vitro priming of tumor-specific cytotoxic T lymphocytes using allogeneic dendritic cells derived from the human MUTZ-3 cell line.

scientific article published on 9 February 2006
Inducing antitumor T cell immunity: comparative functional analysis of interstitial versus Langerhans dendritic cells in a human cell line model.

scientific article
IL-21 promotes the expansion of CD27+ CD28+ tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells.

scientific article published on 12 February 2013
In vitro generation and life span extension of human papillomavirus type 16-specific, healthy donor-derived CTL clones.

scientific article published on September 2003
IFN-gamma-producing human invariant NKT cells promote tumor-associated antigen-specific cytotoxic T cell responses.

scientific article
Preservation and redirection of HPV16E7-specific T cell receptors for immunotherapy of cervical cancer

scientific article
Dendritic cells transfected with interleukin-12 and tumor-associated antigen messenger RNA induce high avidity cytotoxic T cells.

scientific article published on 12 October 2006
Enrichment of an antigen-specific T cell response by retrovirally transduced human dendritic cells.

scientific article published in July 1999
Topical rather than intradermal application of the TLR7 ligand imiquimod leads to human dermal dendritic cell maturation and CD8+ T-cell cross-priming

scientific article published on 24 June 2014
NFAT-controlled expression of GFP permits visualization and isolation of antigen-stimulated primary human T cells

scientific article published on 01 July 2000
Generation of regulatory gut-homing human T lymphocytes using ex vivo interleukin 10 gene transfer

scientific article published on 01 December 2002
IL-10 conditioning of human skin affects the distribution of migratory dendritic cell subsets and functional T cell differentiation.

scientific article
Plasmacytoid dendritic cells are present in cervical carcinoma and become activated by human papillomavirus type 16 virus-like particles.

scientific article published in March 2005
Notch controls generation and function of human effector CD8+ T cells

scientific article published on 04 February 2013
Clinical effects of adjuvant active specific immunotherapy differ between patients with microsatellite-stable and microsatellite-instable colon cancer

scientific article
Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice.

scientific article published on March 2004
Generating HPV specific T helper cells for the treatment of HPV induced malignancies using TCR gene transfer.

scientific article
Effector memory T-cell frequencies in relation to tumour stage, location and HPV status in HNSCC patients

scientific article published on 26 November 2012
Prognostic value of BRAF and KRAS mutation status in stage II and III microsatellite instable colon cancers.

scientific article published on 16 September 2015
Gene-dosage dependent overexpression at the 13q amplicon identifies DIS3 as candidate oncogene in colorectal cancer progression.

scientific article published on 29 January 2014
Tumor associated antigen and interleukin-12 mRNA transfected dendritic cells enhance effector function of natural killer cells and antigen specific T-cells

scientific article published on 21 March 2008
Apoptotic blebs from leukemic cells as a preferred source of tumor-associated antigen for dendritic cell-based vaccines

scientific article published on 03 January 2014
Inhibition of the intrinsic apoptosis pathway downstream of caspase-9 activation causes chemotherapy resistance in diffuse large B-cell lymphoma.

scientific article published on December 2007
Selective transduction of dendritic cells in human lymph nodes and superior induction of high-avidity melanoma-reactive cytotoxic T cells by a CD40-targeted adenovirus

scientific article published on 01 September 2010
Functional characterization of a STAT3-dependent dendritic cell-derived CD14(+) cell population arising upon IL-10-driven maturation.

scientific article
Extent and Location of Tumor-Infiltrating Lymphocytes in Microsatellite-Stable Colon Cancer Predict Outcome to Adjuvant Active Specific Immunotherapy

scientific article published on 29 September 2015
Eradication of large human B cell tumors in nude mice with unconjugated CD20 monoclonal antibodies and interleukin 2

scientific article published on 01 June 1995
Genomic stability and functional activity may be lost in telomerase-transduced human CD8+ T lymphocytes

scientific article published on 7 July 2005
Exposure of CD34+ precursors to cytostatic anthraquinone-derivatives induces rapid dendritic cell differentiation: implications for cancer immunotherapy.

scientific article
Retargeting of a T cell line by anti MAGE-3/HLA-A2 alpha beta TCR gene transfer

scientific article published on May 2000
Constitutively active STAT5b induces cytokine-independent growth of the acute myeloid leukemia-derived MUTZ-3 cell line and accelerates its differentiation into mature dendritic cells.

scientific article published on March 2006
Expansion of dendritic cell precursors from human CD34(+) progenitor cells isolated from healthy donor blood; growth factor combination determines proliferation rate and functional outcome.

scientific article published in August 2002
Small-molecule XIAP antagonist restores caspase-9 mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cells

scientific article
Highly specific and potently activating Vγ9Vδ2-T cell specific nanobodies for diagnostic and therapeutic applications.

scientific article published on 30 June 2016
A bispecific nanobody approach to leverage the potent and widely applicable tumor cytolytic capacity of Vγ9Vδ2-T cells.

scientific article published on 20 October 2017
Increased cytotoxic capacity of tumor antigen specific human T cells after in vitro stimulation with IL21 producing dendritic cells

scientific article published on 29 January 2013
Exploring dendritic cell based vaccines targeting survivin for the treatment of head and neck cancer patients.

scientific article published on 20 June 2013
Priming of PRAME- and WT1-specific CD8(+) T cells in healthy donors but not in AML patients in complete remission: Implications for immunotherapy

scientific article published in April 2013
Integration vectors for antibody chimerization by homologous recombination in hybridoma cells

scientific article published on 01 March 1995
Identification of a potential human telomerase reverse transcriptase-derived, HLA-A1-restricted cytotoxic T-lymphocyte epitope

scientific article published on 22 February 2005

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