Search filters

List of works by Erik Hooijberg

A bispecific nanobody approach to leverage the potent and widely applicable tumor cytolytic capacity of Vγ9Vδ2-T cells.

scientific article published on 20 October 2017

A single amino acid substitution improves the in vivo immunogenicity of the HPV16 oncoprotein E7(11-20) cytotoxic T lymphocyte epitope

scientific article published on 11 April 2005

Absence of Granzyme B positive tumour-infiltrating lymphocytes in primary melanoma excisional biopsies is strongly associated with the presence of sentinel lymph node metastasis.

scientific article

Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion

scientific article published on 09 September 2020

Antigen gene transfer to human plasmacytoid dendritic cells using recombinant adenovirus and vaccinia virus vectors.

scientific article

Apoptotic blebs from leukemic cells as a preferred source of tumor-associated antigen for dendritic cell-based vaccines

scientific article published on 03 January 2014

Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival

scientific article published on 11 September 2018

Autologous tumor cell vaccination combined with systemic CpG-B and IFN-α promotes immune activation and induces clinical responses in patients with metastatic renal cell carcinoma: a phase II trial.

scientific article

Breast adipocyte size associates with ipsilateral invasive breast cancer risk after ductal carcinoma in situ

scientific article published on 22 March 2021

Changing T cell specificity by retroviral T cell receptor display

scientific article

Characterization of a series of isotype switch variants of a new CD20 monoclonal antibody

scientific article published on 01 February 1996

Clinical effects of adjuvant active specific immunotherapy differ between patients with microsatellite-stable and microsatellite-instable colon cancer

scientific article

Codon modification of T cell receptors allows enhanced functional expression in transgenic human T cells

scientific article published on 2 February 2006

Constitutively active STAT5b induces cytokine-independent growth of the acute myeloid leukemia-derived MUTZ-3 cell line and accelerates its differentiation into mature dendritic cells.

scientific article published on March 2006

Construction and characterization of a fusion protein of single-chain anti-CD20 antibody and human beta-glucuronidase for antibody-directed enzyme prodrug therapy

scientific article published on July 1998

Correction to: Autologous tumor cell vaccination combined with systemic CpG-B and IFN-α promotes immune activation and induces clinical responses in patients with metastatic renal cell carcinoma: a phase II trial

scientific article published on 01 June 2019

Dendritic cells transfected with interleukin-12 and tumor-associated antigen messenger RNA induce high avidity cytotoxic T cells.

scientific article published on 12 October 2006

Differential capacity of human interleukin-4 and interferon-α monocyte-derived dendritic cells for cross-presentation of free versus cell-associated antigen

scientific article published on 28 July 2015

Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation

scientific article

Effector memory T-cell frequencies in relation to tumour stage, location and HPV status in HNSCC patients

scientific article published on 26 November 2012

Enhanced antitumor effects of CD20 over CD19 monoclonal antibodies in a nude mouse xenograft model

scientific article published on 01 February 1995

Enrichment of an antigen-specific T cell response by retrovirally transduced human dendritic cells.

scientific article published in July 1999

Eradication of large human B cell tumors in nude mice with unconjugated CD20 monoclonal antibodies and interleukin 2

scientific article published on 01 June 1995

Expansion of dendritic cell precursors from human CD34(+) progenitor cells isolated from healthy donor blood; growth factor combination determines proliferation rate and functional outcome.

scientific article published in August 2002

Exploring dendritic cell based vaccines targeting survivin for the treatment of head and neck cancer patients.

scientific article published on 20 June 2013

Exposure of CD34+ precursors to cytostatic anthraquinone-derivatives induces rapid dendritic cell differentiation: implications for cancer immunotherapy.

scientific article

Expression of a functional mouse-human chimeric anti-CD19 antibody in the milk of transgenic mice

scientific article published on 01 April 2000

Expression of c-FLIP is primarily detected in diffuse large B-cell lymphoma and Hodgkin's lymphoma and correlates with lack of caspase 8 activation

scientific article published on 01 December 2007

Expression of the apoptosis inhibitor protease inhibitor 9 predicts clinical outcome in vaccinated patients with stage III and IV melanoma

scientific article

Extent and Location of Tumor-Infiltrating Lymphocytes in Microsatellite-Stable Colon Cancer Predict Outcome to Adjuvant Active Specific Immunotherapy

scientific article published on 29 September 2015

Extent and location of tumor infiltrating lymphocytes in microsatellite stable colon cancer predict outcome to adjuvant active specific immunotherapy.

scientific article published on 4 November 2015

Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T-lymphocytes and preserved MHC class I antigen expression

scientific article published in August 2008

Functional characterization of a STAT3-dependent dendritic cell-derived CD14(+) cell population arising upon IL-10-driven maturation.

scientific article

Gene-dosage dependent overexpression at the 13q amplicon identifies DIS3 as candidate oncogene in colorectal cancer progression.

scientific article published on 29 January 2014

Generating HPV specific T helper cells for the treatment of HPV induced malignancies using TCR gene transfer.

scientific article

Generation of regulatory gut-homing human T lymphocytes using ex vivo interleukin 10 gene transfer

scientific article published on 01 December 2002

Genomic stability and functional activity may be lost in telomerase-transduced human CD8+ T lymphocytes

scientific article published on 7 July 2005

Glycan-modified liposomes boost CD4+ and CD8+ T-cell responses by targeting DC-SIGN on dendritic cells

scientific article published on 15 February 2012

HLA class II expression on tumor cells and low numbers of tumor-associated macrophages predict clinical outcome in oropharyngeal cancer.

scientific article published on 14 December 2018

High susceptibility of c-KIT+CD34+ precursors to prolonged doxorubicin exposure interferes with Langerhans cell differentiation in a human cell line model.

scientific article published on 24 March 2011

Highly specific and potently activating Vγ9Vδ2-T cell specific nanobodies for diagnostic and therapeutic applications.

scientific article published on 30 June 2016

Human soluble TRAIL/Apo2L induces apoptosis in a subpopulation of chemotherapy refractory nodal diffuse large B-cell lymphomas, determined by a highly sensitive in vitro apoptosis assay

scientific article published on August 2006

Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice.

scientific article published on March 2004

IFN-gamma-producing human invariant NKT cells promote tumor-associated antigen-specific cytotoxic T cell responses.

scientific article

IL-10 conditioning of human skin affects the distribution of migratory dendritic cell subsets and functional T cell differentiation.

scientific article

IL-21 in cancer immunotherapy: At the right place at the right time.

scientific article published on 16 April 2013

IL-21 promotes the expansion of CD27+ CD28+ tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells.

scientific article published on 12 February 2013

Identification and characterization of ErbB-3-binding protein-1 as a target for immunotherapy

scientific article

Identification of a potential human telomerase reverse transcriptase-derived, HLA-A1-restricted cytotoxic T-lymphocyte epitope

scientific article published on 22 February 2005

Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptase

scientific article

Immunotherapy for head and neck cancer patients: shifting the balance

scientific article published on January 2013

Improved Induction of Anti-Melanoma T Cells by Adenovirus-5/3 Fiber Modification to Target Human DCs

scientific article published on 18 July 2018

In situ loading of skin dendritic cells with apoptotic bleb-derived antigens for the induction of tumor-directed immunity.

scientific article published on 3 July 2014

In vitro generation and life span extension of human papillomavirus type 16-specific, healthy donor-derived CTL clones.

scientific article published on September 2003

In vitro priming of tumor-specific cytotoxic T lymphocytes using allogeneic dendritic cells derived from the human MUTZ-3 cell line.

scientific article published on 9 February 2006

Increased cytotoxic capacity of tumor antigen specific human T cells after in vitro stimulation with IL21 producing dendritic cells

scientific article published on 29 January 2013

Inducing antitumor T cell immunity: comparative functional analysis of interstitial versus Langerhans dendritic cells in a human cell line model.

scientific article

Inhibition of the intrinsic apoptosis pathway downstream of caspase-9 activation causes chemotherapy resistance in diffuse large B-cell lymphoma.

scientific article published on December 2007

Integration vectors for antibody chimerization by homologous recombination in hybridoma cells

scientific article published on 01 March 1995

Interleukin-12 increases proliferation and interferon-gamma production but not cytolytic activity of human antigen-specific effector memory cytotoxic T lymphocytes: power of the effect depends on the functional avidity of the T cell and the antigen

scientific article published on 01 November 2005

Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory act

scientific article

Lysis of syngeneic tumor B cells by autoreactive cytotoxic T lymphocytes specific for a CD19 antigen-derived synthetic peptide

scientific article published on 01 September 1996

NFAT-controlled expression of GFP permits visualization and isolation of antigen-stimulated primary human T cells

scientific article published on 01 July 2000

Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma

scientific article published on 22 December 2021

Notch controls generation and function of human effector CD8+ T cells

scientific article published on 04 February 2013

Oncogenic Role of miR-15a-3p in 13q Amplicon-Driven Colorectal Adenoma-to-Carcinoma Progression

scientific article published on 6 July 2015

Plasmacytoid dendritic cells are present in cervical carcinoma and become activated by human papillomavirus type 16 virus-like particles.

scientific article published in March 2005

Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7.

scientific article published on 30 April 2012

Preoperative ipilimumab plus nivolumab in locoregionally advanced urothelial cancer: the NABUCCO trial

scientific article published on 12 October 2020

Preservation and redirection of HPV16E7-specific T cell receptors for immunotherapy of cervical cancer

scientific article

Priming of PRAME- and WT1-specific CD8(+) T cells in healthy donors but not in AML patients in complete remission: Implications for immunotherapy

scientific article published in April 2013

Prognostic value of BRAF and KRAS mutation status in stage II and III microsatellite instable colon cancers.

scientific article published on 16 September 2015

Promiscuous behavior of HPV16E6 specific T cell receptor beta chains hampers functional expression in TCR transgenic T cells, which can be restored in part by genetic modification.

scientific article published in January 2010

Reduced human leukocyte antigen expression in advanced-stage Ewing sarcoma: implications for immune recognition

scientific article published on June 2009

Retargeting of a T cell line by anti MAGE-3/HLA-A2 alpha beta TCR gene transfer

scientific article published on May 2000

Selective transduction of dendritic cells in human lymph nodes and superior induction of high-avidity melanoma-reactive cytotoxic T cells by a CD40-targeted adenovirus

scientific article published on 01 September 2010

Signal-regulatory protein alpha-CD47 interactions are required for the transmigration of monocytes across cerebral endothelium

scientific journal article

Small-molecule XIAP antagonist restores caspase-9 mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cells

scientific article

Topical rather than intradermal application of the TLR7 ligand imiquimod leads to human dermal dendritic cell maturation and CD8+ T-cell cross-priming

scientific article published on 24 June 2014

Tumor associated antigen and interleukin-12 mRNA transfected dendritic cells enhance effector function of natural killer cells and antigen specific T-cells

scientific article published on 21 March 2008

Paulina is supported by:

About Paulina

Help