List of works by Patricia Ernst

A potential role for Elf-1 in terminal transferase gene regulation

scientific article published on November 1996

Acat1 gene ablation in mice increases hematopoietic progenitor cell proliferation in bone marrow and causes leukocytosis.

scientific article published on 11 July 2013

An MLL-dependent network sustains hematopoiesis.

scientific article published on 06 June 2013

Both LyF-1 and an Ets protein interact with a critical promoter element in the murine terminal transferase gene.

scientific article

Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model

scholarly article

Cell context in the control of self-renewal and proliferation regulated by MLL1.

scientific article published on 12 August 2013

Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells

scientific article published on 11 February 2009

Combinatorial regulation of transcription II: The immunoglobulin mu heavy chain gene.

scientific article published on May 1995

Combinatorial regulation of transcription. I: General aspects of transcriptional control.

scientific article

Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.

scientific article

Conserved higher-order chromatin regulates NMDA receptor gene expression and cognition.

scientific article

Context, Context, Context: New Gene Programs Linked to Bad Behavior in MLL-AF9-Initiated Leukemia.

scientific article published in July 2016

Developmentally induced Mll1 loss reveals defects in postnatal haematopoiesis ⬇️

scientific article published on August 19, 2010

Distinct functions of histone H3, lysine 4 methyltransferases in normal and malignant hematopoiesis

scientific article published on April 2017

Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells

scientific article published on August 2013

Down-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activator

scientific article

Embryonic stem cell-derived hematopoietic stem cells

scholarly article

Harnessing gene repression to inhibit leukemia

scientific article published on 01 April 2015

Hematopoietic transformation in the absence of MLL1/KMT2A: distinctions in target gene reactivation

scientific article published on 04 June 2019

IFN-alpha wakes up sleeping hematopoietic stem cells.

scientific article published on June 2009

Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets

scientific article

Leukemia and hematopoietic stem cells: balancing proliferation and quiescence.

scientific article published on January 2008

MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein

scientific article

MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.

scientific article

MLL1 Promotes IL-7 Responsiveness and Survival during B Cell Differentiation.

scientific article published on 19 January 2018

MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia

scientific article published on 29 February 2016

MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia

scientific article published in June 2017

Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development

scientific article published on December 1999

NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis.

scientific article published on 15 November 2016

Neuronal Deletion of Kmt2a/Mll1 Histone Methyltransferase in Ventral Striatum is Associated with Defective Spike-Timing-Dependent Striatal Synaptic Plasticity, Altered Response to Dopaminergic Drugs, and Increased Anxiety.

scientific article published on 3 August 2016

Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory

scientific journal article

Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization

scientific article

Runx1 loss minimally impacts long-term hematopoietic stem cells

scientific article published on December 2011

SET/MLL family proteins in hematopoiesis and leukemia.

scientific article published on 31 October 2016

The histone methyltransferase activity of MLL1 is dispensable for hematopoiesis and leukemogenesis

scientific article published on 9 May 2014

The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene

scientific article

Two decades of leukemia oncoprotein epistasis: the MLL1 paradigm for epigenetic deregulation in leukemia.

scientific article

WRAD: enabler of the SET1-family of H3K4 methyltransferases

scientific article

cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes

scientific article published on September 2003

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