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List of works by Leandro Sastre

A Serum Response Factor homolog is required for spore differentiation in Dictyostelium

scientific article published in October 1998

A dyskerin motif reactivates telomerase activity in X-linked dyskeratosis congenita and in telomerase-deficient human cells.

scientific article published on 5 December 2007

A partial genomic DNA clone for the alpha subunit of the mouse complement receptor type 3 and cellular adhesion molecule Mac-1.

scientific article

A serum response factor homologue is expressed in ectodermal tissues during development of the crustacean Artemia franciscana

scientific article published on September 2000

Actin gene structure in two Artemia species, A. franciscana and A. parthenogenetica.

scientific article published on September 1996

Biological Activity of the Alternative Promoters of the Dictyostelium discoideum Adenylyl Cyclase A Gene

scientific article published on 3 February 2016

Biomarkers of erlotinib response in non-small cell lung cancer tumors that do not harbor the more common epidermal growth factor receptor mutations.

scientific article published on March 2015

Cancer stem cells and cisplatin-resistant cells isolated from non-small-lung cancer cell lines constitute related cell populations

scientific article

Characterization of a functional serum response element in the Actin403 gene promoter from the crustacean Artemia franciscana.

scientific article published on May 2001

Clinical implications of the ENCODE project

scientific article published on October 11, 2012

Cloning of a cDNA encoding an Artemia franciscana Na/K ATPase alpha-subunit

scientific article

Complementary DNA cloning of a protein highly homologous to mammalian sarcoplasmic reticulum Ca-ATPase from the crustacean Artemia

scholarly article

Defects in mTR stability and telomerase activity produced by the Dkc1 A353V mutation in dyskeratosis congenita are rescued by a peptide from the dyskerin TruB domain

scientific article published on 24 July 2012

Developmental changes in poly(A) polymerase activity in Artemia.

scientific article published in September 1983

Dictyostelium discoideum developmentally regulated genes whose expression is dependent on MADS box transcription factor SrfA.

scientific article published on December 2003

Differential expression of a gene highly homologous to c-ras during the development of the brine shrimp Artemia

scientific article

Differentiation of myeloid cells is accompanied by increased levels of pp60c-src protein and kinase activity

scientific article published on July 1986

Dyskerin Mutations Present in Dyskeratosis Congenita Patients Increase Oxidative Stress and DNA Damage Signalling in Dictyostelium Discoideum

scientific article published on 08 November 2019

Expression of actin isoforms in Artemia

scientific article published in January 1992

Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells.

scientific article

Functional genomics in Dictyostelium: MidA, a new conserved protein, is required for mitochondrial function and development

scientific article published on 28 February 2006

GSE4, a Small Dyskerin- and GSE24.2-Related Peptide, Induces Telomerase Activity, Cell Proliferation and Reduces DNA Damage, Oxidative Stress and Cell Senescence in Dyskerin Mutant Cells

scientific article published on 16 November 2015

Gene expression after resumption of development of Artemia franciscana cryptobiotic embryos.

scientific article published in March 1994

Genetic analyses of aplastic anemia and idiopathic pulmonary fibrosis patients with short telomeres, possible implication of DNA-repair genes

article

High DNA sequence variability at the alpha 1 Na/K-ATPase locus of Artemia franciscana (brine shrimp): polymorphism in a gene for salt-resistance in a salt-resistant organism

scientific article

High resolution melting analysis for the identification of novel mutations in DKC1 and TERT genes in patients with dyskeratosis congenita.

scientific article published on 2 June 2012

Identification of an Artemia franciscana retropseudogene containing part of the last exons of the sarco/endoplasmic reticulum Ca-ATPase-encoding SERCA gene.

scientific article published on November 1994

Identification of genes dependent on the MADS box transcription factor SrfA in Dictyostelium discoideum development

scientific article published on April 2004

In situ hybridization analyses of Na, K-ATPase alpha-subunit expression during early larval development of Artemia franciscana

scientific article published on 01 April 1995

In vitro polyadenylation of messenger ribonucleoprotein particles stored in Artemia dormant embryos

scientific article published on 01 October 1982

Investigating gene expression: in situ hybridization and reporter genes.

scientific article published in January 2006

Isolation and characterization of the gene coding for Artemia franciscana TATA-binding protein: expression in cryptobiotic and developing embryos.

scientific article

Isolation of cDNA clones coding for mitochondrial 16S ribosomal RNA from the crustacean Artemia

scientific article published in September 1988

Mef2A, a homologue of animal Mef2 transcription factors, regulates cell differentiation in Dictyostelium discoideum

scientific article

Molecular cloning and expression of four actin isoforms during Artemia development.

scientific article published on September 1990

Molecular systematics of dictyostelids: 5.8S ribosomal DNA and internal transcribed spacer region analyses

scientific article

Mutations in XLF/NHEJ1/Cernunnos gene results in downregulation of telomerase genes expression and telomere shortening

scientific article published on 24 March 2017

New DNA sequencing technologies open a promising era for cancer research and treatment

scientific article published on May 2011

Overexpression of the multidrug efflux pump SmeDEF impairs Stenotrophomonas maltophilia physiology.

scientific article

Polymorphism and structure of the gene coding for the alpha 1 subunit of the Artemia franciscana Na/K-ATPase

scientific article published on January 1997

Purification and properties of cAMP-independent nuclear protein kinase from Dictyostelium discoideum

scientific article published on 01 April 1984

Purification and subunit structure of RNA polymerases I and II from Dictyostelium discoideum vegetative cells

scientific article published on 01 February 1985

Regulated expression of the MADS-box transcription factor SrfA mediates activation of gene expression by protein kinase A during Dictyostelium sporulation.

scientific article published in September 2002

Regulation of promoter occupancy during activation of cryptobiotic embryos from the crustacean Artemia franciscana.

scientific article

Role of Dusp6 Phosphatase as a Tumor Suppressor in Non-Small Cell Lung Cancer

scientific article published on 25 April 2019

Role of SP65 in assembly of the Dictyostelium discoideum spore coat

scientific article

Similar alternative splicing events generate two sarcoplasmic or endoplasmic reticulum Ca-ATPase isoforms in the crustacean Artemia franciscana and in vertebrates

scientific article published on July 1993

SrfB, a member of the Serum Response Factor family of transcription factors, regulates starvation response and early development in Dictyostelium.

scientific article published on 31 January 2008

Structural and functional studies of a family of Dictyostelium discoideum developmentally regulated, prestalk genes coding for small proteins.

scientific article

Structure of Artemia franciscana sarco/endoplasmic reticulum Ca-ATPase gene.

scientific article published in April 1994

Structure of Dictyostelium discoideum telomeres. Analysis of possible replication mechanisms

scientific article published on 24 September 2019

The Dictyostelium discoideum acaA gene is transcribed from alternative promoters during aggregation and multicellular development

scientific article

The LFA-1, Mac-1 leucocyte adhesion glycoprotein family and its deficiency in a heritable human disease

scientific article published on 01 February 1985

The MADS-box gene srfA is expressed in a complex pattern under the control of alternative promoters and is essential for different aspects of Dictyostelium development

scientific article

The MADS-box transcription factor SrfA is required for actin cytoskeleton organization and spore coat stability during Dictyostelium sporulation

scientific article published on 01 January 2004

The dual-specificity protein phosphatase MkpB, homologous to mammalian MKP phosphatases, is required for D. discoideum post-aggregative development and cisplatin response.

scientific article published in March 2011

The mouse leukocyte adhesion proteins Mac-1 and LFA-1: studies on mRNA translation and protein glycosylation with emphasis on Mac-1

scientific article published on 01 August 1986

Tissue-specific alternative promoters regulate the expression of the two sarco/endoplasmic reticulum Ca-ATPase isoforms from Artemia franciscana

scientific article

Tissue-specific expression of two Artemia franciscana sarco/endoplasmic reticulum Ca-ATPase isoforms

scientific article published on 01 April 1996

Transactivation domains are not functionally conserved between vertebrate and invertebrate serum response factors.

scientific article published in August 2002

Transcriptional regulation during the activation and development of Artemia franciscana encysted embryos.

scientific article

cAMP and DIF-1 repress the expression of the Dictyostelium MADS-box gene srfA at early stages of development.

scientific article published in July 2001