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List of works by John G Clohessy

A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer

scientific article published on 2 June 2013

A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis

scientific article

An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance.

scientific article published in April 2018

An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.

scientific article published on 15 January 2018

Author Correction: A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer

scientific article published on 03 September 2020

Author Correction: Intragenic antagonistic roles of protein and circRNA in tumorigenesis

scientific article published on 01 February 2020

Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity

scientific article published on 8 March 2017

Cabozantinib unlocks efficient in vivo targeted delivery of neutrophil-loaded nanoparticles into murine prostate tumors

scientific article published on 04 December 2020

Characterization and analysis of the composition and dynamics of the mammalian riboproteome.

scientific article published on 19 September 2013

Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism.

scientific article published on 15 January 2018

Differential expression of S6K2 dictates tissue-specific requirement for S6K1 in mediating aberrant mTORC1 signaling and tumorigenesis.

scientific article

Differential requirement of mTOR in postmitotic tissues and tumorigenesis

scientific article

Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms

scientific article published on 8 January 2018

Dual DNA and protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia

scientific article published on 01 March 2021

Dyskerin expression influences the level of ribosomal RNA pseudo-uridylation and telomerase RNA component in human breast cancer.

scientific article published on September 2006

Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non-small cell lung cancer

scientific article published on 15 February 2018

Found in translation of mTOR signaling.

scientific article published on 29 May 2012

Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita

scientific article published on 30 September 2019

Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer

scientific article published on 14 April 2021

In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at Endosomes

scientific article published on 16 April 2015

Intragenic antagonistic roles of protein and circRNA in tumorigenesis

scientific article published on 17 June 2019

Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis

scientific article published on 27 December 2005

Mouse hospital and co-clinical trial project--from bench to bedside.

scientific article published on 21 April 2015

NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease

scientific article published on 29 October 2013

Nanoformulation of Olaparib Amplifies PARP Inhibition and Sensitizes PTEN/TP53-Deficient Prostate Cancer to Radiation

scientific article published on 12 May 2017

Npm1 is a haploinsufficient suppressor of myeloid and lymphoid malignancies in the mouse

scientific article published on 22 January 2008

Of model pets and cancer models: an introduction to mouse models of cancer

scientific article published on 01 January 2014

Optimized RNA-targeting CRISPR/Cas13d technology outperforms shRNA in identifying functional circRNAs

scientific article published on 21 January 2021

PI3K drives the de novo synthesis of coenzyme A from vitamin B5

scientific article published on 27 July 2022

Pro-senescence therapy for cancer treatment

scientific article published on 24 June 2011

Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway

scientific article published on 01 May 2019

Role of BRAFV600E in the first preclinical model of multifocal infiltrating myopericytoma development and microenvironment

scientific article

Role of aberrant PI3K pathway activation in gallbladder tumorigenesis

scientific article published on February 2014

SPAR, a lncRNA encoded mTORC1 inhibitor.

scientific article published on 20 March 2017

Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.

scientific article published on April 2016

Subtle variations in Pten dose determine cancer susceptibility

scientific article

The Mouse Hospital and Its Integration in Ultra-Precision Approaches to Cancer Care

The RNA binding protein ESRP1 fine-tunes the expression of pluripotency-related factors in mouse embryonic stem cells

scientific article

The Tug1 lncRNA locus is essential for male fertility

scientific article published on 07 September 2020

The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model

scientific article

The leukemia-associated cytoplasmic nucleophosmin mutant is an oncogene with paradoxical functions: Arf inactivation and induction of cellular senescence.

scientific article published on 4 June 2007

The pleiotropic role of non-coding genes in development and cancer.

scientific article published on 16 November 2016

Vulnerabilities in mIDH2 AML confer sensitivity to APL-like targeted combination therapy

scientific article published on 25 April 2019

Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition.

scientific article

beta-tting on p63 as a metastatic suppressor

scientific article published in April 2009

mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide

scientific journal article

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