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List of works by Douglas A Gray

A Unifying Hypothesis for Familial and Sporadic Alzheimer's Disease

scientific article published on February 14, 2012

A new biogerontology lab in newcastle

scientific article published on 23 February 2005

A ubiquitin-specific protease that efficiently cleaves the ubiquitin-proline bond.

scientific article published in December 1997

Activation of int-1 and int-2 loci in GRf mammary tumors

scientific article published on 01 October 1986

Activation of p38MAPK contributes to expanded polyglutamine-induced cytotoxicity.

scientific article

An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline

scientific article

Bone marrow-derived stem cells initiate pancreatic regeneration.

scientific article

Cisplatin induces p53-dependent FLICE-like inhibitory protein ubiquitination in ovarian cancer cells.

scientific article

Coordination of glioblastoma cell motility by PKCι

scientific article

Damage control--a possible non-proteolytic role for ubiquitin in limiting neurodegeneration.

scientific article

Delayed spinocerebellar ataxia in transgenic mice expressing mutant ubiquitin.

scientific article published in February 2006

Depletion of Beta Cell Intranuclear Rodlets in Human Type II Diabetes.

scientific article published on 2 August 2017

Deubiquitinating Enzymes in Model Systems and Therapy: Redundancy and Compensation Have Implications

scientific article published on 23 September 2019

Effect of ubiquitin expression on neuropathogenesis in a mouse model of familial amyotrophic lateral sclerosis

scientific article published on 01 February 2005

Effects of mutant ubiquitin on ts1 retrovirus-mediated neuropathology.

scientific article

Engineering PTEN-L for Cell-Mediated Delivery.

scientific article published on 21 November 2017

Evolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11

scientific article

Experimental and computational analysis of polyglutamine-mediated cytotoxicity

scientific article

Explaining oscillations and variability in the p53-Mdm2 system

scientific article

FUS-immunoreactive intranuclear inclusions in neurodegenerative disease.

scientific article published on 21 September 2009

GSK3 and p53 - is there a link in Alzheimer's disease?

scientific article

Genomic structure of Unp, a murine gene encoding a ubiquitin-specific protease.

scientific article

Hyperfiltration in ubiquitin C-terminal hydrolase L1-deleted mice

scientific article published on 18 July 2018

Insertional mutagenesis: neoplasia arising from retroviral integration.

scientific article published on January 1991

Intranuclear rodlets in the substantia nigra: interactions with marinesco bodies, ubiquitin, and promyelocytic leukemia protein

scientific article published on 01 November 2004

Investigating interventions in Alzheimer's disease with computer simulation models

scientific article

Maneuvering for advantage: the genetics of mouse susceptibility to virus infection.

scientific article

Meeting report: 4th European Congress of Biogerontology

scientific article published on 23 February 2005

Metformin Abrogates Age-Associated Ovarian Fibrosis

scientific article published on 09 October 2019

Mouse mammary tumor virus DNA sequences in tumorigenic and nontumorigenic cells from a mammary adenocarcinoma

scientific article published on April 15, 1982

NF-κB activation and polyubiquitin conjugation are required for pulmonary inflammation-induced diaphragm atrophy

scientific article published on 14 October 2011

Protection against murine osteoarthritis by inhibition of the 26S proteasome and lysine-48 linked ubiquitination.

scientific article published on 8 April 2014

Regulation of PCNA polyubiquitination in human cells

scientific article

Replication of a Moloney murine leukemia virus mutant lacking the ELP binding site.

scientific article published on August 1994

Reversible modulation of SIRT1 activity in a mouse strain

scientific article

SENS and the polarization of aging-related research

scientific article published on 01 March 2006

SIRT1 is a Highly Networked Protein That Mediates the Adaptation to Chronic Physiological Stress.

scientific article published on March 2013

Selection preserves Ubiquitin Specific Protease 4 alternative exon skipping in therian mammals.

scientific article published on 2 February 2016

Stimulation of the murine Uchl1 gene promoter by the B-Myb transcription factor

scientific article published on 01 October 2003

Structural disorder and the loss of RNA homeostasis in aging and neurodegenerative disease.

scientific article published on 14 August 2013

Transgenic mouse model of kidney disease: Insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome

scientific article published on August 10, 1990

Ubiquitin C-terminal hydrolase 1: A novel functional marker for liver myofibroblasts and a therapeutic target in chronic liver disease

scientific article published on 8 August 2015

Ubiquitin C-terminal hydrolase L1 deletion ameliorates glomerular injury in mice with ACTN4-associated focal segmental glomerulosclerosis

scientific article published on 22 March 2014

Ubiquitin COOH-terminal hydrolase L1 deletion is associated with urinary α-klotho deficiency and perturbed phosphate homeostasis

scientific article published on 18 April 2018

What deubiquitinating enzymes, oncogenes, and tumor suppressors actually do: Are current assumptions supported by patient outcomes?

scientific article published on 07 January 2021

hMMS2 serves a redundant role in human PCNA polyubiquitination

scientific article