List of works - Christian Cole

14-3-3-Pred: improved methods to predict 14-3-3-binding phosphopeptides

scientific article

3-substituted-5-aziridinyl-1-methylindole-4,7-diones as NQO1-directed antitumour agents: mechanism of activation and cytotoxicity in vitro.

scientific article published on October 2003

A Dictyostelium SH2 adaptor protein required for correct DIF-1 signaling and pattern formation

scientific article published on 21 March 2011

A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study

scientific article published in 2022

A National Network of Safe Havens: Scottish Perspective

scientific article published on 09 March 2022

A Proteomic Approach to Analyze the Aspirin-mediated Lysine Acetylome

scientific article (publication date: February 2017)

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d

scientific article published on 29 November 2016

Adenylate cyclase A acting on PKA mediates induction of stalk formation by cyclic diguanylate at the Dictyostelium organizer

scientific article published on 05 January 2017

AlmostSignificant: Simplifying quality control of high-throughput sequencing data

scholarly article published 16 May 2016

AlmostSignificant: simplifying quality control of high-throughput sequencing data

scientific article

Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.

scientific article published in January 2005

Creation of a universal experimental protocol for the investigation of transfer and persistence of trace evidence: Part 1 - From design to implementation for particulate evidence

scientific article published on 29 August 2021

Direct sequencing of Arabidopsis thaliana RNA reveals patterns of cleavage and polyadenylation.

scientific article published on 22 July 2012

EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis

scientific article published on 31 May 2019

Expanding the Phenotypic Spectrum of Olmsted Syndrome

scientific article published on 12 June 2015

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

scientific article

Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs

scientific article

Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma.

scientific article published on 14 October 2012

How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?

scientific article

Human Missense Variation is Constrained by Domain Structure and Highlights Functional and Pathogenic Residues

scholarly article published 12 April 2017

Improved annotation of 3' untranslated regions and complex loci by combination of strand-specific direct RNA sequencing, RNA-Seq and ESTs.

scientific article

Improved annotation with de novo transcriptome assembly in four social amoeba species.

scientific article

Isolated recessive nail dysplasia caused by FZD6 mutations: report of three families and review of the literature.

scientific article

JPred4: a protein secondary structure prediction server

scientific article

Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy

scientific article published on 11 January 2016

Loss-of-function mutations in CAST cause peeling skin, leukonychia, acral punctate keratoses, cheilitis, and knuckle pads.

scientific article

Machine learning models in trusted research environments -- understanding operational risks

scientific article published on 14 December 2023

Mutations in POGLUT1 in Galli-Galli/Dowling-Degos disease.

scientific article published on August 2016

Mutations in desmoglein 1 cause diverse inherited palmoplantar keratoderma phenotypes: implications for genetic screening

scientific article published on 18 August 2016

Novel autosomal dominant mutation in loricrin presenting as prominent ichthyosis.

scientific article published on 12 May 2015

Potential tumor-selective nitroimidazolylmethyluracil prodrug derivatives: inhibitors of the angiogenic enzyme thymidine phosphorylase.

scientific article

Proteus: an R package for downstream analysis of MaxQuant output

article

Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins

scientific article

Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin

scientific article

Side-chain conformational entropy at protein-protein interfaces.

scientific article

Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment

scientific article published on 23 July 2015

System-wide changes to SUMO modifications in response to heat shock

scientific article

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

scientific journal article

Transcription termination and chimeric RNA formation controlled by Arabidopsis thaliana FPA.

scientific article

List of works by Christian Cole

14-3-3-Pred: improved methods to predict 14-3-3-binding phosphopeptides

3-substituted-5-aziridinyl-1-methylindole-4,7-diones as NQO1-directed antitumour agents: mechanism of activation and cytotoxicity in vitro.

A Dictyostelium SH2 adaptor protein required for correct DIF-1 signaling and pattern formation

A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study

A National Network of Safe Havens: Scottish Perspective

A Proteomic Approach to Analyze the Aspirin-mediated Lysine Acetylome

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d

Adenylate cyclase A acting on PKA mediates induction of stalk formation by cyclic diguanylate at the Dictyostelium organizer

AlmostSignificant: Simplifying quality control of high-throughput sequencing data

AlmostSignificant: simplifying quality control of high-throughput sequencing data

Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.

Creation of a universal experimental protocol for the investigation of transfer and persistence of trace evidence: Part 1 - From design to implementation for particulate evidence

Direct sequencing of Arabidopsis thaliana RNA reveals patterns of cleavage and polyadenylation.

EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis

Expanding the Phenotypic Spectrum of Olmsted Syndrome

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs

Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma.

How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?

Human Missense Variation is Constrained by Domain Structure and Highlights Functional and Pathogenic Residues

Improved annotation of 3' untranslated regions and complex loci by combination of strand-specific direct RNA sequencing, RNA-Seq and ESTs.

Improved annotation with de novo transcriptome assembly in four social amoeba species.

Isolated recessive nail dysplasia caused by FZD6 mutations: report of three families and review of the literature.

JPred4: a protein secondary structure prediction server

Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy

Loss-of-function mutations in CAST cause peeling skin, leukonychia, acral punctate keratoses, cheilitis, and knuckle pads.

Machine learning models in trusted research environments -- understanding operational risks

Mutations in POGLUT1 in Galli-Galli/Dowling-Degos disease.

Mutations in desmoglein 1 cause diverse inherited palmoplantar keratoderma phenotypes: implications for genetic screening

Novel autosomal dominant mutation in loricrin presenting as prominent ichthyosis.

Potential tumor-selective nitroimidazolylmethyluracil prodrug derivatives: inhibitors of the angiogenic enzyme thymidine phosphorylase.

Proteus: an R package for downstream analysis of MaxQuant output

Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins

Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin

Side-chain conformational entropy at protein-protein interfaces.

Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment

System-wide changes to SUMO modifications in response to heat shock

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

Transcription termination and chimeric RNA formation controlled by Arabidopsis thaliana FPA.