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List of works by Jörg Menche

A DIseAse MOdule Detection (DIAMOnD) algorithm derived from a systematic analysis of connectivity patterns of disease proteins in the human interactome

scientific article (publication date: April 2015)

A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor

scientific article published on 22 May 2017

A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease

scientific article

A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma

scientific article published on 12 January 2015

A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection

scientific article published on 5 February 2018

A proteome-scale map of the human interactome network

scientific article

A systems biology approach to cGMP suggests a prominent role for sGC in stroke: Validation by mechanism-based activation of apo-sGC in non-steal dosing coveys neuroprotection and increased survival

scientific article

An inter-species protein-protein interaction network across vast evolutionary distance

scientific article (publication date: 22 April 2016)

Asymptotic properties of degree-correlated scale-free networks

scientific article published on 9 April 2010

BAFF Neutralization Aggravates Atherosclerosis

BioProfiling.jl: profiling biological perturbations with high-content imaging in single cells and heterogeneous populations

scientific article published in 2021

Canonical genetic signatures of the adult human brain

scientific article

Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein

scientific article published on 20 December 2017

Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.

scientific article

Disease networks. Uncovering disease-disease relationships through the incomplete interactome

scientific article published on February 2015

Endophenotype Network Models: Common Core of Complex Diseases

scientific article published on 09 June 2016

Environmental arginine controls multinuclear giant cell metabolism and formation

scientific article published on 22 January 2020

From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration

scientific article

Germline biallelic PIK3CG mutations in a multifaceted immunodeficiency with immune dysregulation

scientific article published on 30 January 2020

HACE1 deficiency leads to structural and functional neurodevelopmental defects

scientific article published on 29 April 2019

Human symptoms-disease network

scientific article published on 26 June 2014

Hydrothermal polymerization of porous aromatic polyimide networks and machine learning-assisted computational morphology evolution interpretation

scientific article published on 08 September 2021

Integrating personalized gene expression profiles into predictive disease-associated gene pools

scientific article

Integration of Molecular Interactome and Targeted Interaction Analysis to Identify a COPD Disease Network Module

scientific article published in Scientific Reports

MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation

scientific article published on 27 May 2019

Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48.

scientific article published on 11 June 2018

Mapping the Human Kinome in Response to DNA Damage

scientific article published on 01 January 2019

Mapping the perturbome network of cellular perturbations

scientific article published on 13 November 2019

Mutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasms

scientific article published on 07 May 2019

Network Approaches for Charting the Transcriptomic and Epigenetic Landscape of the Developmental Origins of Health and Disease

publication published on 26 April 2022

Network analysis reveals rare disease signatures across multiple levels of biological organization

scientific article published on 09 November 2021

Network medicine: a new paradigm for cardiovascular disease research and beyond

scientific article published in August 2017

Network-based analysis of genome wide association data provides novel candidate genes for lipid and lipoprotein traits

scientific article

Network-based in silico drug efficacy screening

scientific article

Non-classical monocytes as mediators of tissue destruction in arthritis

scientific article published on 29 June 2018

Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia

scientific article published in November 2017

Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation

scientific article published on 01 August 2019

Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology

scholarly article by Joaquim Aguirre-Plans et al published 22 June 2018 in Pharmaceuticals

Quantifying a certain ''advantage law'': minority game with above the rules agents

Sequences of phase transitions in Ising models on correlated networks ⬇️

scientific article published on June 20, 2011

Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers

scientific article published on 19 August 2019

Systems Medicine: from molecular features and models to the clinic in COPD.

scientific article published on 28 November 2014

The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages

scientific article published on 16 November 2020

The VRNetzer platform enables interactive network analysis in Virtual Reality

scientific article published on 23 April 2021

The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity

scientific article published on 01 July 2020

The immune system as a social network

scientific article published in April 2017

Tissue Specificity of Human Disease Module

scientific article published on 17 October 2016

Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function

scientific article published on 26 November 2019

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