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List of works by Fabrice Lejeune

2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations

scientific article published on 20 March 2020

Alternative splicing of intron 3 of the serine/arginine-rich protein 9G8 gene. Identification of flanking exonic splicing enhancers and involvement of 9G8 as a trans-acting factor

scientific article (publication date: 16 March 2001)

Broad specificity of SR (serine/arginine) proteins in the regulation of alternative splicing of pre-messenger RNA.

scientific article published on January 2004

CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells

scientific article published on 25 September 2005

Caspases shutdown nonsense-mediated mRNA decay during apoptosis

scientific article

Deciphering the molecular mechanism of stop codon readthrough

scientific article published on 22 October 2020

Evidence that poly(A) binding protein C1 binds nuclear pre-mRNA poly(A) tails

scientific article

Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-{beta}.

scientific article published on January 2010

Immunopurification and analysis of protein and RNA components of mRNP in mammalian cells

scientific article published in January 2004

Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies

scientific article

Major source of antigenic peptides for the MHC class I pathway is produced during the pioneer round of mRNA translation

scientific article

Mechanistic links between nonsense-mediated mRNA decay and pre-mRNA splicing in mammalian cells

scientific article

Nonsense-mediated mRNA decay at the crossroads of many cellular pathways

scientific article published on 24 January 2017

Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities

scientific article (publication date: September 2003)

Optimized approach for the identification of highly efficient correctors of nonsense mutations in human diseases

scientific article

Premature termination codon readthrough in human cells occurs in novel cytoplasmic foci and requires UPF proteins

scientific article

RNA Processing and Human Disorders

Rescue of nonsense mutations by amlexanox in human cells

scientific article published on 31 August 2012

TIA-1 and TIAR activate splicing of alternative exons with weak 5' splice sites followed by a U-rich stretch on their own pre-mRNAs

scientific article (publication date: 2 November 2001)

Targeting nonsense-mediated mRNA decay in colorectal cancers with microsatellite instability

scientific article published on 19 September 2018

The CD44 alternative v9 exon contains a splicing enhancer responsive to the SR proteins 9G8, ASF/SF2, and SRp20.

scientific article

The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling

scientific article

The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells

scientific article

The pioneer translation initiation complex is functionally distinct from but structurally overlaps with the steady-state translation initiation complex

scientific article

UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation

scientific article

eIF4G is required for the pioneer round of translation in mammalian cells

scientific article

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