Search filters

List of works by José Antonio Rodríguez

A cellular reporter to evaluate CRM1 nuclear export activity: functional analysis of the cancer-related mutant E571K.

scientific article published on 16 June 2016

A global survey of CRM1-dependent nuclear export sequences in the human deubiquitinase family.

scientific article published in January 2012

A short in-frame deletion in NTRK1 tyrosine kinase domain caused by a novel splice site mutation in a patient with congenital insensitivity to pain with anhidrosis ⬇️

scientific article published on June 27, 2011

Absence of COCH gene mutations in patients with superior semicircular canal dehiscence

scientific article published on 02 December 2011

Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis

scientific article published on 08 July 2019

BARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent BRCA1 nuclear import and inhibiting BRCA1 nuclear export

scientific article (publication date: 14 June 2002)

Bortezomib, but not cisplatin, induces mitochondria-dependent apoptosis accompanied by up-regulation of noxa in the non-small cell lung cancer cell line NCI-H460.

scientific article published on March 2007

CRM1-mediated nuclear export determines the cytoplasmic localization of the antiapoptotic protein Survivin

scientific article published on 01 April 2002

Cathepsin B mediates caspase-independent cell death induced by microtubule stabilizing agents in non-small cell lung cancer cells.

scientific article

Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells.

scientific article

Conformational stabilization as a strategy to prevent nucleophosmin mislocalization in leukemia

scientific article published on 24 October 2017

Cytoplasmic mislocalization of BRCA1 caused by cancer-associated mutations in the BRCT domain.

scientific article published on February 2004

Definition of a region of loss of heterozygosity at chromosome 11q in cervical carcinoma

scientific article published on 01 June 1999

Description of USP12 nuclear export sequence

scientific article published on 2 June 2016

Detailed Dissection of UBE3A-Mediated DDI1 Ubiquitination

scientific article published on 03 May 2019

E2F2 and CREB cooperatively regulate transcriptional activity of cell cycle genes

scientific article published on 12 September 2013

Enhanced cytotoxicity induced by gefitinib and specific inhibitors of the Ras or phosphatidyl inositol-3 kinase pathways in non-small cell lung cancer cells.

scientific article published on January 2006

Enhancing prediction of short linear protein motifs with Wregex 3.0

scientific article published in 2024

Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study

scientific article published on 01 October 2006

Expression and localization of inhibitor of apoptosis proteins in normal human tissues

scientific article published on 17 November 2005

Frequent overexpression of aurora B kinase, a novel drug target, in non-small cell lung carcinoma patients

scientific article published on 01 November 2006

Genotype analysis of the VNTR polymorphism in the SMYD3 histone methyltransferase gene: lack of correlation with the level of histone H3 methylation in NSCLC tissues or with the risk of NSCLC

scientific article published on 01 March 2008

Global histone modifications predict prognosis of resected non small-cell lung cancer.

scientific article

Homodimerization antagonizes nuclear export of survivin

scientific article published on 20 August 2007

Identification of multiple nuclear export sequences in Fanconi anemia group A protein that contribute to CRM1-dependent nuclear export.

scientific article

Immunohistochemical detection of nuclear survivin in NSCLC: a comparison of commercial antibodies

scientific article published on 01 April 2007

Immunohistochemical expression of mdm2 and p21WAF1 in invasive cervical cancer: correlation with p53 protein and high risk HPV infection

scientific article published on October 1998

Interplay between nuclear transport and ubiquitin/SUMO modifications in the regulation of cancer-related proteins.

scientific article published on 03 April 2014

Kahalalide F induces necrosis-like cell death that involves depletion of ErbB3 and inhibition of Akt signaling.

scientific article

Keynote comment: are large-scale cancer-genomics projects ready to use?

scientific article published on 01 March 2006

Leukemia-Associated Mutations in Nucleophosmin Alter Recognition by CRM1: Molecular Basis of Aberrant Transport

scientific article published on 19 June 2015

Low incidence of microsatellite instability in patients with cervical carcinomas.

scientific article published in October 1998

Molecular Pathways: Anticancer Activity by Inhibition of Nucleocytoplasmic Shuttling

scientific article published on 31 August 2015

Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells.

scientific article published on 10 January 2008

Mutations in the 'Fingers' subdomain of the deubiquitinase USP1 modulate its function and activity

scientific article

Nuclear localization of survivin is a positive prognostic factor for survival in advanced non-small-cell lung cancer

scientific article published on 01 November 2004

Nuclear shuttling and TRAF2-mediated retention in the cytoplasm regulate the subcellular localization of cIAP1 and cIAP2.

scientific article published on August 2004

Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients.

scientific article published on April 2006

Production and evaluation of alloantibodies against sheep MHC Class I antigens.

scientific article published on March 2004

Proteome-wide search for functional motifs altered in tumors: Prediction of nuclear export signals inactivated by cancer-related mutations

scientific article

Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation.

scientific article published on 29 December 2006

Structure-function analysis of USP1: insights into the role of Ser313 phosphorylation site and the effect of cancer-associated mutations on autocleavage.

scientific article

Subcellular localization of CrmA: identification of a novel leucine-rich nuclear export signal conserved in anti-apoptotic serpins.

scientific article

TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells

scientific article

The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma

scientific article published on 11 February 2021

The nuclear protein ALY binds to and modulates the activity of transcription factor E2F2.

scientific article published on 7 January 2013

Therapeutic Effects of XPO1 Inhibition in Thymic Epithelial Tumors

scientific article published on 17 August 2017

Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.

scientific article published in February 2018

Two nuclear localization signals in USP1 mediate nuclear import of the USP1/UAF1 complex

scientific article

USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy ⬇️

scientific article published on August 10, 2013

Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeres

scientific article

WDR20 regulates shuttling of the USP12 deubiquitinase complex between the plasma membrane, cytoplasm and nucleus

scientific article published on 03 November 2018

Paulina is supported by:

About Paulina

Help