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List of works by Stian Knappskog

A novel type of deletion in the CDKN2A gene identified in a melanoma-prone family

scientific article published on December 2006

APOBEC3A/B deletion polymorphism and cancer risk

scientific article published on 13 November 2017

Activation of Akt characterizes estrogen receptor positive human breast cancers which respond to anthracyclines

scientific article published on 17 April 2017

Adjuvant treatment: the contribution of expression microarrays

scientific article

Alterations in the p53 pathway and p16INK4a expression predict overall survival in metastatic melanoma patients treated with dacarbazine

scientific article published on 27 May 2010

Alterations of the retinoblastoma gene in metastatic breast cancer

scientific article

Assessment of tumor suppressor promoter methylation in healthy individuals

scientific article published on 28 August 2020

Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer

scientific article

Associations between the MDM2 promoter P1 polymorphism del1518 (rs3730485) and incidence of cancer of the breast, lung, colon and prostate

scientific article published on 12 April 2016

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences

scientific article published on 01 February 2019

BRCA1 methylation in newborns: genetic disposition, maternal transfer, environmental influence, or by chance only?

scientific article published on 22 October 2018

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

scientific article published on 26 September 2016

Breast cancer prognostication and prediction in the postgenomic era.

scientific article published on 21 February 2007

CHEK2 mutations affecting kinase activity together with mutations in TP53 indicate a functional pathway associated with resistance to epirubicin in primary breast cancer

scientific article

CXXC5 (retinoid-inducible nuclear factor, RINF) is a potential therapeutic target in high-risk human acute myeloid leukemia

scientific article published on September 2013

Chemosensitivity and p53; new tricks by an old dog ⬇️

scientific article published on November 6, 2012

Clinical effect of temozolomide-based chemotherapy in poorly differentiated endocrine carcinoma after progression on first-line chemotherapy

scientific article published on 31 March 2011

Concomitant inactivation of the p53- and pRB- functional pathways predicts resistance to DNA damaging drugs in breast cancer in vivo

scientific article

Constitutional Mosaic Epimutations - a hidden cause of cancer?

scientific article published on 22 March 2019

Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia

scientific article

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

scientific article published on May 2016

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

scientific article published on 10 June 2016

Effect of CYP19 rs6493497 and rs7176005 haplotype status on in vivo aromatase transcription, plasma and tissue estrogen levels in postmenopausal women

scientific article published on 16 September 2011

Effect of the MDM2 promoter polymorphisms SNP309T>G and SNP285G>C on the risk of ovarian cancer in BRCA1 mutation carriers

scientific article

Effective Treatment of Metastatic Melanoma by Combining MAPK and PI3K Signaling Pathway Inhibitors ⬇️

scientific article published on 29 August 2019

Effects of SNP variants in the 17β-HSD2 and 17β-HSD7 genes and 17β-HSD7 copy number on gene transcript and estradiol levels in breast cancer tissue

scientific article

Effects of concomitant inactivation of p53 and pRb on response to doxorubicin treatment in breast cancer cell lines

scientific article published on 22 May 2017

Effects of theMDM2promoter SNP285 and SNP309 on Sp1 transcription factor binding and cancer risk ⬇️

scientific article published on September 1, 2011

Elevated levels of the steroidogenic factor 1 are associated with over-expression of CYP19 in an oestrogen-producing testicular Leydig cell tumour

scientific article published on February 2012

Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC.

scientific article published in June 2019

Erratum: Corrigendum: Signatures of mutational processes in human cancer

scientific article published in Nature

Estrogens Correlate with PELP1 Expression in ER Positive Breast Cancer

scientific article published on 6 August 2015

Exploring breast cancer estrogen disposition: the basis for endocrine manipulation

scientific article published on 26 July 2011

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

scientific article published on 11 May 2015

Functional characterisation of p53 mutants identified in breast cancers with suboptimal responses to anthracyclines or mitomycin

scientific article published on March 2013

Gene expression profiling-based identification of molecular subtypes in stage IV melanomas with different clinical outcome

scientific article published on 11 May 2010

Genomic Evolution of Breast Cancer Metastasis and Relapse

scientific article published on August 2017

Golgi-localized PAQR4 mediates Anti-apoptotic Ceramidase Activity in Breast Cancer

scientific article published on 14 April 2020

High PTEN gene expression is a negative prognostic marker in human primary breast cancers with preserved p53 function

scientific article published on 17 February 2017

High expression of the p53 isoform γ is associated with reduced progression-free survival in uterine serous carcinoma

scientific article

Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers

scientific article

Impact of KRAS, BRAF, PIK3CA, TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastases

scientific article published on 16 March 2016

Impact of the MDM2 splice-variants MDM2-A, MDM2-B and MDM2-C on cytotoxic stress response in breast cancer cells

scientific article

Influence of MDM2 SNP309 and SNP285 status on the risk of cancer in the breast, prostate, lung and colon

scientific article published on 10 December 2014

Influence of p53 Isoform Expression on Survival in High-Grade Serous Ovarian Cancers

article published in 2019

Intra-patient Inter-metastatic Genetic Heterogeneity in Colorectal Cancer as a Key Determinant of Survival after Curative Liver Resection.

scientific article

Introducing nano-scale quantitative polymerase chain reaction

scientific article published on 02 November 2018

Inverse regulation of EGFR/HER1 and HER2-4 in normal and malignant human breast tissue

scientific article

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

scientific article

Low BRAF and NRAS expression levels are associated with clinical benefit from DTIC therapy and prognosis in metastatic melanoma

scientific article published on 15 May 2013

Low expression levels of ATM may substitute for CHEK2 /TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer

scientific article

MDM2 SNP309 and risk of cervical cancer

scientific article published on 17 April 2014

MDM2 SNP309 and risk of endometrial cancer

scientific article published in April 2013

MDM2 SNP309 and risk of endometrial cancer

scientific article published on 26 June 2014

MDM2 promoter SNP344T>A (rs1196333) status does not affect cancer risk

scientific article

MDM2 promoter SNP55 (rs2870820) affects risk of colon cancer but not breast-, lung-, or prostate cancer

scientific article published on 14 September 2016

MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk

scientific article

MDM2promoter SNP285 and SNP309; phylogeny and impact on cancer risk ⬇️

scientific article published on March 1, 2011

MDM4 SNP34091 (rs4245739) and its effect on breast-, colon-, lung-, and prostate cancer risk

scientific article published on 16 October 2015

Mapping genetic alterations causing chemoresistance in cancer: identifying the roads by tracking the drivers ⬇️

scientific article published on March 11, 2013

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

scientific article

Mutation analysis by deep sequencing of pancreatic juice from patients with pancreatic ductal adenocarcinoma

Mutations and polymorphisms of the p21B transcript in breast cancer

scientific article published on August 2007

New doctorial cancer research: germline genetic alterations affecting CDKN2A, MDM2, and CDKN1A in melanoma and breast cancer patients

scientific article published on 01 December 2007

Outcome after surgery for primary hyperaldosteronism may depend on KCNJ5 tumor mutation status: a population-based study from Western Norway

scientific article published on 19 June 2013

P21/WAF1 mutation and drug resistance to paclitaxel in locally advanced breast cancer

scientific article published on 01 June 2007

P53 and its molecular basis to chemoresistance in breast cancer ⬇️

scientific article published on 08 February 2012

Patterns of genomic evolution in advanced melanoma

scientific article published on 10 July 2018

Performance comparison of three BRAF V600E detection methods in malignant melanoma and colorectal cancer specimens

scientific article

Population distribution and ancestry of the cancer protective MDM2 SNP285 (rs117039649).

scientific article

Predictive and prognostic impact of TP53 mutations and MDM2 promoter genotype in primary breast cancer patients treated with epirubicin or paclitaxel

scientific article

Prevalence of the CHEK2 R95* germline mutation ⬇️

scientific article published on 27 September 2016

Promoter SNPs rs116896264 and rs73933062 form a distinct haplotype and are associated with galectin-4 overexpression in colorectal cancer.

scientific article published on 16 December 2015

RINF (CXXC5) is overexpressed in solid tumors and is an unfavorable prognostic factor in breast cancer

scientific article published on 16 February 2011

Re: Murine double minute 2 promoter SNP309 polymorphism and prostate cancer risk: a meta-analysis

scientific article published on July 30, 2012

Recent data on intratumor estrogens in breast cancer

scientific article

SNP285C modulates oestrogen receptor/Sp1 binding to the MDM2 promoter and reduces the risk of endometrial but not prostatic cancer

scientific article published on 24 November 2011

Signatures of mutational processes in human cancer

scientific article (publication date: 22 August 2013)

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

scientific article

Spontaneous Malignant Transformation of Human Mesenchymal Stem Cells Reflects Cross-Contamination: Putting the Research Field on Track - Letter

scientific article published on 14 July 2010

Subclonal diversification of primary breast cancer revealed by multiregion sequencing

scientific article published on 22 June 2015

Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia.

scientific article

TP53 status predicts long-term survival in locally advanced breast cancer after primary chemotherapy

scientific article

The Functional Roles of the MDM2 Splice Variants P2-MDM2-10 and MDM2-∆5 in Breast Cancer Cells

scientific article published on 24 August 2017

The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians

article

The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian-but not endometrial cancer

scientific article published on 11 February 2016

The circular RNome of primary breast cancer

scientific article published on 28 January 2019

The level of synthesis and secretion of Gaussia princeps luciferase in transfected CHO cells is heavily dependent on the choice of signal peptide

scientific article published on 12 December 2006

The novel microRNAs hsa-miR-nov7 and hsa-miR-nov3 are over-expressed in locally advanced breast cancer

scientific article published on 16 April 2020

The novel p21 polymorphism p21G251A is associated with locally advanced breast cancer

scientific article published in October 2006

Treatment with aromatase inhibitors stimulates the expression of epidermal growth factor receptor-1 and neuregulin 1 in ER positive/HER-2/neu non-amplified primary breast cancers

scientific article published on 22 June 2016

Tumor cells interact with red blood cells via galectin-4 - a short report.

scientific article published on 14 March 2017

White Blood Cell BRCA1 Promoter Methylation Status and Ovarian Cancer Risk

scientific article published on 16 January 2018

ctDNA detected by ddPCR reveals changes in tumour load in metastatic malignant melanoma treated with bevacizumab

scientific article published on 25 November 2019

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