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List of works by Sebastian A. Leidel

A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis

scientific article published on December 2015

A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids

scientific article published on 03 November 2020

A novel translational control mechanism involving RNA structures within coding sequences.

scientific article published on 7 November 2016

Absolute Quantification of Noncoding RNA by Microscale Thermophoresis

scientific article published on 02 May 2019

An evolutionary approach uncovers a diverse response of tRNA 2-thiolation to elevated temperatures in yeast

scientific article published on 12 December 2014

Attomol-level quantification of chemically modified ribonucleosides enabled by capillary porous graphitic carbon columns in nano LC-MS

Centriolar SAS-5 is required for centrosome duplication in C. elegans

scientific article published in July 2004

Centrosome duplication and nematodes: recent insights from an old relationship

scientific article

Codon-specific translation reprogramming promotes resistance to targeted therapy

scientific article published in Nature

Differential Requirement for Translation Initiation Factor Pathways during Ecdysone-Dependent Neuronal Remodeling in Drosophila

scientific article published on 01 August 2018

Diversity of foliar endophytic ascomycetes in the endemic Corsican pine forests

scientific article published in 2018

Dual randomization of oligonucleotides to reduce the bias in ribosome-profiling libraries.

scientific article

Dynamic Regulation of tRNA Modifications in Cancer

Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer

scientific article published on 10 October 2016

Enzymatic or In Vivo Installation of Propargyl Groups in Combination with Click Chemistry for the Enrichment and Detection of Methyltransferase Target Sites in RNA

scientific article published on 22 March 2018

Enzymatischer oder In-vivo-Einbau von Propargylgruppen in Kombination mit Klick-Chemie zur Anreicherung und Detektion von Methyltransferase-Zielsequenzen in RNA

Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III

scientific article (publication date: 16 November 2000)

Glutaredoxin GRXS17 Associates with the Cytosolic Iron-Sulfur Cluster Assembly Pathway.

scientific article published on 8 August 2016

Innentitelbild: Enzymatischer oder In-vivo-Einbau von Propargylgruppen in Kombination mit Klick-Chemie zur Anreicherung und Detektion von Methyltransferase-Zielsequenzen in RNA (Angew. Chem. 21/2018)

Inside Cover: Enzymatic or In Vivo Installation of Propargyl Groups in Combination with Click Chemistry for the Enrichment and Detection of Methyltransferase Target Sites in RNA (Angew. Chem. Int. Ed. 21/2018)

scholarly article by Katja Hartstock et al published 14 April 2018 in Angewandte Chemie International Edition

Interaction between the C. elegans centriolar protein SAS-5 and microtubules facilitates organelle assembly

scientific article published on 24 January 2018

Matching tRNA modifications in humans to their known and predicted enzymes

scientific article published on 18 March 2019

Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation

scientific article

Modification of tRNA(Lys) UUU by elongator is essential for efficient translation of stress mRNAs.

scientific article

Modify or die?--RNA modification defects in metazoans

scientific article

Molecular basis for the bifunctional Uba4-Urm1 sulfur-relay system in tRNA thiolation and ubiquitin-like conjugation

scientific article published on 09 September 2020

Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly.

scientific article published on 14 August 2017

Nano LC-MS using capillary columns enables accurate quantification of modified ribonucleosides at low femtomol levels

scientific article published on 16 July 2018

Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity

scientific article published on 4 June 2015

PDCD4 controls the G1/S-phase transition in a telomerase-immortalized epithelial cell line and affects the expression level and translation of multiple mRNAs

scientific article published on 17 February 2020

Regulated HsSAS-6 levels ensure formation of a single procentriole per centriole during the centrosome duplication cycle

scientific article

Repulsive cues combined with physical barriers and cell-cell adhesion determine progenitor cell positioning during organogenesis

scientific article

SAS-4 is essential for centrosome duplication in C elegans and is recruited to daughter centrioles once per cell cycle

scientific article

SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells

scientific article

SMITER—A Python Library for the Simulation of LC-MS/MS Experiments

scientific article published on 11 March 2021

Stepwise Clearance of Repressive Roadblocks Drives Cardiac Induction in Human ESCs

scientific article published on 01 April 2016

Stepwise Clearance of Repressive Roadblocks Drives Cardiac Induction in Human ESCs.

scientific article published on 29 December 2015

Structures to the people!

scientific article published on 8 July 2015

The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan

scientific article published on 6 September 2017

The Uba4 domain interplay is mediated via a thioester that is critical for tRNA thiolation through Urm1 thiocarboxylation.

scientific article

The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates

scientific article published in Nature Communications

The epitranscriptome in translation regulation: mRNA and tRNA modifications as the two sides of the same coin?

scientific article published on 27 June 2019

The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins

scientific article published on 21 March 2019

The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA

scientific article published on 01 January 2020

The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A)

scientific journal article

Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression

scientific article published on 26 September 2019

Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA.

scientific article

Urm1 at the crossroad of modifications. 'Protein Modifications: Beyond the Usual Suspects' Review Series

scientific article (publication date: December 2008)

Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause

scientific article published on 30 October 2020

Wobble uridine modifications-a reason to live, a reason to die?!

scientific article published on 23 February 2017

miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo

scientific article

pyQms enables universal and accurate quantification of mass spectrometry data.

scientific article published on 20 July 2017

pymzML v2.0: introducing a highly compressed and seekable gzip format.

scientific article published on 31 January 2018

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